TY  - JOUR
TI  - Immunohistochemically Evaluation of PCNA and MMP-9 Expressions in Different Types of Canine Mammary Carcinomas
AB  - The aim of this study was to evaluate reveal whether there is a significant relationship between cell proliferation and invasion-metastasiscapacity in various mammary carcinomas subtypes observed in dogs immunohistochemically with PCNA and MMP-9 markers. Thematerial of this study consisted of tissue samples of mammary carcinomas taken from 6 Kangal and 4 Setter dogs with an average age of8.4 years brought to our department between 2012 and 2020. 4 of 10 mammary carcinoma cases were classified as intraductal papillarycarcinoma, 4 as carcinoma mixed, 1 as solid carcinoma and 1 as tubular carcinoma. We found the highest mean number of PCNA andMMP-9 positive cells in solid subtype. In conclusion, there may be a positive relationship between cell proliferation, invasion andmetastasis capacity under the solid subtype.
AU  - DAĞ, SERPİL
AU  - NUHOĞLU, HİLMİ
AU  - Karakurt, Emin
AU  - Oral, Hasan
AU  - BEYTUT, ENVER
AU  - KURU, Mushap
AU  - YILDIZ, Ayfer
DO  - 10.47027/duvetfd.794571
PY  - 2020
JO  - Dicle Üniversitesi Veteriner Fakültesi Dergisi
VL  - 13
IS  - 2
SN  - 1307-9972
SP  - 119
EP  - 124
DB  - TRDizin
UR  - http://search/yayin/detay/426077
ER  -