Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri

Özge TEMİZ (Çukurova Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Adana, Türkiye)
JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES
2 0
Yıl: 2019 Cilt: 4 Sayı: 1 Sayfa Aralığı: 43 - 47 Metin Dili: Türkçe İndeks Tarihi: 26-01-2021

Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri

Öz:
Bu Araştırmada, fungisit propiconazole’un 0.5 ppb ve 2.5 ppb derişim etkilerinde 7 gün ve 28 gün sürelerde Oreochromisniloticus’un karaciğer dokusunda, süperoksit dismutaz (SOD), katalaz (CAT), glutatyon peroksidaz (GPx) ve glutatyon S transferaz (GST)antioksidan sistem enzim aktiviteleri ve oksidatif stres parametreleri glutatyon (GSH) ve tiyobarbitürik asit reaktif maddeleri (TBARS)miktarlarındaki değişimler spektrofotometrik yöntemlerle belirlenmiştir.Çalışmamızda karaciğer dokusunda GSH miktarı ve GSH-bağımlı GPx ve GST aktivitesi 7. günde artarken; 28. günde GSHmiktarında azalma ve GST aktivitelerinde artış belirlenmiştir. SOD ve CAT aktiviteleri 7. günde artarken 28. günde azalmıştır. TBARSdüzeylerinde propiconazole etkisinde süreye ve derişime bağlı olarak artış göstermektedir.Çalışma sonuçlarına göre propiconazole etkisinde O. niloticus’da antioksidan sistem enzim aktivitelerinde ve oksidatif stresparametrelerindeki değişimler propiconazole’un hepatotoksik etkiye neden olduğu belirlenmiştir.
Anahtar Kelime:

Effects of Fungicide Propiconazole on Oxidative Stress Parameters and Antioxidant System Enzymes in Liver of Oreochromis niloticus

Öz:
In this research, 0.5 ppb and 2.5 ppb effect of fungicide propiconazole in 7 days and 28 days periods in liver tissue of Oreochromis niloticus, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione S transferase (GST) antioxidant system enzyme activities and oxidative stress parameters glutathione (GSH) and thiobarbituric acid reagents (TBARS) were determined by spectrophotometric methods. In our study, GSH levels and GSH-dependent GPx and GST activity increased in 7 days. In 28 days, decrease in GSH and increase in GST activities were determined. SOD and CAT activities increased in 7 days and decreased in 28 days. In TBARS levels, the time and concentrations -related increase in the effect of propiconazole According to the results of the study; The effect of propiconazole on antioxidant enzyme activity and oxidative stress parameters in O. niloticus was determined to cause hepatotoxic effect.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA TEMİZ Ö (2019). Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. , 43 - 47.
Chicago TEMİZ Özge Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. (2019): 43 - 47.
MLA TEMİZ Özge Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. , 2019, ss.43 - 47.
AMA TEMİZ Ö Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. . 2019; 43 - 47.
Vancouver TEMİZ Ö Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. . 2019; 43 - 47.
IEEE TEMİZ Ö "Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri." , ss.43 - 47, 2019.
ISNAD TEMİZ, Özge. "Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri". (2019), 43-47.
APA TEMİZ Ö (2019). Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, 4(1), 43 - 47.
Chicago TEMİZ Özge Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES 4, no.1 (2019): 43 - 47.
MLA TEMİZ Özge Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, vol.4, no.1, 2019, ss.43 - 47.
AMA TEMİZ Ö Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES. 2019; 4(1): 43 - 47.
Vancouver TEMİZ Ö Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES. 2019; 4(1): 43 - 47.
IEEE TEMİZ Ö "Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri." JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, 4, ss.43 - 47, 2019.
ISNAD TEMİZ, Özge. "Oreochromis niloticus'un Karaciğerinde Fungisit Propiconazole'un Oksidatif Stres Parametreleri ve Antioksidan Sistem Enzimleri Üzerine Etkileri". JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES 4/1 (2019), 43-47.
Sayfa Oluşturulma Tarihi
23-04-2024 16:33

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