TY  - JOUR
TI  - Evaluating Effects of Black Carrot Extract on Testicular Carboxylesterase Activity and Oxidative Stress Parameters in Rats Exposed to Bisphenol A
AB  - We aimed to evaluate the effects of black carrot extract on testicular carboxylesterase (Ces)activity, malondialdehyde (MDA), glutathione S-transferases (GST) and reduced glutathione(GSH) in male rats exposed to bisphenol A (BPA). Adult Wistar albino male rats were dividedinto 4 groups as follows (n = 7/group): control, BPA, black carrot and BPA+Black carrot.Testicular Ces, MDA, GST and reduced GSH were analyzed by using a spectrophotometersystem. Testicular Ces activity was significantly lower only in the BPA group than the controlgroup (p < 0.001). Testicular MDA concentrations were higher only in the BPA group comparedwith the control group (p < 0.001). Reduced GSH level was higher in the black carrot andBPA+Black carrot groups than the control group (p < 0.05). GST activity was lower in the BPA group in comparison to the control group (p < 0.05). In the black carrot and BPA+Black carrotgroups, the GST activities were higher than the control group (p < 0.001). Our results showedBPA suppresses testicular detoxification activity and increases lipid peroxidation in rats. Weobserved that black carrot extract has a beneficial effect on the toxic and oxidative stress-relatedparameters caused by BPA exposure.
AU  - Yoloğlu, Ertan
AU  - şahin, yunus
AU  - Özkaya, Ahmet
AU  - UÇKUN, MIRAÇ
AU  - Bulmus, Ozgur
AU  - Şahin, Zafer
DO  - 10.37094/adyujsci.782874
PY  - 2021
JO  - Adıyaman Üniversitesi Fen Bilimleri Dergisi
VL  - 11
IS  - 1
SN  - 2147-1630
SP  - 73
EP  - 86
DB  - TRDizin
UR  - http://search/yayin/detay/436424
ER  -