The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients
Yıl: 2021 Cilt: 5 Sayı: 1 Sayfa Aralığı: 89 - 94 Metin Dili: İngilizce DOI: 10.14744/ejmi.2020.39466 İndeks Tarihi: 18-06-2021
The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients
Öz: Objectives: Malignant pleural mesothelioma (MPM) accounts for approximately 80% of all mesothelioma cases.Methods: Forty-three patients diagnosed with advanced MPM were included in our study. We aimed to investigatefirst-line therapy options and the importance of platinum sensitivity in patients diagnosed with MPM, who were denovo metastatic or progressed from the early to the metastatic stage.Results: The mean age of the patients was 58.8±11.7 years, and 58.1% (25 patients) were male. The median overall survival (OS) was found to be 10.5 months (CI 95% 5.8-15.2). Median progression-free survival (PFS) of all MPMpatients was 7.6 months (CI 95% 6.2-7.9). When comparing the platinum-sensitive group to the platinum-resistantgroup, the median OS of the platinum-sensitive group was found to be 10.5 months (CI 95% 4.6-16.5), and the median OS of the platinum-resistant group was 3.3 months (CI 95% 3.1-3.6) (p=0.02). The median PFS of the platinumsensitive group was 7.9 months (CI 95% 5.9-9.9), while that for the platinum-resistant group was 2.4 months (CI 95%2.1-2.8) (p<0.01).Conclusion: Platinum-based chemotherapy regimens should be considered first at the metastatic stage.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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| APA | Ocak B, Şahin A, Dakiki B, Odman H, saydam n, Oyucu Orhan S, KACAN T, deligonul a, cubukcu e, Evrensel T (2021). The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. , 89 - 94. 10.14744/ejmi.2020.39466 |
| Chicago | Ocak Birol,Şahin Ahmet Bilgehan,Dakiki Bahar,Odman Hikmet utku,saydam neslihan hazel,Oyucu Orhan Sibel,KACAN Turgut,deligonul adem,cubukcu erdem,Evrensel Turkkan The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. (2021): 89 - 94. 10.14744/ejmi.2020.39466 |
| MLA | Ocak Birol,Şahin Ahmet Bilgehan,Dakiki Bahar,Odman Hikmet utku,saydam neslihan hazel,Oyucu Orhan Sibel,KACAN Turgut,deligonul adem,cubukcu erdem,Evrensel Turkkan The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. , 2021, ss.89 - 94. 10.14744/ejmi.2020.39466 |
| AMA | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. . 2021; 89 - 94. 10.14744/ejmi.2020.39466 |
| Vancouver | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. . 2021; 89 - 94. 10.14744/ejmi.2020.39466 |
| IEEE | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T "The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients." , ss.89 - 94, 2021. 10.14744/ejmi.2020.39466 |
| ISNAD | Ocak, Birol vd. "The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients". (2021), 89-94. https://doi.org/10.14744/ejmi.2020.39466 |
| APA | Ocak B, Şahin A, Dakiki B, Odman H, saydam n, Oyucu Orhan S, KACAN T, deligonul a, cubukcu e, Evrensel T (2021). The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. Eurasian Journal of Medical Investigation, 5(1), 89 - 94. 10.14744/ejmi.2020.39466 |
| Chicago | Ocak Birol,Şahin Ahmet Bilgehan,Dakiki Bahar,Odman Hikmet utku,saydam neslihan hazel,Oyucu Orhan Sibel,KACAN Turgut,deligonul adem,cubukcu erdem,Evrensel Turkkan The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. Eurasian Journal of Medical Investigation 5, no.1 (2021): 89 - 94. 10.14744/ejmi.2020.39466 |
| MLA | Ocak Birol,Şahin Ahmet Bilgehan,Dakiki Bahar,Odman Hikmet utku,saydam neslihan hazel,Oyucu Orhan Sibel,KACAN Turgut,deligonul adem,cubukcu erdem,Evrensel Turkkan The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. Eurasian Journal of Medical Investigation, vol.5, no.1, 2021, ss.89 - 94. 10.14744/ejmi.2020.39466 |
| AMA | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. Eurasian Journal of Medical Investigation. 2021; 5(1): 89 - 94. 10.14744/ejmi.2020.39466 |
| Vancouver | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients. Eurasian Journal of Medical Investigation. 2021; 5(1): 89 - 94. 10.14744/ejmi.2020.39466 |
| IEEE | Ocak B,Şahin A,Dakiki B,Odman H,saydam n,Oyucu Orhan S,KACAN T,deligonul a,cubukcu e,Evrensel T "The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients." Eurasian Journal of Medical Investigation, 5, ss.89 - 94, 2021. 10.14744/ejmi.2020.39466 |
| ISNAD | Ocak, Birol vd. "The Importance of Platinum Sensitivity in Metastatic Malignant Pleural Mesothelioma Patients". Eurasian Journal of Medical Investigation 5/1 (2021), 89-94. https://doi.org/10.14744/ejmi.2020.39466 |
