Evaluation of the Wound Healing Potential of Teucrioside
Yıl: 2018 Cilt: 2 Sayı: 1 Sayfa Aralığı: 16 - 19 Metin Dili: İngilizce DOI: 10.32571/ijct.345050 İndeks Tarihi: 08-01-2021
Evaluation of the Wound Healing Potential of Teucrioside
Öz: Herbal medicines are being used for primary health care due to their efficacy, safety and less side effects. Teucrium genus is a member of the Lamiaceae family, which is a medicinal plant have been used in traditional medicine, especially for wound healing and inflammatory conditions. Teucroside, 9′-decarboxyrosmarinic acid-4′-O-α-rhamnosyl-(1‴→6‴)-O-β-galactosyl-(1‴→4″)-O-α-rhamnoside is a natural phenolic compund which is isolated and identified from of Teucrium genus. In this study, because of bioactive properties of Teucrioside, it was decided to examine its potential wound healing effect. Wound healing process was investigated by in vitro scratch assay which was an easy, inexpensive and well developed method to measure cell migration. In this context, firstly, cell viability was determined by MTT assay and the results were evaluated to find effective concentration for wound healing. Then the cells were incubated for 48 h with extract with defined concentration. Finally, after 48 hours of incubation with teucroside, the wound healing was calculated as 47%. When the data were compared with untreated control (49%), it was concluded that teucroside had not wound healing potential.
Anahtar Kelime: Teukrosit’in yara iyileştirme potansiyelinin değerlendirilmesi
Öz: Bitkisel ilaçlar, etkinliği, güvenliği ve daha az yan etkileri nedeniyle primer sağlık hizmetindekullanılmaktadır. Teucrium cinsi, özellikle yara iyileşmesi ve enflamatuardurumlar için geleneksel tıpta kullanılan bir tıbbi bitki olan Lamiaceae familyasının bir üyesidir.Teukrosit,9′-dekarboksirosmarinik asit-4′-O-α-ramnozil-(1′′′→6′′′)-O-β-galaktozil-(1′′′→4′′)-O-α-ramnozid,Teucrium cinsindenizole edilen ve karakterize edilen doğal fenolik bir bileşiktir. Bu çalışmada,Teukrosit’inbiyoaktif özelliklerden dolayı onun potansiyel yara iyileştirme etkileriniincelemeyekarar verilmiştir.Yara iyileşme süreci; kolay, ucuz ve hücre migrasyonunu ölçmek için iyi geliştirilmişbir metot olanin vitro çizik testi ile araştırılmıştır.Bu bağlamdailk olarak, hücre canlılığı MTT analizi ile gerçekleştirildive sonuçlar,yara iyileşmesinde etkin dozu bulmak için değerlendirildi.Ardından, hücreler, belli konsantrasyonasahip özütleme ile 48 saatliğine inkübe edildi.Sonolarak, Teukrositile 48 saatlik inkübasyon sonunda, yara iyileşmesi %47 olarak hesaplanmıştır.Bu veriler, negatif kontrolle (%49) karşılaştırıldığındateukrosit’in, yara iyileşme potansiyelinesahip olmadığı sonucuna varıldı.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Erden Tayhan S, Bilgin S, ELMASTAŞ M (2018). Evaluation of the Wound Healing Potential of Teucrioside. , 16 - 19. 10.32571/ijct.345050 |
| Chicago | Erden Tayhan Secil,Bilgin Sema,ELMASTAŞ MAHFUZ Evaluation of the Wound Healing Potential of Teucrioside. (2018): 16 - 19. 10.32571/ijct.345050 |
| MLA | Erden Tayhan Secil,Bilgin Sema,ELMASTAŞ MAHFUZ Evaluation of the Wound Healing Potential of Teucrioside. , 2018, ss.16 - 19. 10.32571/ijct.345050 |
| AMA | Erden Tayhan S,Bilgin S,ELMASTAŞ M Evaluation of the Wound Healing Potential of Teucrioside. . 2018; 16 - 19. 10.32571/ijct.345050 |
| Vancouver | Erden Tayhan S,Bilgin S,ELMASTAŞ M Evaluation of the Wound Healing Potential of Teucrioside. . 2018; 16 - 19. 10.32571/ijct.345050 |
| IEEE | Erden Tayhan S,Bilgin S,ELMASTAŞ M "Evaluation of the Wound Healing Potential of Teucrioside." , ss.16 - 19, 2018. 10.32571/ijct.345050 |
| ISNAD | Erden Tayhan, Secil vd. "Evaluation of the Wound Healing Potential of Teucrioside". (2018), 16-19. https://doi.org/10.32571/ijct.345050 |
| APA | Erden Tayhan S, Bilgin S, ELMASTAŞ M (2018). Evaluation of the Wound Healing Potential of Teucrioside. International Journal of Chemistry and Technology (IJCT), 2(1), 16 - 19. 10.32571/ijct.345050 |
| Chicago | Erden Tayhan Secil,Bilgin Sema,ELMASTAŞ MAHFUZ Evaluation of the Wound Healing Potential of Teucrioside. International Journal of Chemistry and Technology (IJCT) 2, no.1 (2018): 16 - 19. 10.32571/ijct.345050 |
| MLA | Erden Tayhan Secil,Bilgin Sema,ELMASTAŞ MAHFUZ Evaluation of the Wound Healing Potential of Teucrioside. International Journal of Chemistry and Technology (IJCT), vol.2, no.1, 2018, ss.16 - 19. 10.32571/ijct.345050 |
| AMA | Erden Tayhan S,Bilgin S,ELMASTAŞ M Evaluation of the Wound Healing Potential of Teucrioside. International Journal of Chemistry and Technology (IJCT). 2018; 2(1): 16 - 19. 10.32571/ijct.345050 |
| Vancouver | Erden Tayhan S,Bilgin S,ELMASTAŞ M Evaluation of the Wound Healing Potential of Teucrioside. International Journal of Chemistry and Technology (IJCT). 2018; 2(1): 16 - 19. 10.32571/ijct.345050 |
| IEEE | Erden Tayhan S,Bilgin S,ELMASTAŞ M "Evaluation of the Wound Healing Potential of Teucrioside." International Journal of Chemistry and Technology (IJCT), 2, ss.16 - 19, 2018. 10.32571/ijct.345050 |
| ISNAD | Erden Tayhan, Secil vd. "Evaluation of the Wound Healing Potential of Teucrioside". International Journal of Chemistry and Technology (IJCT) 2/1 (2018), 16-19. https://doi.org/10.32571/ijct.345050 |
