Yıl: 2020 Cilt: 11 Sayı: 2 Sayfa Aralığı: 29 - 34 Metin Dili: İngilizce DOI: 10.18663/tjcl.648347 İndeks Tarihi: 20-05-2021

The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension

Öz:
Aim: Platelet to lymphocyte ratio (PLR) predicts worse outcome in cardiovascular disease. However data is limitted aboutthe role of PLR in the diurnal variation of hypertension. In this study we evaluated the relationship between the diurnalvariation of hypertension and PLR.Material and Methods: The study included a total of 247 essential hypertensive patients. All patients underwent 24-hour ambulatory blood monitoring. Thereafter hypertensive patients were divided into two groups: 64 dipper patients(30 female, mean age 53.8±12.9 years) and 38 non-dipper patients (18 female, mean age 52.6±12.5years). Completeblood count and biochemistry were measured by standard methods. PLR was measured by dividing platelet count tolymphocyte count.Results: Non-dipper hypertensives had signifi cantly higher PLR levels than dippers (127.9±32.16 vs 103.4±10.67, p<0.001).There was a negatif correlation between percentage of sistolic and diastolic blood pressure fall and PLR.Conclusion: We demonstrated that PLR, an inexpensive and easily accessible biomarker, is significantly higher innondipper hypertensives than the dipper hypertensives.
Anahtar Kelime:

Platelet lenfosit oranı ve hipertansiyonun diürnal ritmi arasındaki ilişki

Öz:
Amaç: Platelet lenfosit oranı (PLR) kardiyovasküler kötü sonlanımlar için öngördürücüdür. Ancak PLR’nın hipertansiyonun diürnal ritmindeki rolü ile ilgili veri sınırlıdır. Biz bu çalışmada PLR ile hipertansiyonun diürnal ritmi arasındaki ilişkiyi değerlendirmeyi amaçladık. Gereç ve Yöntemler: Çalışmaya toplamda 247 esansiyel hipertansiyon hastası dahil edildi. Tüm hastalara 24-saat ambulatuar kan basıncı monitorizasyonu yapıldı. Takiben hastalar iki gruba ayrıldı: 64 dipper hasta (30 kadın, ortalama yaş 53.8±12.9) ve 38 non-dipper hasta (18 kadın, ortalama yaş 52.6±12.5). Tam kan sayımı ve biyokimyasl değerlendirme standart metodlarla yapıldı. PLR platelet sayısının lenfosit sayısına bölünmesiyle hesaplandı. Bulgular: Nondipper hipertansifler dipper hipertansiflere kıyasla daha yüksek PLR’ye sahipti (127.9±32.16’e 103.4±10.67, p<0.001). Sistolik ve diastolik kan basıncının düşüş oranı ile PLR arasında negatif korelasyon mevcuttu. Sonuç: Ucuz ve kolay ulaşılabilir bir biobelirteç olan PLR, nondipper hipertansiflerde dipper hipertansiflere kyasla daha yüksektir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÇELEBİ S (2020). The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. , 29 - 34. 10.18663/tjcl.648347
Chicago ÇELEBİ Sevaş The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. (2020): 29 - 34. 10.18663/tjcl.648347
MLA ÇELEBİ Sevaş The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. , 2020, ss.29 - 34. 10.18663/tjcl.648347
AMA ÇELEBİ S The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. . 2020; 29 - 34. 10.18663/tjcl.648347
Vancouver ÇELEBİ S The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. . 2020; 29 - 34. 10.18663/tjcl.648347
IEEE ÇELEBİ S "The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension." , ss.29 - 34, 2020. 10.18663/tjcl.648347
ISNAD ÇELEBİ, Sevaş. "The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension". (2020), 29-34. https://doi.org/10.18663/tjcl.648347
APA ÇELEBİ S (2020). The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. Turkish Journal of Clinics and Laboratory, 11(2), 29 - 34. 10.18663/tjcl.648347
Chicago ÇELEBİ Sevaş The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. Turkish Journal of Clinics and Laboratory 11, no.2 (2020): 29 - 34. 10.18663/tjcl.648347
MLA ÇELEBİ Sevaş The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. Turkish Journal of Clinics and Laboratory, vol.11, no.2, 2020, ss.29 - 34. 10.18663/tjcl.648347
AMA ÇELEBİ S The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. Turkish Journal of Clinics and Laboratory. 2020; 11(2): 29 - 34. 10.18663/tjcl.648347
Vancouver ÇELEBİ S The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension. Turkish Journal of Clinics and Laboratory. 2020; 11(2): 29 - 34. 10.18663/tjcl.648347
IEEE ÇELEBİ S "The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension." Turkish Journal of Clinics and Laboratory, 11, ss.29 - 34, 2020. 10.18663/tjcl.648347
ISNAD ÇELEBİ, Sevaş. "The relationship between platelet to lymphocyte ratio and the diurnal variation of hypertension". Turkish Journal of Clinics and Laboratory 11/2 (2020), 29-34. https://doi.org/10.18663/tjcl.648347