Plasma d-dimer levels increase with the severity of community acquired pneumonia

PİRMİT, Serpil; GÜNEYSEL, Özlem; KARAKURT, SAİT

Plasma d-dimer levels increase with the severity of community acquired pneumonia

Özlem GÜNEYSEL, (Marmara Üniversitesi, Tıp Fakültesi, İlk ve Acil Yardım Anabilim Dalı, İstanbul, Türkiye)

Serpil PİRMİT, (Marmara Üniversitesi, Tıp Fakültesi, İlk ve Acil Yardım Anabilim Dalı, İstanbul, Türkiye)

Sait KARAKURT (Marmara Üniversitesi, Tıp Fakültesi, Göğüs Hastalıkları ve Yoğun Bakım Anabilim Dalı, İstanbul, Türkiye)

Tüberküloz ve Toraks

1 0

Yıl: 2004 Cilt: 52 Sayı: 4 Sayfa Aralığı: 341 - 347 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Plasma d-dimer levels increase with the severity of community acquired pneumonia

Öz:

Bu çalışmanın amacı, plazma D-dimer (D-d) düzeyi ile toplum kökenli pnömoni (TKP) arasındaki ilişkiyi araştırmaktır. Bu çalışma, prospeküf kontrollü olarak yapılmıştır. ATS 2001 TKP Rehberi kullanılarak hastalar iki gruba [hafif (n= 37) ve ağır pnömoni (n= 14)1 ayrıldı. Kontrol grubu da dahil edilerek tüm gruplarda plazma D-d düzeyi ELISA yöntemi ile araştırıldı. Plazma D-d düzeyleri ağır pnömoni grubunda 2438 ± 2158 ng/mL, hafif pnömoni grubunda 912.6 ± 512.6 ng/mL ve kontrol grubunda 387 ± 99.56 ng/mL olarak bulundu. Kontrol grubuyla karşılaştırıldığında hafif (p< 0.05) ve ağır (p< 0.001) pnömoni gruplarında plazma D-d düzeylerinin anlamlı arttığı gözlendi. Ayrıca hasta grupları kendi aralarında karşılaştırıldığında, hastalığın şiddetiyle orantılı olarak plazma D-d düzeylerinin de arttığı bulunmuştur. TKP'li hastalarda plazma D-d düzeyleri yükselmektedir. D-d düzeyleri hastalığın şiddetiyle orantılı olarak artmaktadır.

Anahtar Kelime: Hastalık ciddiyet indeksi Plazma Toplum kökenli enfeksiyonlar

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Plazma d-dimer düzeyi toplum kökenli pnömoninin ağırlığıyla orantılı olarak artmaktadır.

Öz:

The aim of this study is to investigate the relationship of the plasma D-Dimer (D-d) level and the severity of the pneumonia in patients who have not any disease that may increase the D-d level, but pneumonia. This is prospective controlled study. Using the ATS 2001 Community Acquired Pneumonia (CAP) Guideline we divided the patients into two groups [severe (n= 14) and non-severe (n= 37) CAP] and looked for any significant difference in D-d tevels with ELISA method among the patients groups and control group. Plasma D-d levels were 2438 ± 2158 ng/mL in severe CAP group, 912.6 ± 512.6 ng/mL in non-severe CAP group and 387 ± 99.56 ng/mL in the control group. Patients with non-severe CAP and those with severe CAP group both showed an increase in plasma levels of D-d compared to control group (p< 0.05, p< 0.001, respectively). We also found that the severe CAP group had increased in plasma levels of D-d compared to the non-severe CAP group (p< 0.001). Plasma D-d level increases significantly in patients with CAP compared to control group. Plasma D-d levels increases significantly with the severity of the CAP.

Anahtar Kelime: Severity of Illness Index Plasma Community-Acquired Infections

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	GÜNEYSEL Ö, PİRMİT S, KARAKURT S (2004). Plasma d-dimer levels increase with the severity of community acquired pneumonia. , 341 - 347.
Chicago	GÜNEYSEL Özlem,PİRMİT Serpil,KARAKURT SAİT Plasma d-dimer levels increase with the severity of community acquired pneumonia. (2004): 341 - 347.
MLA	GÜNEYSEL Özlem,PİRMİT Serpil,KARAKURT SAİT Plasma d-dimer levels increase with the severity of community acquired pneumonia. , 2004, ss.341 - 347.
AMA	GÜNEYSEL Ö,PİRMİT S,KARAKURT S Plasma d-dimer levels increase with the severity of community acquired pneumonia. . 2004; 341 - 347.
Vancouver	GÜNEYSEL Ö,PİRMİT S,KARAKURT S Plasma d-dimer levels increase with the severity of community acquired pneumonia. . 2004; 341 - 347.
IEEE	GÜNEYSEL Ö,PİRMİT S,KARAKURT S "Plasma d-dimer levels increase with the severity of community acquired pneumonia." , ss.341 - 347, 2004.
ISNAD	GÜNEYSEL, Özlem vd. "Plasma d-dimer levels increase with the severity of community acquired pneumonia". (2004), 341-347.

APA	GÜNEYSEL Ö, PİRMİT S, KARAKURT S (2004). Plasma d-dimer levels increase with the severity of community acquired pneumonia. Tüberküloz ve Toraks, 52(4), 341 - 347.
Chicago	GÜNEYSEL Özlem,PİRMİT Serpil,KARAKURT SAİT Plasma d-dimer levels increase with the severity of community acquired pneumonia. Tüberküloz ve Toraks 52, no.4 (2004): 341 - 347.
MLA	GÜNEYSEL Özlem,PİRMİT Serpil,KARAKURT SAİT Plasma d-dimer levels increase with the severity of community acquired pneumonia. Tüberküloz ve Toraks, vol.52, no.4, 2004, ss.341 - 347.
AMA	GÜNEYSEL Ö,PİRMİT S,KARAKURT S Plasma d-dimer levels increase with the severity of community acquired pneumonia. Tüberküloz ve Toraks. 2004; 52(4): 341 - 347.
Vancouver	GÜNEYSEL Ö,PİRMİT S,KARAKURT S Plasma d-dimer levels increase with the severity of community acquired pneumonia. Tüberküloz ve Toraks. 2004; 52(4): 341 - 347.
IEEE	GÜNEYSEL Ö,PİRMİT S,KARAKURT S "Plasma d-dimer levels increase with the severity of community acquired pneumonia." Tüberküloz ve Toraks, 52, ss.341 - 347, 2004.
ISNAD	GÜNEYSEL, Özlem vd. "Plasma d-dimer levels increase with the severity of community acquired pneumonia". Tüberküloz ve Toraks 52/4 (2004), 341-347.