Yıl: 2021 Cilt: 7 Sayı: 1 Sayfa Aralığı: 39 - 42 Metin Dili: İngilizce DOI: 10.30934/kusbed.757832 İndeks Tarihi: 21-06-2021

COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?

Öz:
Objective: Subclinical chronic inflammation plays an important role in the pathogenesis of type 2 diabetes mellitus (DM) and inflammation-relatedhemogram parameters have been proposed as an indicator of inflammation. In our study, we aimed to compare the hemogram parameters of normaloral glucose tolerance test (OGTT), prediabetes (preDM) and newly diagnosed type 2 DM patients.Methods: Medical data of the patients who underwent 75 gr OGTT in the endocrinology outpatient clinic of our institution between february 2019and december 2019 were obtained from the database and analyzed retrospectively. The test results were divided into 3 groups as normal OGTT,preDM and DM. Anthropometric measurements of patients, HbA1c and hemogram parameters were recorded.Results: A total of 496 cases (246 normal OGTT, 105 patients with preDM and 145 patients with DM) were included in the study. Fasting plasmaglucose (FPG) and HbA1c levels of men were higher than women (p<0.05). There was no significant difference between the three groups in terms ofinflammation-related hemogram parameters. But, there was a positive correlation between FPG and MPV to platelet ratio (MPR) in diabetic patients(r=0.173; p=0.037).Conclusion: Hemogram parameters associated with inflammation are easily calculated and cheap indices. However, they are not strong markers innew diagnosis, HbA1c ≤6.5% diabetic patients and prediabetic patients.
Anahtar Kelime:

İNFLAMASYONLA İLİŞKİLİ HEMOGRAM PARAMETRELERİ DİYABETES MELLİTUSUN BİR GÖSTERGESİ OLABİLİR Mİ?

Öz:
Amaç: Subklinik kronik inflamasyon tip 2 diabetes mellitus (DM) patogenezinde önemli bir rol oynar ve inflamasyonla ilişkili hemogram parametreleri inflamasyonun bir göstergesi olarak önerilmiştir. Çalışmamızda normal oral glukoz tolerans testi (OGTT), prediyabet (preDM) ve yeni tanı konmuş tip 2 DM hastalarının hemogram parametrelerini karşılaştırmayı amaçladık. Yöntem: Şubat 2019-Aralık 2019 tarihleri arasında kurumumuzun endokrinoloji polikliniğinde 75 gr OGTT uygulanan hastaların tıbbi verileri veri tabanından elde edilmiş ve geriye dönük olarak analiz edilmiştir. Test sonuçları normal OGTT, preDM ve DM olarak 3 gruba ayrıldı. Hastaların antropometrik ölçümleri, HbA1c ve hemogram parametreleri kaydedildi. Bulgular: Çalışmaya toplam 496 vaka (246 normal OGTT, 105 preDM'li hasta ve 145 DM'li hasta) dahil edildi. Erkeklerde açlık plazma glikozu (APG) ve HbA1c düzeyleri kadınlardan daha yüksekti (p<0,05). Üç grup arasında inflamasyonla ilişkili hemogram parametreleri açısından anlamlı fark yoktu. Ancak diyabetik hastalarda APG ile MPV/trombosit sayısı oranı (MPR) arasında pozitif korelasyon vardı (r= 0,173; p= 0,037). Sonuç: İnflamasyon ile ilişkili hemogram parametreleri kolayca hesaplanabilir ve ucuz indekslerdir. Bununla birlikte, yeni tanı, HbA1c ≤% 6,5 diyabetik hastalar ve prediyabetik hastalar için güçlü belirteçler değildir.
Anahtar Kelime:

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APA sözen m, çetinarslan b, canturk z, SELEK A, Gezer E, demirhan y, CETIN Y (2021). COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. , 39 - 42. 10.30934/kusbed.757832
Chicago sözen mehmet,çetinarslan berrin,canturk zeynep,SELEK ALEV,Gezer Emre,demirhan yeliz,CETIN YONCA COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. (2021): 39 - 42. 10.30934/kusbed.757832
MLA sözen mehmet,çetinarslan berrin,canturk zeynep,SELEK ALEV,Gezer Emre,demirhan yeliz,CETIN YONCA COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. , 2021, ss.39 - 42. 10.30934/kusbed.757832
AMA sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. . 2021; 39 - 42. 10.30934/kusbed.757832
Vancouver sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. . 2021; 39 - 42. 10.30934/kusbed.757832
IEEE sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y "COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?." , ss.39 - 42, 2021. 10.30934/kusbed.757832
ISNAD sözen, mehmet vd. "COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?". (2021), 39-42. https://doi.org/10.30934/kusbed.757832
APA sözen m, çetinarslan b, canturk z, SELEK A, Gezer E, demirhan y, CETIN Y (2021). COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi, 7(1), 39 - 42. 10.30934/kusbed.757832
Chicago sözen mehmet,çetinarslan berrin,canturk zeynep,SELEK ALEV,Gezer Emre,demirhan yeliz,CETIN YONCA COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 7, no.1 (2021): 39 - 42. 10.30934/kusbed.757832
MLA sözen mehmet,çetinarslan berrin,canturk zeynep,SELEK ALEV,Gezer Emre,demirhan yeliz,CETIN YONCA COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi, vol.7, no.1, 2021, ss.39 - 42. 10.30934/kusbed.757832
AMA sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi. 2021; 7(1): 39 - 42. 10.30934/kusbed.757832
Vancouver sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?. Kocaeli Üniversitesi Sağlık Bilimleri Dergisi. 2021; 7(1): 39 - 42. 10.30934/kusbed.757832
IEEE sözen m,çetinarslan b,canturk z,SELEK A,Gezer E,demirhan y,CETIN Y "COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?." Kocaeli Üniversitesi Sağlık Bilimleri Dergisi, 7, ss.39 - 42, 2021. 10.30934/kusbed.757832
ISNAD sözen, mehmet vd. "COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?". Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 7/1 (2021), 39-42. https://doi.org/10.30934/kusbed.757832