TY  - JOUR
TI  - Flow cytometric evaluation and outcomes of pediatric acute leukemia patients
AB  - Purpose: In this study, the outcomes and flow cytometryresults of our pediatric acute leukemia patients and theirrelationship with the prognosis and other clinicalconditions were investigated.Materials and Methods: A total of 93 patients, 69 acutelymphoblastic leukemia (ALL) and 24 acute myeloidleukemia (AML) diagnosed at our clinic between January2008 and November 2013, were included.Results: 5-year overall survival (OS) was 66% in ALLpatients and 80% in AML patients. When leukemiapatients were classified flow cytometrically according totheir cell surface antigens (CD); 5-year OS was 58% inCD2(+) patients and 77% in CD2(-) patients. Five-yearOS was 82% in patients with CD10(+) and 61% in patientswith CD10(-). ALL patients were divided into two groupsas ALL with positive T cell markers and ALL with positiveB cell markers in the foreground and evaluatedaccordingly, and the OS of ALL patients with positive Tcell markers in the foreground was lower than ALLpatients with positive B cell markers in the 5 year (59% and75%, respectively).Conclusion: In the flow cytometric evaluation of ourpatients with leukemia, patients with CD10(+) had a better5-year OS and patients with CD2(+) had a lower 5-yearOS. The results of patients with positive B cell markerswere better in ALL patients, and the results of patientswith positive lymphoid markers were better in AMLpatients.
AU  - Ozkan, Ayse
AU  - BAYRAM, İBRAHİM
AU  - Tanyeli, Atila
AU  - CAVLAK, Burcu Genç
AU  - Küpeli, Serhan
AU  - Sezgin, Gülay
DO  - 10.17826/cumj.790247
PY  - 2021
JO  - Cukurova Medical Journal
VL  - 46
IS  - 1
SN  - 2602-3032
SP  - 149
EP  - 159
DB  - TRDizin
UR  - http://search/yayin/detay/429355
ER  -