A Simple Approach for Controlling an Open-Source Syringe Pump

AKKOYUN, FATIH; Ozcelik, Adem

doi:10.26701/ems.769837

A Simple Approach for Controlling an Open-Source Syringe Pump

Fatih Akkoyun, (Aydın Adnan Menderes Üniversitesi, Mühendislik Fakültesi, Makine Mühendisliği Bölümü, Türkiye)

Adem Ozcelik (Aydın Adnan Menderes Üniversitesi, Mühendislik Fakültesi, Makine Mühendisliği Bölümü, Türkiye)

European Mechanical Science

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Yıl: 2020 Cilt: 4 Sayı: 4 Sayfa Aralığı: 166 - 170 Metin Dili: İngilizce DOI: 10.26701/ems.769837 İndeks Tarihi: 22-01-2021

A Simple Approach for Controlling an Open-Source Syringe Pump

Öz:

Precise control of fluid flows in microfluidics is crucial for various applications in lab-on-a-chip and pointof-care diagnostics. Standard bench-top equipment for providing this capability are syringe pumps. However,high cost of these systems limit their availability in low resourced laboratories. There are various open-sourcedalternative syringe pump systems that can be fabricated and assembled using 3D printing, but they lack versatilecontrol and flow rate characterization that are required for microfluidic applications. We report a simple andcost-effective approach to control an open-source multi-channel syringe pump. Simultaneous and adjustableflow control, and detailed characterization of the volume flow rates for different syringe volumes are alsodemonstrated.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

[1] Weibel, D., Whitesides, G. (2006). Applications of microfluidics in chemical biology. Current Opinion in Chemical Biology, 10(6): 584–91. doi: 10.1016/j.cbpa.2006.10.016.
[2] Whitesides, G.M. (2006). The origins and the future of microfluidics. Nature, 442(7101): 368–73. doi: 10.1038/nature05058.
[3] Rivet, C., Lee, H., Hirsch, A., Hamilton, S., Lu, H. (2011). Microfluidics for medical diagnostics and biosensors. Chemical Engineering Science, 66(7): 1490–507. doi: 10.1016/j.ces.2010.08.015.
[4] Tosun, E., Ozgur, T., Ozgur, C., Ozcanli, M., Serin, H., Aydin, K. (2017). Comparative analysis of various modelling techniques for emission prediction of diesel engine fueled by diesel fuel with nanoparticle additives. European Mechanical Science, 1(1): 15–23. doi: 10.26701/ ems.320490.
[5] Kaleli, A.R. (2019). Gray based Fuzzy Gain-Scheduling PID Controller Design for Air-Fuel System Under Variable Engine Operating Conditions. European Mechanical Science, 3(4): 125–32. doi: 10.26701/ems.599452.
[6] Lu, M., Ozcelik, A., Grigsby, C.L.C.L. Zhao, Y., Guo, F., Leong, K.W.K.W., et al., (2016). Microfluidic hydrodynamic focusing for synthesis of nanomaterials. Nano Today, 11(6): 778–92. doi: 10.1016/j.nantod.2016.10.006.
[7] Li, Z., Mak, S.Y., Sauret, A., Shum, H.C. (2014). Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy. Lab on a Chip, 14(4): 744. doi: 10.1039/c3lc51176f.
[8] Wijnen, B., Hunt, E.J., Anzalone, G.C., Pearce, J.M. (2014). Open-Source Syringe Pump Library. PLoS ONE, 9(9): e107216. doi: 10.1371/ journal.pone.0107216.
[9] Pearce, J.M. (2014). Cut costs with open-source hardware. Nature, 505(7485): 618–618. doi: 10.1038/505618d.
[10] Pearce, J.M. (2012). Building Research Equipment with Free, Open-Source Hardware. Science, 337(6100): 1303–4. doi: 10.1126/ science.1228183.
[11] Juarez, A., Maynard, K., Skerrett, E., Molyneux, E., Richards-Kortum, R., Dube, Q., et al. (2016). AutoSyP: A Low-Cost, Low-Power Syringe Pump for Use in Low-Resource Settings. The American Journal of Tropical Medicine and Hygiene, 95(4): 964–9. doi: 10.4269/ajtmh.16-0285.
[12] Skerrett, E., Kommwa, E., Maynard, K., Juarez, A., Mataya, R., Richards-Kortum, R., et al. (2017). Evaluation of a low-cost, low-power syringe pump to deliver magnesium sulfate intravenously to pre-eclamptic women in a Malawian referral hospital. BMC Pregnancy and Childbirth, 17(1): 191. doi: 10.1186/s12884-017-1382-9.
[13] Zhang, P., Bachman, H., Ozcelik, A., Huang, T.J. (2020). Acoustic Microfluidics. Annual Review of Analytical Chemistry, 13(1): 17–43. doi: 10.1146/annurev-anchem-090919-102205.
[14] Wu, M., Ozcelik, A., Rufo, J., Wang, Z., Fang, R., Jun Huang, T. (2019). Acoustofluidic separation of cells and particles. Microsystems & Nanoengineering, 5(1): 32. doi: 10.1038/s41378-019-0064-3.
[15] Lake, J.R., Heyde, K.C., Ruder, W.C. (2017). Low-cost feedback-controlled syringe pressure pumps for microfluidics applications. PLOS ONE, 12(4): e0175089. doi: 10.1371/journal.pone.0175089.
[16] Guelig, D., Bauer, J., Wollen, A., Schiller, C., Sherman-Konkle, J., Roche, A., et al. (2017). Design of a Novel, Adjustable Flow Rate, Reusable, Electricity-Free, Low-Cost Syringe Infusion Pump. Journal of Medical Devices, 11(4): 1–6. doi: 10.1115/1.4037935.
[17] Amarante, L.M., Newport, J., Mitchell, M., Wilson, J., Laubach, M. (2019). An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes. Eneuro, 6(5): ENEURO.0240-19.2019. doi: 10.1523/ENEURO.0240-19.2019.
[18] Booeshaghi, A.S., Beltrame, E. da V., Bannon, D., Gehring, J., Pachter, L. (2019). Principles of open source bioinstrumentation applied to the poseidon syringe pump system. Scientific Reports, 9(1): 12385. doi: 10.1038/s41598-019-48815-9.
[19] Pusch, K., Hinton, T.J., Feinberg, A.W. (2018). Large volume syringe pump extruder for desktop 3D printers. HardwareX, 3(November 2017): 49–61. doi: 10.1016/j.ohx.2018.02.001.
[20] Cubberley, M.S., Hess, W.A. (2017). An Inexpensive Programmable Dual-Syringe Pump for the Chemistry Laboratory. Journal of Chemical Education, 94(1): 72–4. doi: 10.1021/acs.jchemed.6b00598.
[21] Garcia, V.E., Liu, J., DeRisi, J.L. (2018). Low-cost touchscreen driven programmable dual syringe pump for life science applications. HardwareX, 4: e00027. doi: 10.1016/j.ohx.2018.e00027.

APA	AKKOYUN F, Ozcelik A (2020). A Simple Approach for Controlling an Open-Source Syringe Pump. , 166 - 170. 10.26701/ems.769837
Chicago	AKKOYUN FATIH,Ozcelik Adem A Simple Approach for Controlling an Open-Source Syringe Pump. (2020): 166 - 170. 10.26701/ems.769837
MLA	AKKOYUN FATIH,Ozcelik Adem A Simple Approach for Controlling an Open-Source Syringe Pump. , 2020, ss.166 - 170. 10.26701/ems.769837
AMA	AKKOYUN F,Ozcelik A A Simple Approach for Controlling an Open-Source Syringe Pump. . 2020; 166 - 170. 10.26701/ems.769837
Vancouver	AKKOYUN F,Ozcelik A A Simple Approach for Controlling an Open-Source Syringe Pump. . 2020; 166 - 170. 10.26701/ems.769837
IEEE	AKKOYUN F,Ozcelik A "A Simple Approach for Controlling an Open-Source Syringe Pump." , ss.166 - 170, 2020. 10.26701/ems.769837
ISNAD	AKKOYUN, FATIH - Ozcelik, Adem. "A Simple Approach for Controlling an Open-Source Syringe Pump". (2020), 166-170. https://doi.org/10.26701/ems.769837

APA	AKKOYUN F, Ozcelik A (2020). A Simple Approach for Controlling an Open-Source Syringe Pump. European Mechanical Science, 4(4), 166 - 170. 10.26701/ems.769837
Chicago	AKKOYUN FATIH,Ozcelik Adem A Simple Approach for Controlling an Open-Source Syringe Pump. European Mechanical Science 4, no.4 (2020): 166 - 170. 10.26701/ems.769837
MLA	AKKOYUN FATIH,Ozcelik Adem A Simple Approach for Controlling an Open-Source Syringe Pump. European Mechanical Science, vol.4, no.4, 2020, ss.166 - 170. 10.26701/ems.769837
AMA	AKKOYUN F,Ozcelik A A Simple Approach for Controlling an Open-Source Syringe Pump. European Mechanical Science. 2020; 4(4): 166 - 170. 10.26701/ems.769837
Vancouver	AKKOYUN F,Ozcelik A A Simple Approach for Controlling an Open-Source Syringe Pump. European Mechanical Science. 2020; 4(4): 166 - 170. 10.26701/ems.769837
IEEE	AKKOYUN F,Ozcelik A "A Simple Approach for Controlling an Open-Source Syringe Pump." European Mechanical Science, 4, ss.166 - 170, 2020. 10.26701/ems.769837
ISNAD	AKKOYUN, FATIH - Ozcelik, Adem. "A Simple Approach for Controlling an Open-Source Syringe Pump". European Mechanical Science 4/4 (2020), 166-170. https://doi.org/10.26701/ems.769837