Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30
Yıl: 2019 Cilt: 41 Sayı: 4 Sayfa Aralığı: 344 - 352 Metin Dili: İngilizce DOI: 10.20515/otd.427647 İndeks Tarihi: 31-03-2021
Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30
Öz: Our aim is to compare neostigmin versus sugammadex in reversal of neuromuscular blockade of vecu-ronium after abdominal surgery of obese patients whose BMI ≥30. This study is performed on 70 patients whose BMI ≥30 and ASA I-II-III. They are 18-65 years old and scheduled for any abdominal surgery under general anesthesia. They are monitorized with TOF-watch for neuromuscular blockade and standard non-invasive monitorization. Vecuronium 0,1 mg/kg is given during anesthesia induction. According to type of surgery, extra doses of vecuronium 0.01-0.02 mg/kg is added to keep TOF between 0-2. During recovery period, when TOF number exceeds 2 and diaphragmatic movements begin, group sug received sugammadex 2 mg/kg and group neo received neostigmin 0,05 mg/kg with atropine 0,02 mg/kg. When TOF ratio becomes 0,9 and clinical evaluation is completed, patient is extubed. Group sug and neo recovery durations from TOF2 to TOF 0.9 are respectively 3,7 minutes and 14 minutes. (p<0,001) Demographic data revealed no significant difference between Group sug and group neo except BMI and surgery type (p=0,017 , p=0,008 ). PORC(Postoperative residual curarization) is a predicted complication in obesity. Sugammadex is superior than neostigmine especially in obese critical patients in terms of effective faster and safer airway management.
Anahtar Kelime: Batın Cerrahisi Uygulanan BMI≥30 Üzerinde olan Obez Hastalarda Nöromuskuler Bloğun Geri Döndürülmesinde Neostigmin ve Sugammadeksin Karşılaştırılması
Öz: Bu çalışmadaki amacımız BMI≥30 üzerindeki obez hastalarda , batın cerrahisi operasyonlarında, vekuronyum ile sağlanan nöromüsküler bloğun geri döndürülmesinde neostigmin ve sugammadeksin etkinliğinin karşılaştırılmasıdır. Bu çalışma genel anestezi altında, batın cerrahisi planlanan, ASA I-II-III olan, 18-65 yaş arası, BMI≥30 üzerindeki 70 hastada yapıldı. Noninvaziv monitorizasyonla birlikte nöromuskuler monitorizasyon için TOF - Watch uygulandı. Anestezi indüksiyonunda kas gevşetici olarak vekuronyum 0.1 mg/kg uygulandı, cerrahinin türüne göre TOF 0-2 arasında olacak şekilde 0.01 -0.02 (mg/kg) vekuronyum ile ek doz uygulandı. Derlenme döneminde TOF sayısının 2 nin üzerinde ve klinik olarak diyafram haraketlerinin başladıktan sonra nöromuskuler bloğun geri döndürülmesinde sugammadeks (grup sug) 2mg/kg ve neostigmin (grup neo) 0.05mg/kg ile birlikte atropin 0.02mg/kg uygulandı . TOF oranı 0.9 olduğunda ve hastanın klinik değerlendirilmesi sonucu extübe edildi. Grup sug ve neo hastalarda T2’den TOF oranı 0.9’a ulaşma süresi sırasıyla 3,7 dk ve 14 dk idi (p<0,001). Demografik verilerde Grup sug ve grup neo arasında BMI ve ameliyat türü dışında anlamlı fark bulunmadı (p=0,017 , p=0,008 ). PORC obezitede öngörülebilir bir komplikasyondur. Sugammadeks, neostigmine göre obezite gibi kritik hastalarda daha hızlı ve güvenli hava yolu sağlamada etkin bir ajan olduğunu düşünmekteyiz.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Onay M, ŞENTÜRK YILMAZ E (2019). Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. , 344 - 352. 10.20515/otd.427647 |
| Chicago | Onay Meryem,ŞENTÜRK YILMAZ Elif Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. (2019): 344 - 352. 10.20515/otd.427647 |
| MLA | Onay Meryem,ŞENTÜRK YILMAZ Elif Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. , 2019, ss.344 - 352. 10.20515/otd.427647 |
| AMA | Onay M,ŞENTÜRK YILMAZ E Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. . 2019; 344 - 352. 10.20515/otd.427647 |
| Vancouver | Onay M,ŞENTÜRK YILMAZ E Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. . 2019; 344 - 352. 10.20515/otd.427647 |
| IEEE | Onay M,ŞENTÜRK YILMAZ E "Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30." , ss.344 - 352, 2019. 10.20515/otd.427647 |
| ISNAD | Onay, Meryem - ŞENTÜRK YILMAZ, Elif. "Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30". (2019), 344-352. https://doi.org/10.20515/otd.427647 |
| APA | Onay M, ŞENTÜRK YILMAZ E (2019). Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. Osmangazi Tıp Dergisi, 41(4), 344 - 352. 10.20515/otd.427647 |
| Chicago | Onay Meryem,ŞENTÜRK YILMAZ Elif Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. Osmangazi Tıp Dergisi 41, no.4 (2019): 344 - 352. 10.20515/otd.427647 |
| MLA | Onay Meryem,ŞENTÜRK YILMAZ Elif Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. Osmangazi Tıp Dergisi, vol.41, no.4, 2019, ss.344 - 352. 10.20515/otd.427647 |
| AMA | Onay M,ŞENTÜRK YILMAZ E Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. Osmangazi Tıp Dergisi. 2019; 41(4): 344 - 352. 10.20515/otd.427647 |
| Vancouver | Onay M,ŞENTÜRK YILMAZ E Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30. Osmangazi Tıp Dergisi. 2019; 41(4): 344 - 352. 10.20515/otd.427647 |
| IEEE | Onay M,ŞENTÜRK YILMAZ E "Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30." Osmangazi Tıp Dergisi, 41, ss.344 - 352, 2019. 10.20515/otd.427647 |
| ISNAD | Onay, Meryem - ŞENTÜRK YILMAZ, Elif. "Comparison of Neostigmin Versus Sugammadex in Reversal of Neuromuscular Blockade after Abdominal Surgery of Obese Patients Whose Bmi ≥30". Osmangazi Tıp Dergisi 41/4 (2019), 344-352. https://doi.org/10.20515/otd.427647 |
