TY  - JOUR
TI  - Evaluation of clinical and pathological features of mixed endometrial carcinoma in a tertiary medical center
AB  - Purpose: The aim of this study was to evaluate the clinicaland pathological characteristics of mixed endometrialcarcinoma (MEC).Materials and Methods: The clinical and pathologicalrecords of the 29 MEC patients, who were operated onand regularly followed up in the clinic between January2000 and December 2019, were reviewed. Clinicpathologic features and survival in the MEC group (n=29)were compared to pure serous (n=42) and pure clear celladenocarcinomas (n=13). Clinical features, operationcharacteristics, pathological findings, myometrial invasiondegree (MI), lymph node involvement (LNI),lymphovascular space invasion (LVSI), adjuvant therapies,and follow-up data of the patients and their effects onsurvival were investigated.Results: Eighteen of the cases had endometrioid + serous,7 had endometrioid + clear, 3 had endometrioid + serous,and 1 had clear + serous histopathology. Laparoscopicsurgery was performed in 8 of the cases (27.6%) in themixed group. Stage, the rate of LVSI, LNI, MI ≥50%, andomental metastasis were similar among the groups. Therewere no significant differences in the rates of receivingadjuvant therapy among the groups. Overall survive (OS)was similar among the groups.Conclusion: MECs are tumors that can be difficult todiagnose and manage. There was no difference betweenMEC and pure serous carcinoma (SC) and pure clear cellcarcinoma (CC) in terms of clinicopathological featuresand prognosis. In addition to histopathological features,revealing and evaluating their molecular properties willhelp us to better understand this group of tumors.
AU  - akçabay, çiğdem
AU  - Sucu, Mete
AU  - vardar, Mehmet
AU  - güzel, ahmet barış
AU  - Khatib, Ghanim
AU  - Kucukgoz Gulec, Umran
AU  - GEÇKİL, Ömer Faruk
DO  - 10.17826/cumj.866381
PY  - 2021
JO  - Cukurova Medical Journal
VL  - 46
IS  - 1
SN  - 2602-3032
SP  - 395
EP  - 400
DB  - TRDizin
UR  - http://search/yayin/detay/429783
ER  -