TY  - JOUR
TI  - Investigation of C-reactive Protein and D-dimer Findings in Patients with COVID-19
AB  - Objective: The purpose of this study is to examine the levels ofC-reactive protein (CRP) and D-dimer by age and gender in thepandemic caused by the new coronavirus.Methods: Coronavirus disease-19 (COVID-19) diagnoses weremade according to the results of real-time polymerase chainreaction and lung computed tomography (n=70). In the study,CRP and coagulation were examined as indicators of inflammation,and D-dimer was examined as an indicator of fibrinolytic systemactivity. Patients’ age, gender, and CRP and D-dimer values wereanalyzed with Spearman’s rho correlation, whereas the gender factorwas analyzed with the Mann-Whitney U test.Results: Although D-dimer levels were high in women, there wasno statistical significance. A correlation was identified between CRPand gender, and the levels in male patients were higher (p=0.049).A positive correlation was found between the patients’ age and CRPand D-dimer findings.Conclusion: There are two main findings in this study. First, ageand gender are essential parameters in disease findings due to theCOVID-19 pandemic. Their importance overlaps with the findingthat inflammation is severe in elderly males and that the mortality ishigher than in younger individuals. Second, the CRP and D-dimertest results can be used as practical and reliable biomarkers forCOVID-19. We propose that if these two tests, which are alreadyused routinely, are interpreted with consideration of age and gender,they can be used more efficiently in early diagnosis and isolation.
AU  - yazar, hayrullah
AU  - Özdin, Mehmet
AU  - Kayacan, Yildirim
DO  - 10.14235/bas.galenos.2020.4884
PY  - 2021
JO  - Bezmiâlem Science
VL  - 9
IS  - 1
SN  - 2148-2373
SP  - 4
EP  - 8
DB  - TRDizin
UR  - http://search/yayin/detay/425697
ER  -