Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study

KOK, AHMET NEZIH; çağlar, özgür; atalay, canan; Malçok, Ümit Ali; Aydin, Mehmet Dumlu; ERDOĞAN, AYSEL; AYDIN, Muhammed Enes; GÜNDOĞDU, BETÜL

doi:10.5455/annalsmedres.2020.10.1074

Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study

Muhammed Enes AYDIN, (Atatürk Üniversitesi, Tıp Fakültesi, Anesteziyoloji Anabilim Dalı, Erzurum, Türkiye)

Ümit Ali MALÇOK, (Çanakkale Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Çanakkale, Türkiye)

Aysel ERDOĞAN, (Erzincan Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Erzincan, Türkiye)

Özgür ÇAĞLAR, (Atatürk Üniversitesi, Tıp Fakültesi, Çocuk Cerrahisi Anabilim Dalı, Erzurum, Türkiye)

Mehmet AYDIN, (Atatürk Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Erzurum, Türkiye)

Canan ATALAY, (Çanakkale Üniversitesi, Tıp Fakültesi, Nöroşirürji Anabilim Dalı, Çanakkale, Türkiye)

Betül GÜNDOĞDU, (Atatürk Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Erzurum, Türkiye)

Ahmet Nezih KÖK (Atatürk Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Erzurum, Türkiye)

Annals of Medical Research

6 0

Yıl: 2021 Cilt: 28 Sayı: 1 Sayfa Aralığı: 95 - 100 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.10.1074 İndeks Tarihi: 28-06-2021

Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study

Öz:

Aim: Although acute respiratory arrest is the most dangerous complication of subarachnoid hemorrhage; if there is any association between hypoglossal nerve-tongue palsy induced acute mechanical upper airway obstruction has not been extensively described so far. Our aim is to evaluate if there is a relationship between hypoglossal ischemia-tongue paralysis and upper airway obstruction during subarachnoid hemorrhage.Materials and Methods: Formerly studied 23 rabbits’s documents chosen from our SAH experiments. A control group (Group A) include 5 normal animals, Sham group (Group B) include 5 animals which saline was administered, and a study group (Group C) include 13 animals (7 survive-C1 / 6 dead-C2) which were injected with homologous blood into the cisterna magna. Blood pressure values and and electrocardiograhic changes were recorded per days of all animals before, during and after surgery during two weeks and all animals decapitated under general anesthesia. Hypoglossal nerves, tongue muscles and upper arways were evaluated. Numbers of degenerated axons/neurons density of hypoglossal nerves-atrophic tongue muscles and airway obstruction scores (AOS) of all animals were determined and analysed statistically with ANOVA. AOS was classified according to tongual sliding down distances to larynx numbered between 1-7 mm to scored with 1-7.Results: Important neurodegeneration was noticed in axons of the hypoglosssal nerves and tongue muscle denervation injury was in more severe in AOS observed animals. The hypoglossal nerves, degenerated axon density (n/mm2), numbers of atrophic muscles (n/mm3) and AOS was: 4±2, 1±1, 1±1 in A; 7±3, 2±1, 2±1 in B and 98±11, 23±5, 5±2 in C1 groups. P values between the axonal degeneration of hypoglossal nerves/muscles and AOS was p<0.005 for C2/C1; p<0.0005 for C2/A and p<0.0001 C2/B. Conclusion: Hypoglossal ischemia induced tongual muscle palsy related respiratory arrest should be remembered in neurocritical cases. Maintaining normal respiratory functions is only possible with airway tone, which is possible with an intact hypoglossal nerve.

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1. Iaconetta G, Solari D, Villa A, et al. The Hypoglossal Nerve: Anatomical Study of Its Entire Course. World Neurosurgery 2018;109:e486-e92.
2. Muellbacher W, Artner C, Mamoli B. Motor evoked potentials in unilateral lingual paralysis after monohemispheric ischaemia. J Neurol Neurosurg Psychiatry 1998;65:755-61.
3. Anjaneyulu A, Mohandas S. Hypoglossal nerve palsy in association with non aneurismal subarachnoid haemorrhage during pregnancy. Neurol India 1995;43:60.
4. Kacker A, Komisar A, Kakani RS, et al. Tongue paralysis following head trauma. J Laryngol Oto 1995;109:770- 1.
5. Dziedzic TA, Kunert P, Marchel A. Hemihypoglossal- Facial Nerve Anastomosis for Facial Nerve Reanimation: Case Series and Technical Note. World Neurosurg 2018;118:e460-e7.
6. Ibarra V, Jaureguiberry A, Moretta G, et al. Idiopathic and unilateral hypoglossal nerve palsy. Medicina (B Aires) 2015;75:173-4.
7. Chi MS, Ng SH, Chan LY. Asymmetric Acute Motor Axonal Neuropathy With Unilateral Tongue Swelling Mimicking Stroke. Neurologist 2016;21:106-8.
8. Tubbs RS, Vahedi P, Loukas M, et al. Hubert von Luschka (1820-1875): his life, discoveries, and contributions to our understanding of the nervous system. J Neurosurg 2011;114:268-72.
9. Ateş S, Karakurum E, Dursun N. Origin, course and distribution of the hypoglossal nerve in the New Zealand rabbit (Oryctolagus cuniculus L). Anat Histol Embryol 2011;40:360-4.
10. Frizell M, Sjöstrand J. The axonal transport of slowly migrating (3H)leucine labelled proteins and the regeneration rate in regenerating hypoglossal and vagus nerves of the rabbit. Brain Res 1974;81:267-83.
11. Fernando DA, Lord RS, Ozmen J. The blood supply of the hypoglossal nerve and its relevance to carotid endarterectomy. Cardiovasc Surg 1999;7:287-91.
12. Uemura-Sumi M, Itoh M, Mizuno N. The distribution of hypoglossal motoneurons in the dog, rabbit and rat. Anat Embryol (Berl). 1988;177:389-94.
13. Ouahchi Y, Marie JP, Verin E. Effect of lingual paralysis on swallowing and breathing coordination in rats. Respir Physiol Neurobiol 2012;181:95-8.
14. Homma I, Iwase M, Kanamaru A, et al. Pre-inspiratory burst in the caudal medulla of rabbits. Neurosci Lett 1990;113:270-4.
15. Lund JP, Dellow PG. Rhythmical masticatory activity of hypoglossal motoneurons responding to an oral stimulus. Exp Neurol 1973;40:243-6.
16. Benderro GF, Gamble J, Schiefer MA, et al. Hypoglossal nerve stimulation in a pre-clinical anesthetized rabbit model relevant to OSA. Respir Physiol Neurobiol 2018;250:31-8.
17. Bu Bshait M, Alyami H, Al-Osail E, et al. Ipsilateral hypoglossal nerve palsy following left hemithyroidectomy: Case report and review of literature. Int J Surg Case Rep 2018;51:5-7.
18. Batchelor TT, Krol GS, DeAngelis LM. Neuroimaging abnormalities with hypoglossal nerve palsies. J Neuroimaging 1996;6:240-2.
19. Nestola DF, Lombardi M, Brucoli M, et al. Isolated hypoglossal nerve palsy mimicking a base of tongue tumor. J Craniofac Surg 2017;28:e78-e80.
20. Nakamura S, Hayashi K, Sakamaki H, et al. Propofol depresses the activity of hypoglossal nerve more than that of phrenic nerve in rabbits. Masui 2003;52:135- 42.
21. Hosemann W, Wigand ME, Herrlinger P, et al. Surgical reneurotization of the tongue after unilateral paralysis of the hypoglossal nerve. Eur Arch Otorhinolaryngol 1990;248:95-8.
22. Oushy S, Graffeo CS, Perry A, et al. Colletsicard syndrome attributable to extramedullary plasmacytoma of the jugular foramen. World Neurosurg 2018;110:386-90.
23. Stepień A, Durka-Kesy M, Warczyńska A. [Compression neuropathy of cranial nerves in the course of Takayasu arteritis]. Neurol Neurochir Pol 2007;41:557-61.
24. Ishikawa M, Kusaka G, Takashima K, et al. Clipping of a vertebral artery aneurysm behind the hypoglossal nerve under the monitoring of lower cranial nerves. Clin Neurol Neurosurg 2010;112:450-3.
25. Lim MS, Kaar GF. Spontaneous Fractures in the Setting of Extensive Craniocervical Pneumatization: Case Report and Literature Review. World Neurosurg 2019;123:165-7.
26. Plitt A, El Ahmadieh TY, Bindal S, et al. Hypoglossal schwannoma of neck: case report and review of literature. World Neurosurg 2018;110:240-3.
27. Sawamura A, Kamiyama H, Kobayashi N, et al. [Ruptured persistent primitive hypoglossal artery aneurysm: case report]. No Shinkei Geka 1999;27:633- 8.
28. Saunders WH, Hodgson SE. Bilateral hypoglossal nerve paralysis after irradiation therapy. Ann Otol Rhinol Laryngol 1979;88:515-7.
29. Keane JR. Twelfth-nerve palsy. Analysis of 100 cases. Arch Neurol. 1996;53:561-6.
30. Gassie K, Grewal S, Chen SG. Atlantooccipital synovial cyst with isolated hypoglossal nerve palsy: case report of nonfusion surgical approach and review of literature. World Neurosurg 2019;126:434-8.
31. Kojima A, Saga I, Ishikawa M. Intraoperative hypoglossal nerve mapping during carotid endarterectomy: technical note. World Neurosurg 2018;113:249-53.
32. Bellemare F, Pecchiari M, Bandini M, et al. Reversibility of airflow obstruction by hypoglossus nerve stimulation in anesthetized rabbits. Am J Respir Crit Care Med 2005;172:606-12.

APA	AYDIN M, Malçok Ü, ERDOĞAN A, çağlar ö, Aydin M, atalay c, GÜNDOĞDU B, KOK A (2021). Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. , 95 - 100. 10.5455/annalsmedres.2020.10.1074
Chicago	AYDIN Muhammed Enes,Malçok Ümit Ali,ERDOĞAN AYSEL,çağlar özgür,Aydin Mehmet Dumlu,atalay canan,GÜNDOĞDU BETÜL,KOK AHMET NEZIH Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. (2021): 95 - 100. 10.5455/annalsmedres.2020.10.1074
MLA	AYDIN Muhammed Enes,Malçok Ümit Ali,ERDOĞAN AYSEL,çağlar özgür,Aydin Mehmet Dumlu,atalay canan,GÜNDOĞDU BETÜL,KOK AHMET NEZIH Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. , 2021, ss.95 - 100. 10.5455/annalsmedres.2020.10.1074
AMA	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. . 2021; 95 - 100. 10.5455/annalsmedres.2020.10.1074
Vancouver	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. . 2021; 95 - 100. 10.5455/annalsmedres.2020.10.1074
IEEE	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A "Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study." , ss.95 - 100, 2021. 10.5455/annalsmedres.2020.10.1074
ISNAD	AYDIN, Muhammed Enes vd. "Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study". (2021), 95-100. https://doi.org/10.5455/annalsmedres.2020.10.1074

APA	AYDIN M, Malçok Ü, ERDOĞAN A, çağlar ö, Aydin M, atalay c, GÜNDOĞDU B, KOK A (2021). Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. Annals of Medical Research, 28(1), 95 - 100. 10.5455/annalsmedres.2020.10.1074
Chicago	AYDIN Muhammed Enes,Malçok Ümit Ali,ERDOĞAN AYSEL,çağlar özgür,Aydin Mehmet Dumlu,atalay canan,GÜNDOĞDU BETÜL,KOK AHMET NEZIH Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. Annals of Medical Research 28, no.1 (2021): 95 - 100. 10.5455/annalsmedres.2020.10.1074
MLA	AYDIN Muhammed Enes,Malçok Ümit Ali,ERDOĞAN AYSEL,çağlar özgür,Aydin Mehmet Dumlu,atalay canan,GÜNDOĞDU BETÜL,KOK AHMET NEZIH Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. Annals of Medical Research, vol.28, no.1, 2021, ss.95 - 100. 10.5455/annalsmedres.2020.10.1074
AMA	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. Annals of Medical Research. 2021; 28(1): 95 - 100. 10.5455/annalsmedres.2020.10.1074
Vancouver	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study. Annals of Medical Research. 2021; 28(1): 95 - 100. 10.5455/annalsmedres.2020.10.1074
IEEE	AYDIN M,Malçok Ü,ERDOĞAN A,çağlar ö,Aydin M,atalay c,GÜNDOĞDU B,KOK A "Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study." Annals of Medical Research, 28, ss.95 - 100, 2021. 10.5455/annalsmedres.2020.10.1074
ISNAD	AYDIN, Muhammed Enes vd. "Unpredicted respiratory arrest following hypoglossal nerve palsy during subarachnoid hemorrhage: Experimental study". Annals of Medical Research 28/1 (2021), 95-100. https://doi.org/10.5455/annalsmedres.2020.10.1074