The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica

Eryılmaz, Fahri

doi:10.5455/annalsmedres.2020.04.312

The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica

Fahri ERYILMAZ (Sağlık Bakanlığı Hitit Üniversitesi Çorum Erol Olcok Eğitim ve Araştırma Hastanesi Nöroşirurji Kliniği, Çorum, Türkiye)

Annals of Medical Research

11 1

Yıl: 2020 Cilt: 27 Sayı: 9 Sayfa Aralığı: 2414 - 2420 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.04.312 İndeks Tarihi: 08-05-2021

The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica

Öz:

Aim: We aimed to determine C-reactive protein (CRP) levels in patients with intervertebral disc disease (IDD) and to evaluate these patients’ radiological and clinical characteristics.Material and Methods: A total of 102 patients were divided into four groups according to lumbar MRI results using the Macnab classification: bulging, protrusion, extrusion-sequestration, and normal. Straight leg raising test (SLR) and visual analogue scale (VAS) were used for clinical evaluation. Patients with bulging and protrusion were treated with conservative therapy within 5-10 days and bed-rest. Blood samples, SLR values and VAS scores were obtained from these patients before and after conservative therapy. The extrusion-sequestration group underwent lumbar spinal surgery. Medical treatment was not applied to this group and blood samples were collected only preoperatively. Individuals with normal MRI findings and no spinal complaints were evaluated as controls.Results: CRP levels were found to be 6.61 ± 7.78 in controls, 6.62 ± 5.28 in the bulging group, 11.50 ± 21.71 in the protrusion group and 17.18 ± 48.22 in the extruded-sequestration group (p=0.321). CRP levels were significantly decreased after treatment in the bulging group (p=0.001). Positive correlations were found between post-treatment VAS scores and pre-treatment WBC in theprotrusion group, and with CRP levels in the bulging group.Conclusion: Although no statistically significant difference was determined, we observed higher mean serum CRP levels in the surgical group (extrusion-sequestration). We believe that further studies must be performed to determine whether serum CRP levels can be used as a prognostic marker in surgical decision making.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Eryılmaz F (2020). The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. , 2414 - 2420. 10.5455/annalsmedres.2020.04.312
Chicago	Eryılmaz Fahri The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. (2020): 2414 - 2420. 10.5455/annalsmedres.2020.04.312
MLA	Eryılmaz Fahri The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. , 2020, ss.2414 - 2420. 10.5455/annalsmedres.2020.04.312
AMA	Eryılmaz F The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. . 2020; 2414 - 2420. 10.5455/annalsmedres.2020.04.312
Vancouver	Eryılmaz F The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. . 2020; 2414 - 2420. 10.5455/annalsmedres.2020.04.312
IEEE	Eryılmaz F "The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica." , ss.2414 - 2420, 2020. 10.5455/annalsmedres.2020.04.312
ISNAD	Eryılmaz, Fahri. "The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica". (2020), 2414-2420. https://doi.org/10.5455/annalsmedres.2020.04.312

APA	Eryılmaz F (2020). The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. Annals of Medical Research, 27(9), 2414 - 2420. 10.5455/annalsmedres.2020.04.312
Chicago	Eryılmaz Fahri The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. Annals of Medical Research 27, no.9 (2020): 2414 - 2420. 10.5455/annalsmedres.2020.04.312
MLA	Eryılmaz Fahri The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. Annals of Medical Research, vol.27, no.9, 2020, ss.2414 - 2420. 10.5455/annalsmedres.2020.04.312
AMA	Eryılmaz F The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. Annals of Medical Research. 2020; 27(9): 2414 - 2420. 10.5455/annalsmedres.2020.04.312
Vancouver	Eryılmaz F The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica. Annals of Medical Research. 2020; 27(9): 2414 - 2420. 10.5455/annalsmedres.2020.04.312
IEEE	Eryılmaz F "The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica." Annals of Medical Research, 27, ss.2414 - 2420, 2020. 10.5455/annalsmedres.2020.04.312
ISNAD	Eryılmaz, Fahri. "The importance of C-reactive protein levels for surgical decision-making and determination of response to conservative therapy in patients with acute sciatica". Annals of Medical Research 27/9 (2020), 2414-2420. https://doi.org/10.5455/annalsmedres.2020.04.312