Earthquake has been on the agenda of humanity throughout history. The characteristic of this disaster, the time, location, and magnitude of which is unknown, is that it causes loss of life and property. Therefore, societies with weak economic power and insufficient precaution are more affected. It is not correct to interpret earthquakes and accidents with an understanding of inevitable fate or to perceive them as divine punishment without taking precautions. On the contrary, everything that exists in the universe has been created in a certain measure and order. Earthquakes occur within the scope of these measures and laws by the discharge of energy accumulated on the fault fractures in the ground. Islam holds human responsible for all natural disasters and accidents in a comprehensive manner, as foreseen by tawakkul, will, destiny, reason and science. According to this, it is a religious and humanitarian duty to take precautions for possible natural disasters, traffic and work accidents by considering the developing technical tools and equipment of the age. As a matter of fact, the measures taken by Japan and developed countries regarding these events are successful. In order to contribute to this field, it has been deemed appropriate to conduct this study under the title “Earthquake and Responsibility Awareness in the Context of Tawakkul and Destiny”.