TY  - JOUR
TI  - The relationship between atherogenic index of plasma and major risk factors of cardiovascular disease in obese and nonobese individuals
AB  - Objectives: Obesity is a health problem with gradually increasing prevalence and directly contribute to thedevelopment of cardiovascular disease (CVD). We aimed to investigate the relationship between atherogenicindex of plasma (AIP) and major risk factors of CVD in obese and non-obese individuals.Methods: This analytical case-control study was carried out on 501 individuals. Obese patients were includedin the case group and normal-overweight individuals were included in the control group. The groups weresimilar in terms of ages and gender. Detailed medical background of the participants was recorded andantropometric parameters were measured. High-density lipoprotein-cholesterol, low-density lipoproteincholesterol, total cholesterol, triglyceride, fasting blood glucose (FBG) and insulin were measured. AIP riskcategories were created according to published epidemiological data: AIP < 0.1 is associated with low risk,0.1-0.24 with moderate risk, and > 0.24 with high risk.Results: There was a statistically significant relationship between obesity, male gender, older age, smoking,insulin resistance, high waist circumference, elevation of the blood pressure, FBG and high CVD risk (p <0.005). CVD risk in males were 6.254 times more than in females [OR = 6.254, 95% CI; (2.287-17.107)],CVD risk in obese was 3.436 times more than in none-obese and CVD risk in individuals with insulin resistancewas 5.560-fold increase than individuals without insulin resistance [OR = 5.560, 95% CI; (3.069-10.070)] (p< 0.001).Conclusions: Our findings showed that increasing in AIP is associated with obesity and other cardiovascularrisk factors. Therefore, AIP can be used as a simple, economic and non invasive marker to identify for CVDrisk.
AU  - Kutlu, Ruhusen
AU  - KOCAK, Ahmet
AU  - SAYIN, SEHER
DO  - 10.18621/eurj.414561
PY  - 2019
JO  - The European Research Journal
VL  - 5
IS  - 4
SN  - 2149-3189
SP  - 678
EP  - 685
DB  - TRDizin
UR  - http://search/yayin/detay/405958
ER  -