A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine

azapağası, ebru; Fitoz, Ömer Suat; ince, erdal; KENDİRLİ, Tanıl; Özcan, Serhan; ÖZDEMİR, HALİL; TUNCER, Gökçen Öz

doi:10.24953/turkjped.2020.06.018

A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine

Ebru Azapağası, (Pediatric Intensive Care)

Tanıl Kendirli, (Pediatric Intensive Care)

Serhan Özcan, (Pediatric Intensive Care)

Gökçen Öz Tuncer, (Pediatric Neurology)

Halil Özdemir, (Pediatric Infection and)

Ömer Suat FİTÖZ, (Pediatric Radiology, Ankara University Faculty of Medicine, Ankara, Turkey.)

Erdal İnce (Pediatric Infection and)

Turkish Journal of Pediatrics

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Yıl: 2020 Cilt: 62 Sayı: 6 Sayfa Aralığı: 1058 - 1063 Metin Dili: İngilizce DOI: 10.24953/turkjped.2020.06.018 İndeks Tarihi: 30-04-2021

A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine

Öz:

Background. Streptococcus pneumonia is a cause of serious mortality and morbidity, especially among small children. However, currently, it causes lower rates of invasive infections due to successful vaccination programs.Case. We report an exceptional case of a 6-month-old child with meningoencephalitis caused by Streptococcus pneumonia despite the administration of two doses of pneumococcal conjugate vaccine (PCV). Meningitis progressed rapidly and led to widespread damage in parenchymal brain tissue with the emergence of fulminant meningoencephalitis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed widespread brain lesions, suggesting extensive parenchymal injury. Conclusion. Such diffuse white matter lesions among pediatric patients with Streptococcus pneumoniameningoencephalitis despite two doses of PCV have not been reported previously.

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APA	azapağası e, KENDİRLİ T, Özcan S, TUNCER G, ÖZDEMİR H, Fitoz Ö, ince e (2020). A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. , 1058 - 1063. 10.24953/turkjped.2020.06.018
Chicago	azapağası ebru,KENDİRLİ Tanıl,Özcan Serhan,TUNCER Gökçen Öz,ÖZDEMİR HALİL,Fitoz Ömer Suat,ince erdal A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. (2020): 1058 - 1063. 10.24953/turkjped.2020.06.018
MLA	azapağası ebru,KENDİRLİ Tanıl,Özcan Serhan,TUNCER Gökçen Öz,ÖZDEMİR HALİL,Fitoz Ömer Suat,ince erdal A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. , 2020, ss.1058 - 1063. 10.24953/turkjped.2020.06.018
AMA	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. . 2020; 1058 - 1063. 10.24953/turkjped.2020.06.018
Vancouver	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. . 2020; 1058 - 1063. 10.24953/turkjped.2020.06.018
IEEE	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e "A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine." , ss.1058 - 1063, 2020. 10.24953/turkjped.2020.06.018
ISNAD	azapağası, ebru vd. "A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine". (2020), 1058-1063. https://doi.org/10.24953/turkjped.2020.06.018

APA	azapağası e, KENDİRLİ T, Özcan S, TUNCER G, ÖZDEMİR H, Fitoz Ö, ince e (2020). A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. Turkish Journal of Pediatrics, 62(6), 1058 - 1063. 10.24953/turkjped.2020.06.018
Chicago	azapağası ebru,KENDİRLİ Tanıl,Özcan Serhan,TUNCER Gökçen Öz,ÖZDEMİR HALİL,Fitoz Ömer Suat,ince erdal A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. Turkish Journal of Pediatrics 62, no.6 (2020): 1058 - 1063. 10.24953/turkjped.2020.06.018
MLA	azapağası ebru,KENDİRLİ Tanıl,Özcan Serhan,TUNCER Gökçen Öz,ÖZDEMİR HALİL,Fitoz Ömer Suat,ince erdal A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. Turkish Journal of Pediatrics, vol.62, no.6, 2020, ss.1058 - 1063. 10.24953/turkjped.2020.06.018
AMA	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. Turkish Journal of Pediatrics. 2020; 62(6): 1058 - 1063. 10.24953/turkjped.2020.06.018
Vancouver	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine. Turkish Journal of Pediatrics. 2020; 62(6): 1058 - 1063. 10.24953/turkjped.2020.06.018
IEEE	azapağası e,KENDİRLİ T,Özcan S,TUNCER G,ÖZDEMİR H,Fitoz Ö,ince e "A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine." Turkish Journal of Pediatrics, 62, ss.1058 - 1063, 2020. 10.24953/turkjped.2020.06.018
ISNAD	azapağası, ebru vd. "A case of fulminant pneumococcus meningoencephalitisprogressing with white matter involvement despite twodoses of conjugated pneumococcus vaccine". Turkish Journal of Pediatrics 62/6 (2020), 1058-1063. https://doi.org/10.24953/turkjped.2020.06.018