Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population

Celik, Mehmet; Ardahanlı, İsa

doi:10.5455/annalsmedres.2020.09.949

Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population

İsa ARDAHANLI, (Sağlık Bakanlığı)

Mehmet ÇELİK (Trakya Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Anabilim Dalı, Edirne, Türkiye)

Annals of Medical Research

1 1

Yıl: 2020 Cilt: 27 Sayı: 12 Sayfa Aralığı: 3117 - 3122 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.09.949 İndeks Tarihi: 27-06-2021

Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population

Öz:

Aim: Increased blood glucose concentration and cardiac autonomic nerve dysfunction are associated with an increased risk of malignant ventricular arrhythmia. Tp-e interval, Tp-e/QT, and Tp-e/QTc are novel parameters used to assess ventricular arrhythmogenicity. This study aimed to compare these parameters with the healthy control group in prediabetics. Materials and Methods: The ECGs of 58 prediabetic patients (29 male, 59.74 ±13.25 years) were examined and matched with the ECGs of 59 healthy controls (28 male, 61.75 ± 12.66 years) that were matched with gender, age and body mass index. From the 12-lead ECG Tp-e and QT intervals were measured and by Bazett's formula QTc was calculated. Tp-e/QT and Tp-e/QTc proportions were also determined. Results: In prediabetic patients, the mean Tp-e interval was significantly longer than the control group (79.07 ± 8.17 vs 72.03 ± 9.77 ms, respectively; p 0.001). Also in prediabetic, Tp-e/QT and Tp-e/QTc were significantly higher than the controls (respectively 0.21 ± 0.25 vs 0.19 ± 0.03 and 0.19 ± 0.02 vs 0.17 ± 0.02; p 0.001). Other ECG parameters were similar in both groups. HbA1c levels and glucose levels were positively correlated with Tp-e / QT and Tp-e / QTc. Conclusion: Prediabetes increases the risk of ventricular arrhythmogenesis by increasing the transmural dispersion of repolarization. The addition of Tp-e interval and TP-e / QT measurements to the routine ECG evaluation of prediabetic patients can be used to predict arrhythmia risk.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ardahanlı İ, Celik M (2020). Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. , 3117 - 3122. 10.5455/annalsmedres.2020.09.949
Chicago	Ardahanlı İsa,Celik Mehmet Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. (2020): 3117 - 3122. 10.5455/annalsmedres.2020.09.949
MLA	Ardahanlı İsa,Celik Mehmet Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. , 2020, ss.3117 - 3122. 10.5455/annalsmedres.2020.09.949
AMA	Ardahanlı İ,Celik M Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. . 2020; 3117 - 3122. 10.5455/annalsmedres.2020.09.949
Vancouver	Ardahanlı İ,Celik M Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. . 2020; 3117 - 3122. 10.5455/annalsmedres.2020.09.949
IEEE	Ardahanlı İ,Celik M "Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population." , ss.3117 - 3122, 2020. 10.5455/annalsmedres.2020.09.949
ISNAD	Ardahanlı, İsa - Celik, Mehmet. "Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population". (2020), 3117-3122. https://doi.org/10.5455/annalsmedres.2020.09.949

APA	Ardahanlı İ, Celik M (2020). Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. Annals of Medical Research, 27(12), 3117 - 3122. 10.5455/annalsmedres.2020.09.949
Chicago	Ardahanlı İsa,Celik Mehmet Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. Annals of Medical Research 27, no.12 (2020): 3117 - 3122. 10.5455/annalsmedres.2020.09.949
MLA	Ardahanlı İsa,Celik Mehmet Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. Annals of Medical Research, vol.27, no.12, 2020, ss.3117 - 3122. 10.5455/annalsmedres.2020.09.949
AMA	Ardahanlı İ,Celik M Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. Annals of Medical Research. 2020; 27(12): 3117 - 3122. 10.5455/annalsmedres.2020.09.949
Vancouver	Ardahanlı İ,Celik M Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population. Annals of Medical Research. 2020; 27(12): 3117 - 3122. 10.5455/annalsmedres.2020.09.949
IEEE	Ardahanlı İ,Celik M "Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population." Annals of Medical Research, 27, ss.3117 - 3122, 2020. 10.5455/annalsmedres.2020.09.949
ISNAD	Ardahanlı, İsa - Celik, Mehmet. "Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population". Annals of Medical Research 27/12 (2020), 3117-3122. https://doi.org/10.5455/annalsmedres.2020.09.949