TY  - JOUR
TI  - Evaluation of Risk Factors for Carbapenem-Resistant Klebsiella Pneumoniae Bacteremia
AB  - Objective: In recent years, carbapenem-resistant Klebsiella pneumoniae infections havebecome an important health problem in our country and all over the world. In this study,we aimed to identify the risk factors of carbapenem-resistant K. pneumoniae bacteremia.Methods: Patients who suffered from Klebsiella pneumoniae bacteremia between December2016 and May 2018 were included prospectively in this study. Patients were divided intogroups according to carbapenem resistance and risk factors were analyzed under variableand multivariable logistic regression model.Results: Of the fifty-three patients were included in this study, 27 patients infected withcarbapenem-resistant K. pneumoniae and 26 patients infected with carbapenem-suspectibleK. pneumoniae. Risk factors for carbapenem-resistant K. pneumoniae bacteremia accordingto univariate analysis were listed prior hospitalization (p=0.043; OR=3.20; 95% CI: 1.04–9.85), admission to intensive care unit (p=0.001; OR=10.91; 955 CI: 2.61–45.6), use of beta-lactams/beta-lactamase inhibitor combination (p<0.001; OR=41.67; 95% CI: 7.57–229.2)and use of glycopeptides (p=0.001; OR=7.92; 95% CI: 2.31–27.1). Before hospitalization(p=0.016; OR=9.64; 95% CI: 1.54–60.46) and use of beta-lactams/beta-lactamase, inhibitorcombination (p<0.001; OR=38.45; 95% CI: 6.04–244.85) were identified as independent riskfactors for carbapenem resistance in multivariate analysis.Conclusion: According to our study, before hospitalization, the use of beta-lactams/betalactamaseinhibitor combination was the major risk factor for carbapenem-resistant Klebsiellapneumoniae bacteremia.
AU  - Gencer, Serap
AU  - KIRAN, Pınar
AU  - Batirel, Ayse
DO  - 10.14744/scie.2019.48569
PY  - 2020
JO  - Southern Clinics of Istanbul Eurasia
VL  - 31
IS  - 1
SN  - 2587-0998
SP  - 54
EP  - 58
DB  - TRDizin
UR  - http://search/yayin/detay/388620
ER  -