TY  - JOUR
TI  - Endometrial scratching for poor responders basedon the Bologna criteria in ICSI fresh embryo transfercycles: a preliminary retrospective cohort study
AB  - Objective: This study evaluated the effect of endometrial injury on pregnancy outcomes in patients with a poor ovarian response (POR), based on the Bologna criteria, who underwent intracytoplasmic sperm injection (ICSI) cycles.Material and Methods: Sixty-eight patients were enrolled in this retrospective cohort study. All patients in the endometrial scratching group (group 1, n=32) and control group (group 2, n=36) underwent office hysteroscopy in the early follicular phase of the cycle before controlled ovarian stimulation. Group 1 also underwent endometrial scratching. The main outcome measure was the ongoing pregnancy rate.Results: The study groups had similar baseline demographics, including age, body mass index, duration of infertility, number of ICSI cycles, and hormone levels. However, the antral follicle count was significantly higher in group 1 than in group 2 (4.2±1.9 vs 3.3±1.8; p<0.05). There were no significant group differences in ovarian stimulation characteristics (ovarian stimulation time, trigger day endometrial thickness, number of metaphase II oocytes), number of embryos transferred, or the ratio of embryo transfer on days 3 and 5. Moreover, there were no significant differences between groups 1 and 2 in the rates of chemical pregnancy (25% vs 19.4%), clinical pregnancy (15.6% vs 11.1%) or ongoing pregnancy (9.4% vs 8.3%) (p>0.05 for all).Conclusion: Endometrial scratching did not improve pregnancy outcomes for patients meeting the Bologna criteria for a POR to ICSI cycles using fresh embryo transfer and the GnRH antagonist protocol. (J Turk Ger Gynecol Assoc 2021; 22: 47-52)
AU  - demir, mustafa
AU  - Yazıcıoğlu, Aslıhan
AU  - Kalyoncu, Şenol
DO  - 10.4274/jtgga.galenos.2021.2020.0127
PY  - 2021
JO  - Journal of the Turkish-German Gynecological Association
VL  - 22
IS  - 1
SN  - 1309-0399
SP  - 47
EP  - 52
DB  - TRDizin
UR  - http://search/yayin/detay/409231
ER  -