Yıl: 2003 Cilt: 66 Sayı: 1 Sayfa Aralığı: 28 - 33 Metin Dili: Türkçe

Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi

Öz:
Geçen 30 yıl içinde, gelişmiş ülkelerde midenin distal yerleşimli adenokanserlerinin azaldığı, proksimal adenokanserlerinin arttığı bildirilmektedir. Distal adenokanserlerin sıklığındaki azalmanın, Helicobacter pylori eradikasyonu ile paralellik gösterdiği iddia edilmektedir. Bu çalışmada 1995-2001 yılları arasında Yüzüncü Yıl Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim Dalı'nda endoskopik ve histolojik olarak mide kanseri tanısı almış 459 olgu retrospektif olarak değerlendirildi. Olguların 304'ü (%66) erkek, 155'i (%34) kadın idi. Yaş ortalaması 56.7±12.4 (17-91 yaş arası) olup, erkek/ kadın oranı 1.9 olarak tespit edildi. Olguların %74'ü 40-70 yaş arasında olup, en küçük görülme yaşı erkeklerde 25, kadınlarda 17 olarak bulundu. Lokalizasyon olarak; olguların 163'ü (%35.5) mide orta kısım, 159'ü (%34.6) 1/3 mide distal, 132'si (%28.7) 1/3 mide proksimal, 5'i (%1) diffüz tutulum gösteriyordu. Histopatolojik özellikleri; 451'i (%98) adenokanser, 7'si (%1.5) epidermoid, biri küçük hücreli kanser idi. Sonuç olarak; son yıllarda proksimal gastrik kanserlerin sıklığında belirgin artış gözlenmesine rağ-men, serimizde korpus lokalizasyonu en yaygın tutulum yeri olarak belirlendi. Olguların ortalama %43'ünde doku düzeyinde (antrum %53, korpus %45, kardia %28) Helicobacter pylori pozitif bulundu.
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The histopathological characteristics and localization of gastric cancer in Van and its around

Öz:
The past thirty years it is known that the distal localization of adenocarcinomas was in a trend of decrease and proximal adenocarcinomas increased. It has been claimed that the decrease in the incidence of distal adenocarcinomas was associated with the decrease in the incidence of Helicobacter pylori. In this study 459 cases who were diagnosed to have gastric cancer within the years of 1995-2001 in the gastroenterology department of the Research Hospital of Yüzüncü Yil University were retrospectively evaluated. As for the localizations, our cases revealed the following manifestations: 163 cases middle stomach; 159 distal stomach; and 132 proximal stomach; 5 cases were detected to have diffused involvement. Mean age of all cases was found to be 56.7 (aged between 17-91). Male/female range was found as 1.9 and seventy-four percent of our cases were aged between 40-70. The youngest age for the condition to be prevailed was 25 in the males and 17 in females. The histopathological characteristics of our cases were conceived as thus: 451 cases adenocarcinoma; 7 cases squamous cell carcinoma and a single one was detected to have small cell carcinoma. In conclusion: in spite of the fact that in the recent years there is a remarkable increase in the prevalence of proximal gastric cancers, the middle localizations of the stomach were found to be the most commonly-observed involvement in our series. Forty-three percent of them were found Helicobacter pylori positive in tissue (53% antrum, 45% corpus and 28% cardia).
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Fen > Tıp > Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA TUNCER İ, TOPÇU N, UĞRAŞ S, TÜRKDOĞAN M, KOTAN Ç, UYGAN İ (2003). Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, 66(1), 28 - 33.
Chicago TUNCER İLYAS,TOPÇU Nazan,UĞRAŞ Serdar,TÜRKDOĞAN M. Kürşad,KOTAN Çetin,UYGAN İsmail Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası 66, no.1 (2003): 28 - 33.
MLA TUNCER İLYAS,TOPÇU Nazan,UĞRAŞ Serdar,TÜRKDOĞAN M. Kürşad,KOTAN Çetin,UYGAN İsmail Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, vol.66, no.1, 2003, ss.28 - 33.
AMA TUNCER İ,TOPÇU N,UĞRAŞ S,TÜRKDOĞAN M,KOTAN Ç,UYGAN İ Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası. 2003; 66(1): 28 - 33.
Vancouver TUNCER İ,TOPÇU N,UĞRAŞ S,TÜRKDOĞAN M,KOTAN Ç,UYGAN İ Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi. İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası. 2003; 66(1): 28 - 33.
IEEE TUNCER İ,TOPÇU N,UĞRAŞ S,TÜRKDOĞAN M,KOTAN Ç,UYGAN İ "Van ve çevresinde saptanan mide kanserlerinin lokalizasyonu ve histopatolojik özellikleri: 466 olgunun analizi." İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, 66, ss.28 - 33, 2003.