Yıl: 2020 Cilt: 27 Sayı: 9 Sayfa Aralığı: 2382 - 2385 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.04.410 İndeks Tarihi: 08-05-2021

Evaluation of oxidative stress in angiography workers

Öz:
Aim: In this study, we wanted to investigate the oxidative stress level and some antioxidant parameters in angiography workers exposed to high dose x-ray.Material and Methods: The study included 47 angiography workers and 50 healthy control group. Some antioxidant parameters (superoxide dismutase, catalase, and reduced glutathione) and levels of malondialdehyde, which is a marker of oxidative stress, were measured in the blood samples of all participants.Results: There was a significant increase in oxidative stress marker MDA levels and a significant decrease in antioxidant enzyme (superoxide dismutase, catalase and reduced glutathione) levels in all individuals of the study group compared to the control group (p<0.001 for all).Conclusion: Our results indicated that oxidative stress level increased and some antioxidant enzyme levels (superoxide dismutase, catalase and decreased glutathione) decreased in angiography workers exposed to long-term high-dose ionized radiation. We have linked this to the oxidant-antioxidant balance disorder caused by increased free radicals due to ionizing radiation, as noted in theliterature.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Dağdaş S. İyonlaştırıcı radyasyonlar ve kanser. Dicle Tıp Dergisi 2010;37:177-85.
  • 2. Neal R, Matthews RH, Lutz P, et al. Antioxidant role of N-acetyl cysteine isomers following high dose irradiation. Free Radic Biol Med 2003;34:689-95.
  • 3. Yan LJ. Positive oxidative stress in aging and agingrelated disease tolerance. Redox Biol 2014;2:165-9.
  • 4. Popov B, Gadjeva V, Valkanov P, et al. Lipid peroxidation, superoxide dismutase and catalase activities in brain tumor tissues. Arch Physiol Biochem 2003;111:455-9.
  • 5. Packer L. Methods in enzymology. Orlando: Academic Press; 1984.
  • 6. Beutler E, Kuhl W. Subunit structure of human hexosaminidase verified: interconvertibility of hexosaminidase isozymes. Nature 1975;258:262-4.
  • 7. Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995;41:1819-28.
  • 8. Freitinger Skalicka Z, Zolzer F, Beranek L, et al. Indicators of oxidative stress after ionizing and/ or non-ionizing radiation: superoxid dismutase and malondialdehyde. J Photochem Photobiol B 2012;117:111-4.
  • 9. Cooke MS, Evans MD, Dizdaroglu M, et al. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003;17:1195-214.
  • 10. Kovacic P, Somanathan R. Electromagnetic fields: mechanism, cell signaling, other bioprocesses, toxicity, radicals, antioxidants and beneficial effects. J Recept Signal Transduct Res 2010;30:214-26.
  • 11. Ceyhan AM, Akkaya VB, Gulecol SC, et al. Protective effects of β-glucan against oxidative injury induced by 2.45-GHz electromagnetic radiation in the skin tissue of rats. Arch Dermatol Res 2012;1-7.
  • 12. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128.
  • 13. Murray LJ, Granner DK, Mayes PA. Harper's Biochemistry. USA: McGraw-Hill Press; 2000.
  • 14. Akbari M, Ostadmohammadi V, Lankarani KB, et al. The Effects of Vitamin D Supplementation on Biomarkers of Inflammation and Oxidative Stress Among Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Horm Metab Res 2018;50:271-9.
  • 15. Al-Helaly LA, Ahmad TY. Oxidative Stress for X-Ray Diagnosis Workers in Mosul City. The Second Scientific Conference in Chemistry 2011;232-40.
  • 16. Celik H, Koyuncu I, Karakicik AZ, et al. Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments 2016;3:106-9.
  • 17. Malekirad AA, Ranjbar A, Rahzani K, et al. Oxidative stress in radiology staff. Environmental toxicology and pharmacology 2005;20:215-8.
  • 18. Doukali H, Ben Salah G, Hamdaoui L, et al. Oxidative stress and glutathione S-transferase genetic polymorphisms in medical staff professionally exposed to ionizing radiation. Int J Radiat Biol 2017;93:697-704.
  • 19. Yoshida T, Goto S, Kawakatsu M, et al. Mitochondrial dysfunction, a probable cause of persistent oxidative stress after exposure to ionizing radiation. Free Radic Res 2012;46:147-53.
  • 20. Simone NL, Soule BP, Ly D, et al. Ionizing radiationinduced oxidative stress alters miRNA expression. PLoS One 2009;4:e6377.
APA Gündüz A, DEMİR C (2020). Evaluation of oxidative stress in angiography workers. , 2382 - 2385. 10.5455/annalsmedres.2020.04.410
Chicago Gündüz Ali Mahir,DEMİR Canan Evaluation of oxidative stress in angiography workers. (2020): 2382 - 2385. 10.5455/annalsmedres.2020.04.410
MLA Gündüz Ali Mahir,DEMİR Canan Evaluation of oxidative stress in angiography workers. , 2020, ss.2382 - 2385. 10.5455/annalsmedres.2020.04.410
AMA Gündüz A,DEMİR C Evaluation of oxidative stress in angiography workers. . 2020; 2382 - 2385. 10.5455/annalsmedres.2020.04.410
Vancouver Gündüz A,DEMİR C Evaluation of oxidative stress in angiography workers. . 2020; 2382 - 2385. 10.5455/annalsmedres.2020.04.410
IEEE Gündüz A,DEMİR C "Evaluation of oxidative stress in angiography workers." , ss.2382 - 2385, 2020. 10.5455/annalsmedres.2020.04.410
ISNAD Gündüz, Ali Mahir - DEMİR, Canan. "Evaluation of oxidative stress in angiography workers". (2020), 2382-2385. https://doi.org/10.5455/annalsmedres.2020.04.410
APA Gündüz A, DEMİR C (2020). Evaluation of oxidative stress in angiography workers. Annals of Medical Research, 27(9), 2382 - 2385. 10.5455/annalsmedres.2020.04.410
Chicago Gündüz Ali Mahir,DEMİR Canan Evaluation of oxidative stress in angiography workers. Annals of Medical Research 27, no.9 (2020): 2382 - 2385. 10.5455/annalsmedres.2020.04.410
MLA Gündüz Ali Mahir,DEMİR Canan Evaluation of oxidative stress in angiography workers. Annals of Medical Research, vol.27, no.9, 2020, ss.2382 - 2385. 10.5455/annalsmedres.2020.04.410
AMA Gündüz A,DEMİR C Evaluation of oxidative stress in angiography workers. Annals of Medical Research. 2020; 27(9): 2382 - 2385. 10.5455/annalsmedres.2020.04.410
Vancouver Gündüz A,DEMİR C Evaluation of oxidative stress in angiography workers. Annals of Medical Research. 2020; 27(9): 2382 - 2385. 10.5455/annalsmedres.2020.04.410
IEEE Gündüz A,DEMİR C "Evaluation of oxidative stress in angiography workers." Annals of Medical Research, 27, ss.2382 - 2385, 2020. 10.5455/annalsmedres.2020.04.410
ISNAD Gündüz, Ali Mahir - DEMİR, Canan. "Evaluation of oxidative stress in angiography workers". Annals of Medical Research 27/9 (2020), 2382-2385. https://doi.org/10.5455/annalsmedres.2020.04.410