The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis

Tuba Tülay Koca, (Sütçü İmam Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Kahramanmaraş, Türkiye)
MEHMET FATİH KORKMAZ, (Gelişim Üniversitesi, Tıp Fakültesi, Elit Tıp Merkezi Ortopedi ve Travmatoloji Anabilim Dalı, İstanbul, Türkiye)
Filiz ÖZDEMİR, (İnönü Üniversitesi, Sağlık Bilimleri Fakültesi, Fizyoterapi ve Rehabilitasyon Bölümü, Malatya, Türkiye)
Ejder Berk (Sütçü İmam Üniversitesi, Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Kahramanmaraş, Türkiye)
The European Research Journal
3 0
Yıl: 2019 Cilt: 5 Sayı: 1 Sayfa Aralığı: 98 - 103 Metin Dili: İngilizce DOI: 10.18621/eurj.376346 İndeks Tarihi: 16-04-2021

The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis

Öz:
Objective: Rheumatoid arthritis (RA) is a long-lasting autoimmune disorder that primarily affects the joints.Various biomarkers have been used for the prognosis and clinical follow-up. There are few studies that haveinvestigated whether or not neutrophil-lymphocyte ratio (NLR) and red cell distribution width (RDW) are goodindicators of systemic inflammation. The present study aims to explore the prognostic value of RDW and NLRin rheumatoid arthritis (RA) as a new inflammatory marker.Methods: RA patients (n = 124) who presented to the Rheumatology outpatient clinic in our hospital betweenMarch 2015 and May 2015 were included in this study retrospectively. As a first group, 47 clinically activeRA patients who had high acute phase proteins were included. In the second group, 73 clinically in-remissionRA patients who had normal acute phase proteins were included. Fifty-five healthy volunteers constituted thecontrol group.Results: The mean RDW was found to be 15.2 ± 2.9 in the active group; 14.6 ± 2 in the inactive group and13.4 ± 1.4 in the control group (p < 0.01). The mean NLR was found to be 3.7 ± 2.2 in the active group; 3.7 ±1.6 in the inactive group and 3.2 ± 0.9 in the control group (p = 0.190). There were statistically significantdifferences between the RDW values of the active-period RA patients with the control group (p < 0.01). Therewas statistically significant difference between RDW values of active RA and inactive RA patients (p < 0.01).The NLR results between the RA group and the control group (p = 0.700); the active RA group, and the inactiveRA group (p = 0.169) were similar. There was not statistically difference between the NLR values of activeRA patients with the control group (p = 0.360). There was statistically difference between the NLR values ofinactive RA patients with the control group (p = 0.047).Conclusion: RDW was found higher in all RA group than control, additionally was also higher in active RAgroup than remission group. NLR values of remission group was higher than control.
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APA Koca T, arslan a, özdemir f, BERK E (2019). The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. , 98 - 103. 10.18621/eurj.376346
Chicago Koca Tuba Tülay,arslan aydin,özdemir filiz,BERK EJDER The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. (2019): 98 - 103. 10.18621/eurj.376346
MLA Koca Tuba Tülay,arslan aydin,özdemir filiz,BERK EJDER The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. , 2019, ss.98 - 103. 10.18621/eurj.376346
AMA Koca T,arslan a,özdemir f,BERK E The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. . 2019; 98 - 103. 10.18621/eurj.376346
Vancouver Koca T,arslan a,özdemir f,BERK E The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. . 2019; 98 - 103. 10.18621/eurj.376346
IEEE Koca T,arslan a,özdemir f,BERK E "The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis." , ss.98 - 103, 2019. 10.18621/eurj.376346
ISNAD Koca, Tuba Tülay vd. "The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis". (2019), 98-103. https://doi.org/10.18621/eurj.376346
APA Koca T, arslan a, özdemir f, BERK E (2019). The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. The European Research Journal, 5(1), 98 - 103. 10.18621/eurj.376346
Chicago Koca Tuba Tülay,arslan aydin,özdemir filiz,BERK EJDER The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. The European Research Journal 5, no.1 (2019): 98 - 103. 10.18621/eurj.376346
MLA Koca Tuba Tülay,arslan aydin,özdemir filiz,BERK EJDER The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. The European Research Journal, vol.5, no.1, 2019, ss.98 - 103. 10.18621/eurj.376346
AMA Koca T,arslan a,özdemir f,BERK E The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. The European Research Journal. 2019; 5(1): 98 - 103. 10.18621/eurj.376346
Vancouver Koca T,arslan a,özdemir f,BERK E The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis. The European Research Journal. 2019; 5(1): 98 - 103. 10.18621/eurj.376346
IEEE Koca T,arslan a,özdemir f,BERK E "The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis." The European Research Journal, 5, ss.98 - 103, 2019. 10.18621/eurj.376346
ISNAD Koca, Tuba Tülay vd. "The importance of red cell distribution width and neutrophillymphocyte ratio as a new biomarker in rheumatoid arthritis". The European Research Journal 5/1 (2019), 98-103. https://doi.org/10.18621/eurj.376346
Sayfa Oluşturulma Tarihi
02-05-2024 6:38

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