TY  - JOUR
TI  - Headache as the sole presenting symptom of cerebral venous sinuses thrombosis: Subgroup analysis of data from the VENOST study
AB  - Objectives: Headache is the most common complaint in cerebral venous sinus thrombosis (CVST) and it may sometimes bethe only symptom in these patients. This retrospective and prospective study was an investigation of any differences in termsof clinical risk factors, radiological findings, or prognosis in patients with CVST who presented with isolated headache (IH) andcases with other concomitant findings (non-isolated headache [NIH]).Methods: A total of 1144 patients from a multicenter study of cerebral venous sinus thrombosis (VENOST study) were enrolled inthis research. The demographic, biochemical, clinical, and radiological aspects of 287 IH cases and 857 NIH cases were compared.Results: There were twice as many women as men in the study group. In the IH group, when gender distribution was evaluated byage group, no statistically significant difference was found. The onset of headache was frequently subacute and chronic in the IHgroup, but an acute onset was more common in the NIH group. Other neurological findings were observed in 29% of the IH groupduring follow-up. A previous history of deep, cerebral, or other venous thromboembolism was less common in the IH group thanin the NIH group. Transverse sinus involvement was greater in the IH group, whereas sagittal sinus involvement was greater in theNIH group. The presence of a plasminogen activator inhibitor (PAI) mutation was significantly greater in the IH group.Conclusion: IH and CVST should be kept in mind if a patient has subacute or chronic headache. PAI, which has an importantrole in thrombolytic events, may be a risk factor in CVST. Detailed hematological investigations should be considered. Additional studies are needed.
AU  - aytac, emrah
AU  - TOKUÇ, Firdevs Ezgi
AU  - Cabalar, Murat
AU  - Baybas, Sevim
AU  - Tascilar, Nida
AU  - Nazliel, Bijen
AU  - Necioglu Orken, Dilek
AU  - UGURLU, DERYA
AU  - Midi, Ipek
AU  - TEKGÖL UZUNER, GÜLNUR
AU  - Şenol, Mehmet Güney
AU  - OZDAG, Mehmet Fatih
AU  - Bakar, Mustafa
AU  - karahan, ali yavuz
AU  - ORUÇ, Serdar
AU  - Yesilot, Nilufer
AU  - Batur Caglayan, Hale
AU  - Sahin, Sevki
AU  - GÖKSEL, Karakurum Başak
AU  - MENGÜLLÜOĞLU, Necdet
AU  - kaplan, yuksel
AU  - İNCE, Birsen
AU  - ozaydin goksu, eylem
AU  - Yilmaz Kusbeci, Ozge
AU  - Küçükoğlu, Hayriye
AU  - Bektaş, Hesna
AU  - AÇIKGÖZ, Mustafa
AU  - Kozak, Hasan Hüseyin
AU  - mısırlı, cemile handan
AU  - UTKU, UYGAR
AU  - SUNGUR, Mehmet Ali
AU  - domac, fusun
AU  - Genç, Hamit
AU  - Ozturk, Serefnur
AU  - TEKELI, Hakan
AU  - Yayla, Vildan
AU  - ALUCLU, Mehmet Ufuk
AU  - ÇOLAKOĞLU, Sena
AU  - Yaman, Mehmet
AU  - Goksan, Baki
AU  - Yurekli, Vedat Ali
AU  - Demir, Serkan
AU  - DEMİRCİ, Seden
AU  - TÜFEKÇİ, AHMET
AU  - MİLANLIOĞLU, Aysel
AU  - KURUCU, HATICE
AU  - Afsar, Nazire
AU  - GÜNEŞ, TAŞKIN
AU  - Cinar, Nilgun
AU  - YILMAZ, ARDA
AU  - Uzuner, Nevzat
AU  - Yalın, Osman Özgür
AU  - Ekmekci, Hakan
AU  - Gökçe, Mustafa
AU  - DUMAN, Taşkın
DO  - 10.14744/agri.2020.77698
PY  - 2021
JO  - Ağrı
VL  - 33
IS  - 1
SN  - 1300-0012
SP  - 7
EP  - 14
DB  - TRDizin
UR  - http://search/yayin/detay/407460
ER  -