Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

Balusamy, Brabu; Uyar, Tamer; senthamizhan, anitha

doi:10.15671/hjbc.789186

Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

Brabu BALUSAMY, (Department of Fiber Science & Apparel Design, College of Human Ecology, Cornell University, Ithaca, USA.)

Anitha SENTHAMİZHAN, (Department of Fiber Science & Apparel Design, College of Human Ecology, Cornell University, Ithaca, USA.)

Tamer UYAR (Department of Fiber Science & Apparel Design, College of Human Ecology, Cornell University, Ithaca, USA.)

Hacettepe Journal of Biology and Chemistry

17 0

Yıl: 2020 Cilt: 48 Sayı: 5 Sayfa Aralığı: 459 - 481 Metin Dili: İngilizce DOI: 10.15671/hjbc.789186 İndeks Tarihi: 29-06-2021

Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

Öz:

Electrospinning has received tremendous attention in the fabrication of nanofibrous scaffolds over recent years andemployed in different biomedical applications because of their biomimetic nature. Especially, the electrospunnanofibers exhibit several beneficial features including natural extracellular matrix (ECM), interconnected pores, largesurface area, ease of functionalization and mechanical performance that holds huge importance in influencing the celladhesion, differentiation and proliferation behaviour. To date, acknowledging the wide range of beneficial features, theelectrospun nanofibers have been used in wound dressing and tissue engineering applications. This review summarizesvarious efforts have been made in these areas with several representative examples indicating use of various materials andapproaches. Further the concerns for future direction regard to clinical phase transfer has been discussed.

Anahtar Kelime:

Yara Örtüsü ve Doku Mühendisliği Uygulamaları için Elektro-eğirme ile Üretilen Nanolifler

Öz:

Elektro-eğirme yöntemi ile üretilen nanolifler, son yıllarda nanofibröz yapı iskelelerinin geliştirilmesinde büyük ilgi gördü ve biyomimetik yapıları nedeniyle farklı biyomedikal uygulamalarda kullanıldı. Özellikle, elektro-eğirme yöntemi ile üretilen nanolifler doğal hücre dışı matris (ECM), birbirine bağlı gözenekler, geniş yüzey alanı, işlevselleştirme kolaylığı ve hücre adezyonunu, farklılaşmasını ve proliferasyon davranışını etkilemede büyük önem taşıyan mekanik performans dahil olmak üzere birçok faydalı özellik sergiler. Bugüne kadar, çok çeşitli yararlı özellikleri kabul eden bu nanolifler, yara örtüsü ve doku mühendisliği uygulamalarında kullanılmıştır. Bu derlemede, çeşitli malzemelerin ve yaklaşımların kullanımını gösteren birkaç temsili örneklerle bu alanlarda çeşitli çabaların yapıldığını özetlemektedir. Ayrıca, klinik faz transferine ilişkin gelecekteki yön endişeleri tartışılmıştır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Balusamy B, senthamizhan a, Uyar T (2020). Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. , 459 - 481. 10.15671/hjbc.789186
Chicago	Balusamy Brabu,senthamizhan anitha,Uyar Tamer Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. (2020): 459 - 481. 10.15671/hjbc.789186
MLA	Balusamy Brabu,senthamizhan anitha,Uyar Tamer Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. , 2020, ss.459 - 481. 10.15671/hjbc.789186
AMA	Balusamy B,senthamizhan a,Uyar T Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. . 2020; 459 - 481. 10.15671/hjbc.789186
Vancouver	Balusamy B,senthamizhan a,Uyar T Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. . 2020; 459 - 481. 10.15671/hjbc.789186
IEEE	Balusamy B,senthamizhan a,Uyar T "Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications." , ss.459 - 481, 2020. 10.15671/hjbc.789186
ISNAD	Balusamy, Brabu vd. "Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications". (2020), 459-481. https://doi.org/10.15671/hjbc.789186

APA	Balusamy B, senthamizhan a, Uyar T (2020). Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry, 48(5), 459 - 481. 10.15671/hjbc.789186
Chicago	Balusamy Brabu,senthamizhan anitha,Uyar Tamer Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry 48, no.5 (2020): 459 - 481. 10.15671/hjbc.789186
MLA	Balusamy Brabu,senthamizhan anitha,Uyar Tamer Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry, vol.48, no.5, 2020, ss.459 - 481. 10.15671/hjbc.789186
AMA	Balusamy B,senthamizhan a,Uyar T Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry. 2020; 48(5): 459 - 481. 10.15671/hjbc.789186
Vancouver	Balusamy B,senthamizhan a,Uyar T Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry. 2020; 48(5): 459 - 481. 10.15671/hjbc.789186
IEEE	Balusamy B,senthamizhan a,Uyar T "Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications." Hacettepe Journal of Biology and Chemistry, 48, ss.459 - 481, 2020. 10.15671/hjbc.789186
ISNAD	Balusamy, Brabu vd. "Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications". Hacettepe Journal of Biology and Chemistry 48/5 (2020), 459-481. https://doi.org/10.15671/hjbc.789186