TY  - JOUR
TI  - THE MOST USEFUL MARKER FOR THE DIAGNOSIS OF ACUTE APPENDICITIS: SERUM AMYLOID-A
AB  - Objective: Leukocytosis and high CRP levels which are used in the diagnosis of acute appendicitis may be insufficient to support the diagnosis ofrecurrent infections in children. The objective of our study was to evaluate the Serum Amyloid A protein (SAA) levels in children with confirmedacute appendicitis and to compare the sensitivity and specificity of this marker of inflammation with WBC and CRP.Methods: Sixty nine children (27 girls, 42 boys) who were admitted to the emergency service with abdominal pain were included in the study.Patients were divided into three groups as follows; Group­I: Patients with acute abdomen was operated with pre­diagnosis of acute appendicitis;Group­II: Patients who were hospitalized with the diagnosis of acute abdominal pain, but not operated; Group C: Patients who applied to emergencyservice for reasons other than acute abdominal pain, and cared for amyloid levels. The blood serum SAA, ESR, CRP and WBC at first admission, 6thhours, and 24th hours were measured and compared.Results: In first admission, at the 6th and 24th hours SAA and CRP levels were significantly higher in Group­I when compared with Group­II andGroup­C (p<0.001, p<0.05, respectively). There was no statistically significant difference between the two groups in terms of the WBC (p>0.07).Conclusion: SAA levels have better discriminatory value than WBC or CRP in the assessment of acute appendicitis in children. Thus, this testappears to be of higher value than the current standards of care in the diagnosis of this condition.
AU  - Maral Kir, Hale
AU  - Ekingen, Gülşen
AU  - Akay, Mustafa Alper
AU  - ELEMEN, LEVENT
AU  - Vural, Çiğdem
DO  - 10.30934/kusbed.749382
PY  - 2021
JO  - Kocaeli Üniversitesi Sağlık Bilimleri Dergisi
VL  - 7
IS  - 1
SN  - 2149-8571
SP  - 27
EP  - 31
DB  - TRDizin
UR  - http://search/yayin/detay/425557
ER  -