TY  - JOUR
TI  - DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS
AB  - Objective: The aim of this study was to determinate of the effective time ofdifferent denture cleanser tablets on the removal of Candida albicans on variousbase resins.Materials and Methods: Conventional heat cured resin, high impact resin,autopolymerized resin, and polyamide resin were used. 160 samples were preparedfor each resin type. The biofilm of C. albicans was formed on the resins and thenexposed to alkaline peroxide tablet and enzymatic tablets for 3, 5, 10, 20, 40, 80,160 and 200 minutes. Cell viability was assessed by MTT test. 3-way ANOVAwas used for statistical analysis.Results: The effect of resin type, tablet type and application time on cell viabilityof C. albicans were found to be significant (p<0.05). Cell death was at least 65%on the resins even at the minimum time. Furthermore, as the duration ofadministration of both tablets increased, cell viability in all resins tended todecrease. The administration of both tablets on all resins for 10 min resulted inapproximately 80% cell death. Additionally, the most significant antimicrobialactivities of the tablets were determined at 20th minutes. The alkaline peroxidetablet on all base resins for application periods of 3 to 200 minutes was generallymore effective than the enzymatic tablet.Conclusions: Alkaline peroxide and enzymatic cleanser tablets showedremarkable anticandidal activity for all resins. The patients with risk of C. albicansinfection should keep their prostheses in cleanser tablets for at least 20 minutes.Furthermore, the anticandidal effect tended to increase with prolonged exposuretime.
AU  - hayran, yeliz
DO  - 10.7126/cumudj.566223
PY  - 2019
JO  - Cumhuriyet Dental Journal 
VL  - 22
IS  - 3
SN  - 1302-5805
SP  - 325
EP  - 335
DB  - TRDizin
UR  - http://search/yayin/detay/386156
ER  -