TY  - JOUR
TI  - COULD INFLAMMATION RELATED HEMOGRAM PARAMETERS BE AN INDICATOR OF DIABETES MELLITUS?
AB  - Objective: Subclinical chronic inflammation plays an important role in the pathogenesis of type 2 diabetes mellitus (DM) and inflammation-relatedhemogram parameters have been proposed as an indicator of inflammation. In our study, we aimed to compare the hemogram parameters of normaloral glucose tolerance test (OGTT), prediabetes (preDM) and newly diagnosed type 2 DM patients.Methods: Medical data of the patients who underwent 75 gr OGTT in the endocrinology outpatient clinic of our institution between february 2019and december 2019 were obtained from the database and analyzed retrospectively. The test results were divided into 3 groups as normal OGTT,preDM and DM. Anthropometric measurements of patients, HbA1c and hemogram parameters were recorded.Results: A total of 496 cases (246 normal OGTT, 105 patients with preDM and 145 patients with DM) were included in the study. Fasting plasmaglucose (FPG) and HbA1c levels of men were higher than women (p<0.05). There was no significant difference between the three groups in terms ofinflammation-related hemogram parameters. But, there was a positive correlation between FPG and MPV to platelet ratio (MPR) in diabetic patients(r=0.173; p=0.037).Conclusion: Hemogram parameters associated with inflammation are easily calculated and cheap indices. However, they are not strong markers innew diagnosis, HbA1c ≤6.5% diabetic patients and prediabetic patients.
AU  - demirhan, yeliz
AU  - CETIN, YONCA
AU  - sözen, mehmet
AU  - canturk, zeynep
AU  - SELEK, ALEV
AU  - çetinarslan, berrin
AU  - Gezer, Emre
DO  - 10.30934/kusbed.757832
PY  - 2021
JO  - Kocaeli Üniversitesi Sağlık Bilimleri Dergisi
VL  - 7
IS  - 1
SN  - 2149-8571
SP  - 39
EP  - 42
DB  - TRDizin
UR  - http://search/yayin/detay/425560
ER  -