Yıl: 2020 Cilt: 31 Sayı: 2 Sayfa Aralığı: 163 - 168 Metin Dili: İngilizce DOI: 10.5606/ehc.2020.73458 İndeks Tarihi: 04-05-2021

Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study

Öz:
Objectives: This study aims to test the feasibility of the Fracture and Mortality Risk Evaluation (FAME) Index.Patients and methods: Two academic centers in Lithuania and Turkey participated in this retrospective study conducted between November 2018 and July 2019. A total of 100 consecutive patients (22 males, 78 females; mean age 78.9 years; range, 45 to 100 years) with low energy proximal femur fractures admitted for surgery were included in the study. Fracture Risk Assessment tool (FRAX) and the Sernbo scores were calculated and patients were classified into one of the nine subcategories of the FAME Index.Results: Demographics and FAME Index classifications were similar between centers. Patients with high risk of fracture and low risk of mortality accounted for 18% of all patients, which is the FAME Index subcategory to theoretically benefit from cancellous bone augmentation during internal fixation of a fragility hip fracture the most.Conclusion: The FAME Index was successfully applied in clinical emergency setting utilizing a simple form, and demonstrated promising potential in stratification of hip fractures most suitable for screw and device augmentation. Larger studies with at least one-year of follow-up are warranted to verify the validity of FAME Index.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Williamson S, Landeiro F, McConnell T, Fulford-Smith L, Javaid MK, Judge A, et al. Costs of fragility hip fractures globally: a systematic review and meta-regression analysis. Osteoporos Int 2017;28:2791-800.
  • 2. Chia PH, Gualano L, Seevanayagam S, Weinberg L. Outcomes following fractured neck of femurin an Australian metropolitan teaching hospital. Bone Joint Res 2013;2:162-8.
  • 3. Braithwaite RS, Col NF, Wong JB. Estimating hip fracture morbidity, mortality and costs. J Am Geriatr Soc 2003;51:364-70.
  • 4. Stravinskas M, Tarasevicius S, Laukaitis S, Nilsson M, Raina DB, Lidgren L. A ceramic bone substitute containing gentamicin gives good outcome in trochanteric hip fractures treated with dynamic hip screw and in revision of total hip arthroplasty: a case series. BMC Musculoskelet Disord 2018;19:438.
  • 5. Kammerlander C, Neuerburg C, Verlaan JJ, Schmoelz W, Miclau T, Larsson S. The use of augmentation techniques in osteoporotic fracture fixation. Injury 2016;47:S36-43.
  • 6. Compston J, Cooper A, Cooper C, Gittoes N, Gregson C, Harvey N, et al. UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos 2017;12:43.
  • 7. van Zeeland ML, Genovesi IP, Mulder JW, Strating PR, Glas AS, Engel AF. POSSUM predicts hospital mortality and long-term survival in patients with hip fractures. J Trauma 2011;70:E67-72.
  • 8. Wiles MD, Moran CG, Sahota O, Moppett IK. Nottingham Hip Fracture Score as a predictor of one year mortality in patients undergoing surgical repair of fractured neck of femur. Br J Anaesth 2011;106:501-4.
  • 9. Mellner C, Eisler T, Börsbo J, Brodén C, Morberg P, Mukka S. The Sernbo score predicts 1-year mortality after displaced femoral neck fractures treated with a hip arthroplasty. Acta Orthop 2017;88:402-6.
  • 10. Hernlund E, Svedbom A, Ivergård M, Compston J, Cooper C, Stenmark J, et al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 2013;8:136.
  • 11. Kaplan K, Miyamoto R, Levine BR, Egol KA, Zuckerman JD. Surgical management of hip fractures: an evidence-based review of the literature. II: intertrochanteric fractures. J Am Acad Orthop Surg 2008;16:665-73.
  • 12. Esen E, Dur H, Ataoğlu MB, Ayanoğlu T, Turanlı S. Evaluation of proximal femoral nail-antirotation and cemented, bipolar hemiarthroplasty with calcar replacement in treatment of intertrochanteric femoral fractures in terms of mortality and morbidity ratios. Eklem Hastalik Cerrahisi 2017;28:35-40.
  • 13. Kumar P, Rajnish RK, Sharma S, Dhillon MS. Proximal femoral nailing is superior to hemiarthroplasty in AO/OTA A2 and A3 intertrochanteric femur fractures in the elderly: a systematic literature review and meta-analysis. Int Orthop 2020;44:623-33.
  • 14. Li S, Chang SM, Niu WX, Ma H. Comparison of tip apex distance and cut-out complications between helical blades and lag screws in intertrochanteric fractures among the elderly: a meta-analysis. J Orthop Sci 2015;20:1062-9.
  • 15. Jiang J, Yang CH, Lin Q, Yun XD, Xia YY. Does arthroplasty provide better outcomes than internal fixation at mid- and long-term followup? A meta-analysis. Clin Orthop Relat Res 2015;473:2672-9.
  • 16. Mahmoud SS, Pearse EO, Smith TO, Hing CB. Outcomes of total hip arthroplasty, as a salvage procedure, following failed internal fixation of intracapsular fractures of the femoral neck: a systematic review and meta-analysis. Bone Joint J 2016;98-B:452-60.
  • 17. Goffin JM, Pankaj P, Simpson AH. The importance of lag screw position for the stabilization of trochanteric fractures with a sliding hip screw: a subject-specific finite element study. J Orthop Res 2013;31:596-600.
  • 18. Bozkurt HH, Atik OŞ, Tokgöz MA. Can distal radius or vertebra fractures due to low-energy trauma be a harbinger of a hip fracture? Eklem Hastalik Cerrahisi 2018;29:100-3.
  • 19. Ferrari S, Reginster JY, Brandi ML, Kanis JA, Devogelaer JP, Kaufman JM, et al. Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture. Arch Osteoporos 2016;11:37.
  • 20. Širka A, Raina DB, Isaksson H, Tanner KE, Smailys A, Kumar A, et al. Calcium Sulphate/Hydroxyapatite Carrier for Bone Formation in the Femoral Neck of Osteoporotic Rats. Tissue Eng Part A 2018. [Epub ahead of print]
  • 21. Raina DB, Larsson D, Sezgin EA, Isaksson H, Tägil M, Lidgren L. Biomodulation of an implant for enhanced bone-implant anchorage. Acta Biomater 2019;96:619-30.
  • 22. Kok J, Širka A, Grassi L, Raina DB, Tarasevičius Š, Tägil M, et al. Fracture strength of the proximal femur injected with a calcium sulfate/hydroxyapatite bone substitute. Clin Biomech (Bristol, Avon) 2019;63:172-8.
  • 23. Zhang R, Wang L, Lin Y, Yang M, Guo Z, Xia W, et al. A novel method for estimating nail-tract bone density for intertrochanteric fractures. J Orthop Translat 2018;18:40-7.
  • 24. Engelke K, Adams JE, Armbrecht G, Augat P, Bogado CE, Bouxsein ML, et al. Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions. J Clin Densitom 2008;11:123 - 62.
APA Sezgin E, Markeviciute V, Sirka A, Tarasevičius Š, Raina D, Isaksson H, Tägil M, Lidgren L (2020). Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. , 163 - 168. 10.5606/ehc.2020.73458
Chicago Sezgin Erdem Aras,Markeviciute Vetra,Sirka Aurimas,Tarasevičius Šarūnas,Raina Deepak Bushan,Isaksson Hanna,Tägil Magnus,Lidgren Lars Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. (2020): 163 - 168. 10.5606/ehc.2020.73458
MLA Sezgin Erdem Aras,Markeviciute Vetra,Sirka Aurimas,Tarasevičius Šarūnas,Raina Deepak Bushan,Isaksson Hanna,Tägil Magnus,Lidgren Lars Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. , 2020, ss.163 - 168. 10.5606/ehc.2020.73458
AMA Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. . 2020; 163 - 168. 10.5606/ehc.2020.73458
Vancouver Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. . 2020; 163 - 168. 10.5606/ehc.2020.73458
IEEE Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L "Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study." , ss.163 - 168, 2020. 10.5606/ehc.2020.73458
ISNAD Sezgin, Erdem Aras vd. "Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study". (2020), 163-168. https://doi.org/10.5606/ehc.2020.73458
APA Sezgin E, Markeviciute V, Sirka A, Tarasevičius Š, Raina D, Isaksson H, Tägil M, Lidgren L (2020). Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. Joint diseases and related surgery, 31(2), 163 - 168. 10.5606/ehc.2020.73458
Chicago Sezgin Erdem Aras,Markeviciute Vetra,Sirka Aurimas,Tarasevičius Šarūnas,Raina Deepak Bushan,Isaksson Hanna,Tägil Magnus,Lidgren Lars Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. Joint diseases and related surgery 31, no.2 (2020): 163 - 168. 10.5606/ehc.2020.73458
MLA Sezgin Erdem Aras,Markeviciute Vetra,Sirka Aurimas,Tarasevičius Šarūnas,Raina Deepak Bushan,Isaksson Hanna,Tägil Magnus,Lidgren Lars Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. Joint diseases and related surgery, vol.31, no.2, 2020, ss.163 - 168. 10.5606/ehc.2020.73458
AMA Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. Joint diseases and related surgery. 2020; 31(2): 163 - 168. 10.5606/ehc.2020.73458
Vancouver Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study. Joint diseases and related surgery. 2020; 31(2): 163 - 168. 10.5606/ehc.2020.73458
IEEE Sezgin E,Markeviciute V,Sirka A,Tarasevičius Š,Raina D,Isaksson H,Tägil M,Lidgren L "Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study." Joint diseases and related surgery, 31, ss.163 - 168, 2020. 10.5606/ehc.2020.73458
ISNAD Sezgin, Erdem Aras vd. "Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study". Joint diseases and related surgery 31/2 (2020), 163-168. https://doi.org/10.5606/ehc.2020.73458