Aim: Infections developing in the early phase of post transplant period may be life- threatening for patient under intense immunosuppression. Although urinary infections are the most frequently observed type of infections in this phase, infections in other systems are also needed to be evaluated in detail. In this study, we examined infections developing in the post- transplant period. Material and Method: In 306 patients who underwent renal transplantation, infections requiring hospitalization were retrospectively evaluated. These infections were studied in two periods. Results: In both periods, female patients (55.3%) developed infectious diseases more frequently compared to male patients. The median age of the patients is 35 (18-66) years. In the first period, surgical infections (25.9%), clinical sepsis (10.3%) and catheter infections (6.4%) were more frequently observed while urinary infections (46.7%), lower respiratory tract infections (16.1%), acute gastroenteritis (%16.1) and CMV infections (4.8%) were more frequently observed in the second period. Urinary infections were the most frequently observed type of infections in both periods (41.5% - 46.7%). The most common infectious factor was E.coli (64%) and GSBL synthesis rate was 51.4%. Conclusion: This study may contribute to the planning of empiric treatments in our hospital where post- transplant infections and their factors are observed.