Yıl: 2021 Cilt: 38 Sayı: 1 Sayfa Aralığı: 23 - 28 Metin Dili: İngilizce DOI: 10.4274/balkanmedj.galenos.2020.2020.2.153 İndeks Tarihi: 15-05-2021

Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit

Öz:
Background: Although Methicillin resistant Staphylococcus aureus (MRSA) is one of the major pathogens of healthcare associated infec-tions, we had only sporadic cases in our intensive care unit (ICU) for years.Aims: To investigate the sudden increase in the number of MRSA cases in ICU.Study design: Descriptive study.Methods: From the 5th December 2016 to 26th January 2017, we detected 11 new MRSA cases in ICU. Screening of 73 ICU healthcare workers (HCWs) and screening of 13 patients was performed for outbreak in-vestigation. Nine clinical isolates available in stocks and eight screening MRSA isolates were included in molecular studies. PFGE, spa-mecA-mecC-PVL in-house multiplex PCR assay and spa typing, SCCmec typing were performed for all isolates. Sequence type of the representative strain was determined by Multi-Locus Sequence typing (MLST). Results: All strains were mecA positive, PVL negative, and have the same antimicrobial susceptibility pattern except for two strains. All clinical, two patient screening and three nasal isolates of HCWs showed the same pulsotype, named clone A. The spa type of outbreak isolates is t030 and the SCCmec type is SCCmecIII; the MLST type of representative strain is ST239 (PFGE pulsotype A, ST239-SCC-mecIII-t030). Unrelated three isolates had PFGE pulsotype B-SC-CmecI-t030, PFGE pulsotype C-SCCmecIII-t459, PFGE pulsotype D-SCCmecIII. Conclusion: Molecular typing techniques are the cornerstones for the in-vestigation of outbreaks. Infection control measures, such as enhancing cleaning procedures, promoting hand hygiene, should be enforced in the ICU unit. All patients, including those who have already been discharged to other departments, must be put on contact isolation. HCWs carrying the MRSA strains could be offered decolonization.
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APA Bayraktar B, Gunduz A, ORYASIN E, Erdemir D, aktaş e, DURMAZ R, şen s, Uzun N, BOZDOGAN B (2021). Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. , 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
Chicago Bayraktar Banu,Gunduz Alper,ORYASIN ERMAN,Erdemir Duygu,aktaş elif,DURMAZ RIZA,şen selma,Uzun Nuray,BOZDOGAN BÜLENT Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. (2021): 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
MLA Bayraktar Banu,Gunduz Alper,ORYASIN ERMAN,Erdemir Duygu,aktaş elif,DURMAZ RIZA,şen selma,Uzun Nuray,BOZDOGAN BÜLENT Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. , 2021, ss.23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
AMA Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. . 2021; 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
Vancouver Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. . 2021; 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
IEEE Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B "Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit." , ss.23 - 28, 2021. 10.4274/balkanmedj.galenos.2020.2020.2.153
ISNAD Bayraktar, Banu vd. "Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit". (2021), 23-28. https://doi.org/10.4274/balkanmedj.galenos.2020.2020.2.153
APA Bayraktar B, Gunduz A, ORYASIN E, Erdemir D, aktaş e, DURMAZ R, şen s, Uzun N, BOZDOGAN B (2021). Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. Balkan Medical Journal, 38(1), 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
Chicago Bayraktar Banu,Gunduz Alper,ORYASIN ERMAN,Erdemir Duygu,aktaş elif,DURMAZ RIZA,şen selma,Uzun Nuray,BOZDOGAN BÜLENT Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. Balkan Medical Journal 38, no.1 (2021): 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
MLA Bayraktar Banu,Gunduz Alper,ORYASIN ERMAN,Erdemir Duygu,aktaş elif,DURMAZ RIZA,şen selma,Uzun Nuray,BOZDOGAN BÜLENT Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. Balkan Medical Journal, vol.38, no.1, 2021, ss.23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
AMA Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. Balkan Medical Journal. 2021; 38(1): 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
Vancouver Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit. Balkan Medical Journal. 2021; 38(1): 23 - 28. 10.4274/balkanmedj.galenos.2020.2020.2.153
IEEE Bayraktar B,Gunduz A,ORYASIN E,Erdemir D,aktaş e,DURMAZ R,şen s,Uzun N,BOZDOGAN B "Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit." Balkan Medical Journal, 38, ss.23 - 28, 2021. 10.4274/balkanmedj.galenos.2020.2020.2.153
ISNAD Bayraktar, Banu vd. "Early Detection and Control of Methicillin resistant Staphylococcus aureus Outbreak in an Intensive Care Unit". Balkan Medical Journal 38/1 (2021), 23-28. https://doi.org/10.4274/balkanmedj.galenos.2020.2020.2.153