Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey

Yıl: 2021 Cilt: 17 Sayı: 2 Sayfa Aralığı: 188 - 196 Metin Dili: İngilizce DOI: 10.4274/ejbh.galenos.2021.2021-1-4 İndeks Tarihi: 13-06-2021

Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey

Öz:
Objective: In early 2020, the spread of coronavirus disease-2019 (COVID-19) led the World Health Organization to declare this disease a pandemic. Initial epidemiological data showed that patients with cancer were at high risk of developing severe forms of COVID-19. National scientific societies published recommendations modifying the patients’ breast cancer (BC) management to preserve, in theory, quality oncologic care, avoiding the increased risk of contamination. The Senology International Society (SIS) decided to take an inventory of the actions taken worldwide. This study investigates COVID-19-related changes concerning BC management and analyzes the will to maintain them after the pandemic, evaluating their oncological safety consequences. Materials and Methods: SIS network members participated in an online survey using a questionnaire (Microsoft® Forms) from June 15th to July 31st, 2020. Results: Forty-five responses from 24 countries showed that screening programs had been suspended (68%); magnetic resonance imagines were postponed (73%); telemedicine was preferred when possible (71%). Surgeries were postponed: reconstructive (77%), for benign diseases (84%), and in patients with significant comorbidities (66%). Chemotherapy and radiotherapy protocols had been adapted in 28% of patients in both. Exception for telemedicine (34%), these changes in practice should not be continued. Conclusion: The SIS survey showed significant changes in BC’s diagnosis and treatment during the first wave of the COVID-19 pandemic, but most of these changes should not be maintained. Indeed, women have fewer severe forms of COVID-19 and are less likely to die than men. The risk of dying from COVID-19 is more related to the presence of comorbidities and age than to BC. Stopping screening and delaying treatment leads to more advanced stages of BC. Only women aged over 65 with BC under treatment and comorbidities require adaptation of their cancer management.
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  • 1. Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol 2020; 21: 335-337. (PMID: 32066541) [Crossref]
  • 2. Miyashita H, Mikami T, Chopra N, Yamada T, Chernyavsky S, Rizk D, et al. Do patients with cancer have a poorer prognosis of COVID-19? An experience in New York City. Ann Oncol 2020; 31: 1088-1089. (PMID: 32330541) [Crossref]
  • 3. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68: 394-424. (PMID: 30207593) [Crossref]
  • 4. Darai E, Mathelin C, Gligorov J. Breast cancer management during the COVID 19 pandemic: French guidelines. Eur J Breast Health 2020; 16: 160-161. (PMID: 32656513) [Crossref]
  • 5. Soran A, Gimbel M, Diego E. Breast cancer diagnosis, treatment and follow-up during COVID-19 pandemic. Eur J Breast Health 2020; 16: 86-88. (PMID: 32285027) [Crossref]
  • 6. Cakmak GK, Ozmen V. Sars-CoV-2 (COVID-19) outbreak and breast cancer surgery in Turkey. Eur J Breast Health 2020; 16: 83-85. (PMID: 32285026) [Crossref]
  • 7. Fu L, Wang B, Yuan T, Chen X, Ao Y, Fitzpatrick T, et al. Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: a systematic review and meta-analysis. J Infect 2020; 80: 656-665. (PMID: 32283155) [Crossref]
  • 8. de Azambuja E, Brandão M, Wildiers H, Laenen A, Aspeslagh S, Fontaine C, et al. Impact of solid cancer on in-hospital mortality overall and among different subgroups of patients with COVID-19: a nationwide, population-based analysis. ESMO Open 2020; 5: e000947. doi: 10.1136/ esmoopen-2020-000947. (PMID: 32978251) [Crossref]
  • 9. de Azambuja E, Trapani D, Loibl S, Delaloge S, Senkus E, Criscitiello C, et al. ESMO Management and treatment adapted recommendations in the COVID-19 era: breast cancer. ESMO Open 2020; 5(Suppl 3): e000793. doi: 10.1136/esmoopen-2020-000793. (PMID: 32439716) [Crossref]
  • 10. Seely JM, Scaranelo AM, Yong-Hing C, Appavoo S, Flegg C, Kulkarni S, et al. COVID-19: safe guidelines for breast imaging during the pandemic. Can Assoc Radiol J 2020; 71: 459-469. (PMID: 32452700) [Crossref]
  • 11. Lin DD, Meghal T, Murthy P, Mo L, D’Silva A, Huang Y, et al. Chemotherapy treatment modifications during the COVID-19 outbreak at a Community Cancer Center in New York City. JCO Glob Oncol 2020: 1298-1305. (PMID: 32795196) [Crossref]
  • 12. Spencer K, Jones CM, Girdler R, Roe C, Sharpe M, Lawton S, et al. The impact of the COVID-19 pandemic on radiotherapy services in England, UK: a population-based study. Lancet Oncol 2021; 22: 309-320. (PMID: 33493433) [Crossref]
  • 13. Park KU, Gregory ME, Lustberg MB, Bazan JG, Shen C, Rosenberg SM, et al. Abstract SS2-05: emerging from COVID-19 pandemic: provider perspective on use of neoadjuvant endocrine therapy (NET) in early stage hormone receptor positive breast cancer. Cancer Res 2021; 81(Suppl 4): SS2-05-SS2-. [Crossref]
  • 14. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395: 507- 513. (PMID: 32007143) [Crossref]
  • 15. Gebhard C, Regitz-Zagrosek V, Neuhauser HK, Morgan R, Klein SL. Impact of sex and gender on COVID-19 outcomes in Europe. Biol Sex Differ 2020; 11: 29. (PMID: 32450906 ) [Crossref]
  • 16. Meng Y, Wu P, Lu W, Liu K, Ma K, Huang L, et al. Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: a retrospective study of 168 severe patients. PLoS Pathog 2020; 16:e1008520. doi: 10.1371/journal.ppat.1008520. (PMID: 3234374) [Crossref]
  • 17. Global Health 5050. The Covid-19 sex-disaggredated data tracker. Available from: https://globalhealth5050.org/2020 [Crossref]
  • 18. Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, et al. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature 2020; 588: 315-320. (PMID: 32846427) [Crossref]
  • 19. Lee LY, Cazier JB, Angelis V, Arnold R, Bisht V, Campton NA, et al. COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study. Lancet 2020; 395: 1919-1926. (PMID: 3247368) [Crossref]
  • 20. Vuagnat P, Frelaut M, Ramtohul T, Basse C, Diakite S, Noret A, et al. COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area. Breast Cancer Res 2020; 22: 55. (PMID: 32460829) [Crossref]
  • 21. Kalinsky K, Accordino MK, Hosi K, Hawley JE, Trivedi MS, Crew KD, et al. Characteristics and outcomes of patients with breast cancer diagnosed with SARS-Cov-2 infection at an academic center in New York City. Breast Cancer Res Treat 2020; 182: 239-242. (PMID: 32405915) [Crossref]
  • 22. de Melo AC, Thuler LCS, da Silva JL, de Albuquerque LZ, Pecego AC, Rodrigues LOR, et al. Cancer inpatients with COVID-19: a report from the Brazilian National Cancer Institute. PLoS One 2020; 15: e0241261. doi: 10.1371/journal.pone.0241261. (PMID: 33104715) [Crossref]
  • 23. Vanni G, Tazzioli G, Pellicciaro M, Materazzo M, Paolo O, Cattadori F, et al. Delay in breast cancer treatments during the first COVID-19 lockdown. a multicentric analysis of 432 Patients. Anticancer Res 2020; 40: 7119-7125. (PMID: 33288611) [Crossref]
  • 24. Maringe C, Spicer J, Morris M, Purushotham A, Nolte E, Sullivan R, et al. The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study. Lancet Oncol 2020; 21: 1023-1034. (PMID: 32702310) [Crossref]
  • 25. Johnson BA, Waddimba AC, Ogola GO, Fleshman JW, Jr., Preskitt JT. A systematic review and meta-analysis of surgery delays and survival in breast, lung and colon cancers: implication for surgical triage during the COVID-19 pandemic. Am J Surg 2020; S0002-9610(20)30793-5. doi: 10.1016/j.amjsurg.2020.12.015. (PMID: 33317814) [Crossref]
  • 26. Francescangeli F, De Angelis ML, Zeuner A. COVID-19: a potential driver of immune-mediated breast cancer recurrence? Breast Cancer Res 2020; 22: 117. (PMID: 33126915) [Crossref]
  • 27. Silvin A, Chapuis N, Dunsmore G, Goubet AG, Dubuisson A, Derosa L, et al. Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19. Cell 2020; 182: 1401-18 e18. doi: 10.1016/j.cell.2020.08.002. (PMID: 32810439) [Crossref]
APA MATHELIN C, Natarajan-Amé S, Anyanwu S, Avisar E, BOUBNIDER W, BREITLING K, Ayettey Anie H, CONCEİÇAO J, DUPONT V, Elder E, Elfgen C, ELONGE T, IGLESIAS E, Imoto S, Ioannidou-Mouzaka L, Kappos E, KAUFMANN M, KNAUER M, LUZUY F, Margaritoni M, MBODJ M, Mundinger A, ORDA R, Ostapenko V, OZBAS S, Ozmen V, Pagani O, Pienkowski T, Schneebaum s, SHMALTS E, SELIM A, PAVEL Z, LODI M, Magalhães Costa M (2021). Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. , 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
Chicago MATHELIN Carole,Natarajan-Amé Shanti,Anyanwu Stanley,Avisar Eli,BOUBNIDER Wahib Mohcen,BREITLING Katrin,Ayettey Anie Hannah,CONCEİÇAO Jos Carlos,DUPONT Veronique,Elder Elisabeth,Elfgen Constanze,ELONGE Tony,IGLESIAS Edelmiro,Imoto Shigeru,Ioannidou-Mouzaka Lydia,Kappos Elisabeth,KAUFMANN Martin,KNAUER Michael,LUZUY Franck,Margaritoni Marko,MBODJ Mamadou,Mundinger Alexander,ORDA Ruben,Ostapenko Valerijus,OZBAS SERDAR,Ozmen Vahit,Pagani Olivia,Pienkowski Tadeusz,Schneebaum schlomo,SHMALTS Ekaterina,SELIM ASHRAF,PAVEL Zotov,LODI Massimo,Magalhães Costa Mauricio Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. (2021): 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
MLA MATHELIN Carole,Natarajan-Amé Shanti,Anyanwu Stanley,Avisar Eli,BOUBNIDER Wahib Mohcen,BREITLING Katrin,Ayettey Anie Hannah,CONCEİÇAO Jos Carlos,DUPONT Veronique,Elder Elisabeth,Elfgen Constanze,ELONGE Tony,IGLESIAS Edelmiro,Imoto Shigeru,Ioannidou-Mouzaka Lydia,Kappos Elisabeth,KAUFMANN Martin,KNAUER Michael,LUZUY Franck,Margaritoni Marko,MBODJ Mamadou,Mundinger Alexander,ORDA Ruben,Ostapenko Valerijus,OZBAS SERDAR,Ozmen Vahit,Pagani Olivia,Pienkowski Tadeusz,Schneebaum schlomo,SHMALTS Ekaterina,SELIM ASHRAF,PAVEL Zotov,LODI Massimo,Magalhães Costa Mauricio Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. , 2021, ss.188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
AMA MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. . 2021; 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
Vancouver MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. . 2021; 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
IEEE MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M "Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey." , ss.188 - 196, 2021. 10.4274/ejbh.galenos.2021.2021-1-4
ISNAD MATHELIN, Carole vd. "Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey". (2021), 188-196. https://doi.org/10.4274/ejbh.galenos.2021.2021-1-4
APA MATHELIN C, Natarajan-Amé S, Anyanwu S, Avisar E, BOUBNIDER W, BREITLING K, Ayettey Anie H, CONCEİÇAO J, DUPONT V, Elder E, Elfgen C, ELONGE T, IGLESIAS E, Imoto S, Ioannidou-Mouzaka L, Kappos E, KAUFMANN M, KNAUER M, LUZUY F, Margaritoni M, MBODJ M, Mundinger A, ORDA R, Ostapenko V, OZBAS S, Ozmen V, Pagani O, Pienkowski T, Schneebaum s, SHMALTS E, SELIM A, PAVEL Z, LODI M, Magalhães Costa M (2021). Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. European Journal of Breast Health, 17(2), 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
Chicago MATHELIN Carole,Natarajan-Amé Shanti,Anyanwu Stanley,Avisar Eli,BOUBNIDER Wahib Mohcen,BREITLING Katrin,Ayettey Anie Hannah,CONCEİÇAO Jos Carlos,DUPONT Veronique,Elder Elisabeth,Elfgen Constanze,ELONGE Tony,IGLESIAS Edelmiro,Imoto Shigeru,Ioannidou-Mouzaka Lydia,Kappos Elisabeth,KAUFMANN Martin,KNAUER Michael,LUZUY Franck,Margaritoni Marko,MBODJ Mamadou,Mundinger Alexander,ORDA Ruben,Ostapenko Valerijus,OZBAS SERDAR,Ozmen Vahit,Pagani Olivia,Pienkowski Tadeusz,Schneebaum schlomo,SHMALTS Ekaterina,SELIM ASHRAF,PAVEL Zotov,LODI Massimo,Magalhães Costa Mauricio Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. European Journal of Breast Health 17, no.2 (2021): 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
MLA MATHELIN Carole,Natarajan-Amé Shanti,Anyanwu Stanley,Avisar Eli,BOUBNIDER Wahib Mohcen,BREITLING Katrin,Ayettey Anie Hannah,CONCEİÇAO Jos Carlos,DUPONT Veronique,Elder Elisabeth,Elfgen Constanze,ELONGE Tony,IGLESIAS Edelmiro,Imoto Shigeru,Ioannidou-Mouzaka Lydia,Kappos Elisabeth,KAUFMANN Martin,KNAUER Michael,LUZUY Franck,Margaritoni Marko,MBODJ Mamadou,Mundinger Alexander,ORDA Ruben,Ostapenko Valerijus,OZBAS SERDAR,Ozmen Vahit,Pagani Olivia,Pienkowski Tadeusz,Schneebaum schlomo,SHMALTS Ekaterina,SELIM ASHRAF,PAVEL Zotov,LODI Massimo,Magalhães Costa Mauricio Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. European Journal of Breast Health, vol.17, no.2, 2021, ss.188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
AMA MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. European Journal of Breast Health. 2021; 17(2): 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
Vancouver MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey. European Journal of Breast Health. 2021; 17(2): 188 - 196. 10.4274/ejbh.galenos.2021.2021-1-4
IEEE MATHELIN C,Natarajan-Amé S,Anyanwu S,Avisar E,BOUBNIDER W,BREITLING K,Ayettey Anie H,CONCEİÇAO J,DUPONT V,Elder E,Elfgen C,ELONGE T,IGLESIAS E,Imoto S,Ioannidou-Mouzaka L,Kappos E,KAUFMANN M,KNAUER M,LUZUY F,Margaritoni M,MBODJ M,Mundinger A,ORDA R,Ostapenko V,OZBAS S,Ozmen V,Pagani O,Pienkowski T,Schneebaum s,SHMALTS E,SELIM A,PAVEL Z,LODI M,Magalhães Costa M "Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey." European Journal of Breast Health, 17, ss.188 - 196, 2021. 10.4274/ejbh.galenos.2021.2021-1-4
ISNAD MATHELIN, Carole vd. "Breast Cancer Management During the COVID-19 Pandemic: The Senologic International Society Survey". European Journal of Breast Health 17/2 (2021), 188-196. https://doi.org/10.4274/ejbh.galenos.2021.2021-1-4