TY  - JOUR
TI  - The Usefulness of Pleural Lactate Measurement for Differentiating Transudate and Exudate
AB  - Our study aimed to evaluate pleural lactate levels, to identify the reliability and validity of determining pleural fluid quality inpatients with pleural effusion.This is a prospective, observational study conducted on patients who were admitted to a universityhospital between July 1, 2017, and January 31, 2018, and diagnosed with pleural effusion. Pleural fluid classification into transudates and exudates was made according to Light’s criteria. The study group consisted of a total of 169 patients with pleural effusion,[99 (58.6%) male and aging 18-93 years (mean ± SD, 64.6 ± 16.1 years)]. Forty-four (26%) of the patients were evaluated as exudateand 125 (74%) as transudate. The median value of lactate was 3.20 mmol/L (min-max: 0.90-14.3) in exudate patients and 1.85mmol/L (min-max: 0.90-4.70) in transudate patients, and a significant difference was detected in the comparison of both (z: 5.894;p<0.001). There was a positive correlation between pleural lactate levels and pleural LDH, pleural LDH/serum LDH and pleuralprotein/serum protein ratios. The cut-off value of the pleural fluid lactate level was determined to be 2.0 for the highest sensitivityand specificity (sensitivity: 85%, specificity: 64%; AUC: 0.799). Measurement of lactate levels in pleural fluid can be useful for thedifferentiation of transudate and exudate fluid. Moreover, detection of lactate levels in a very short period may provide a moreuseful screening tool compared to other strategies.
AU  - KAYA, FILIZ
AU  - Canakci, Mustafa Emin
AU  - ozakin, engin
AU  - Struga, Genc
AU  - Yildirim, Huseyin
AU  - Acar, Nurdan
AU  - çevlik, rıdvan
DO  - 10.20515/otd.750745
PY  - 2021
JO  - Osmangazi Tıp Dergisi
VL  - 43
IS  - 3
SN  - 1305-4953
SP  - 217
EP  - 223
DB  - TRDizin
UR  - http://search/yayin/detay/411690
ER  -