TY  - JOUR
TI  - Repeated dose of prostaglandin E2 vaginal insert when the first dose fails
AB  - Objective: To compare the obstetric and neonatal outcomes of patients treated with repeated-dose prostaglandin E2 (dinoprostone) vaginal insert whenthe first dose fails.Materials and Methods: This retrospective study included 1.043 pregnant women who received dinoprostone for labor induction between November2012 and August 2015. Pregnant women were divided into two groups according to the number of dinoprostone administrations: group 1, single-dosedinoprostone (n=1.000), and group 2, repeated-dose dinoprostone (n=43). Intrapartum, postpartum, and neonatal outcomes of the pregnant women werecompared.Results: Vaginal delivery rate was 65% in group 1 and 30.2% in group 2 (p=0.001). The need for the neonatal intensive care unit was found in 44 pregnantwomen (4.4%) in group 1 and 6 pregnant women (13.6%) in group 2 (p=0.006).Conclusion: When obstetric and neonatal data were evaluated in our study, we observed that dinoprostone administration was associated with increasedcesarean rates and adverse neonatal outcomes with repeated-dose dinoprostone when the first dose failed.
AU  - Karadag, Ceyda
AU  - Esin, Sertac
AU  - Yalvaç, Ethem Serdar
AU  - Karadag, Burak
AU  - Basar, Tugrul
AU  - Tohma, Yusuf Aytaç
DO  - 10.4274/tjod.galenos.2021.34119
PY  - 2021
JO  - Turkish Journal of Obstetrics and Gynecology
VL  - 18
IS  - 1
SN  - 2149-9322
SP  - 50
EP  - 55
DB  - TRDizin
UR  - http://search/yayin/detay/425279
ER  -