Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats

Objective: The worldwide incidence of a gastric ulcer is high, most often as a result of useof nonsteroidal anti-inflammatory drugs, excessive alcohol consumption, or Helicobacterpylori infection. An ethanol-based gastric ulcer model in rats was used to examine the effectof persimmon (Diospyros kaki L.) extract as a potential form of treatment.Methods: Two dosages of persimmon extract were applied in a gastric ulcer model createdwith 5 mL/kg ethanol in Wistar albino rats. Histopathological and biochemical methods wereused to assess any gastroprotective effects.Results: Persimmon extract significantly decreased the level of the cytokines interleukin(IL)-10, IL-6, tumor necrosis factor alpha (TNF-α) and IL-1 beta. Caspase-3 and nuclearfactor kappa B expression was also significantly reduced.Conclusion: Persimmon fruit extract demonstrated a gastroprotective effect in an ethanol-based gastric ulcer model in rats.

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APA	guler m, tanyeli a, Eraslan E, Bozhuyuk M, Ekinci Akdemir F, TOKAY E, KURT N, Capanoglu E, Özkan G (2021). Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. , 1 - 7. 10.14744/scie.2020.94546
Chicago	guler mustafa can,tanyeli ayhan,Eraslan Ersen,Bozhuyuk Mehmet Ramazan,Ekinci Akdemir Fazile Nur,TOKAY Erdem,KURT Nezahat,Capanoglu Esra,Özkan Gülay Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. (2021): 1 - 7. 10.14744/scie.2020.94546
MLA	guler mustafa can,tanyeli ayhan,Eraslan Ersen,Bozhuyuk Mehmet Ramazan,Ekinci Akdemir Fazile Nur,TOKAY Erdem,KURT Nezahat,Capanoglu Esra,Özkan Gülay Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. , 2021, ss.1 - 7. 10.14744/scie.2020.94546
AMA	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. . 2021; 1 - 7. 10.14744/scie.2020.94546
Vancouver	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. . 2021; 1 - 7. 10.14744/scie.2020.94546
IEEE	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G "Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats." , ss.1 - 7, 2021. 10.14744/scie.2020.94546
ISNAD	guler, mustafa can vd. "Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats". (2021), 1-7. https://doi.org/10.14744/scie.2020.94546

APA	guler m, tanyeli a, Eraslan E, Bozhuyuk M, Ekinci Akdemir F, TOKAY E, KURT N, Capanoglu E, Özkan G (2021). Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. Southern Clinics of Istanbul Eurasia, 32(1), 1 - 7. 10.14744/scie.2020.94546
Chicago	guler mustafa can,tanyeli ayhan,Eraslan Ersen,Bozhuyuk Mehmet Ramazan,Ekinci Akdemir Fazile Nur,TOKAY Erdem,KURT Nezahat,Capanoglu Esra,Özkan Gülay Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. Southern Clinics of Istanbul Eurasia 32, no.1 (2021): 1 - 7. 10.14744/scie.2020.94546
MLA	guler mustafa can,tanyeli ayhan,Eraslan Ersen,Bozhuyuk Mehmet Ramazan,Ekinci Akdemir Fazile Nur,TOKAY Erdem,KURT Nezahat,Capanoglu Esra,Özkan Gülay Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. Southern Clinics of Istanbul Eurasia, vol.32, no.1, 2021, ss.1 - 7. 10.14744/scie.2020.94546
AMA	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. Southern Clinics of Istanbul Eurasia. 2021; 32(1): 1 - 7. 10.14744/scie.2020.94546
Vancouver	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats. Southern Clinics of Istanbul Eurasia. 2021; 32(1): 1 - 7. 10.14744/scie.2020.94546
IEEE	guler m,tanyeli a,Eraslan E,Bozhuyuk M,Ekinci Akdemir F,TOKAY E,KURT N,Capanoglu E,Özkan G "Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats." Southern Clinics of Istanbul Eurasia, 32, ss.1 - 7, 2021. 10.14744/scie.2020.94546
ISNAD	guler, mustafa can vd. "Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in Rats". Southern Clinics of Istanbul Eurasia 32/1 (2021), 1-7. https://doi.org/10.14744/scie.2020.94546