TY  - JOUR
TI  - Fatal DRESS Syndrome Without Eosinophilia After Coronary Artery Bypass Grafting
AB  - Drug reaction with eosinophilia and systemic symptom(DRESS) is a life threatening adverse drug reaction. A 58-year-oldfemale patient presented to our hospital with nausea and vomiting 2weeks after elective coronary artery bypass grafting (CABG). She hadused metoprololol, asetilsalycilic asit and furosemide after the operation. Blood tests showed neutropenia, low eosinophil levels, elevatedliver biomarkers. Our case had fever, a morbilliform rash, bone marrow failure and hepatitis. Clinical (fever, exanthema, facial oedema)and laboratory (pansitopenia with liver and pulmonary involvement)findings raised the suspicion of DRESS and the patient was started on1 mg/kg intravenous (IV) prednisone daily and IV immunoglobulin(IVIG) at 2 g/kg. She died on the the seventh ICU day. DRESS syndrome is a fatal drug hypersensitivity reaction with cutaneous andsystemic involvements. Multidisciplinary care is important for a successful treatment.
AU  - yalcin, mihriban
AU  - Karakök, Hilayda
AU  - Kurt, Celali
DO  - 10.5336/dermato.2019-65810
PY  - 2020
JO  - Türkiye Klinikleri Dermatoloji Dergisi
VL  - 30
IS  - 2
SN  - 2146-9016
SP  - 66
EP  - 68
DB  - TRDizin
UR  - http://search/yayin/detay/386348
ER  -