Yıl: 2020 Cilt: 31 Sayı: 4 Sayfa Aralığı: 239 - 243 Metin Dili: Türkçe DOI: 10.5080/u25205 İndeks Tarihi: 24-09-2021

Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları

Öz:
Amaç: Kannabis kullanımının retina sinir lifi tabakası (RSLT) vemaküler ganglion hücre-iç pleksiform tabaka (MGH-İPT) üzerineolan yapısal etkilerinin optik koherens tomografi ile değerlendirilmesiamaçlanmıştır.Yöntem: Bu prospektif, karşılaştırmalı çalışmaya Muş Devlet HastanesiPsikiyatri Polikliniği’ne başvuran ve kannabis kullanımı mevcut olan26 kişi ile bu kişilerle yaş ve cinsiyet açısından uyumlu 27 sağlıklıgönüllü dâhil edilmiştir. Her iki gruba optik koherens tomografi (OKT)çekimi uygulanmıştır. OKT cihazı tarafından otomatik olarak ölçülenRSLT ve MGH-İPT kalınlıkları kaydedilerek her iki grup arasındakarşılaştırılmıştır.Bulgular: Her iki grup arasında sosyodemografik veriler açısındananlamlı bir fark saptanmadı. Ortalama retina sinir lifi kalınlığı ilesüperior, nazal ve inferior kadranlarda iki grup arasındaki fark istatistikselolarak anlamlı değilken temporal kadranda istatistiksel olarak anlamlıfark saptanmıştır (p=0,022). Maküler ganglion hücre-iç pleksiformtabaka kalınlıklarının analizinde ise her iki grup arasında ortalama,inferotemporal, inferior, inferonasal ve süperonazal kadranlardaanlamlı bir fark saptanmazken süperior ve süperotemporal kadranlardaistatistiksel olarak anlamlı incelme saptanmıştır (p=0,006; p=0,027).Sonuç: Bu bulgular kannabis kullanımının retina tabakaları üzerindeincelmeye yol açtığını desteklemektedir. Beynin kolayca izlenebilirparçası olması bakımından retina sinir lifi ve ganglion hücre tabakasınınOKT ile değerlendirilmesi kannabis kullananlarda toksik ve dejeneratifetkinin takibi açısından önemli olabilir.
Anahtar Kelime:

Optical Coherence Tomography Findings in Cannabis Users

Öz:
Objective: In this study, we aimed to evaluate the effects of cannabis use on the retinal nerve fiber layer (RNFL) and the macular ganglion cell – inner plexiform layer GCL-IPL using optical coherence tomography (OCT). Method: This prospective, comparative study included 26 cannabis users who were evaluated at the Psychiatry Outpatient Unit of Muş State Hospital and 27 age and gender matched healthy controls. OCT was performed on both groups. The RNFL and GCL - IPL thicknesses, measured automatically by OCT, were recorded and compared between the groups. Results: The sociodemographic parameters of the two groups did not differ. The mean retinal nerve fiber thickness and thickness at the superior, nasal, inferior quadrants were not significantly different; but there was a significant difference at the temporal quadrant (p=0,022). In the analysis of macular ganglion cell – inner plexiform layer, the mean values as well as the infetotemporal, inferior, inferonasal and superonasal quadrants did not show significant differences. But there was a statistically significant decrease in the superior and superotemporal quadrants (p=0,006, p=0,027). Conclusion: These findings suggest that cannabis use leads to the thinning on retinal layers. As it is an easily observable part of the brain, evaluating retinal nerve fiber and ganglion cell layer with OCT may be important for monitoring toxic and degenerative effects in cannabis users.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA dayi a, dayi o, kurt e, Yorguner N (2020). Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. , 239 - 243. 10.5080/u25205
Chicago dayi ali,dayi ozlem,kurt emel,Yorguner Nese Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. (2020): 239 - 243. 10.5080/u25205
MLA dayi ali,dayi ozlem,kurt emel,Yorguner Nese Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. , 2020, ss.239 - 243. 10.5080/u25205
AMA dayi a,dayi o,kurt e,Yorguner N Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. . 2020; 239 - 243. 10.5080/u25205
Vancouver dayi a,dayi o,kurt e,Yorguner N Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. . 2020; 239 - 243. 10.5080/u25205
IEEE dayi a,dayi o,kurt e,Yorguner N "Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları." , ss.239 - 243, 2020. 10.5080/u25205
ISNAD dayi, ali vd. "Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları". (2020), 239-243. https://doi.org/10.5080/u25205
APA dayi a, dayi o, kurt e, Yorguner N (2020). Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. Türk Psikiyatri Dergisi, 31(4), 239 - 243. 10.5080/u25205
Chicago dayi ali,dayi ozlem,kurt emel,Yorguner Nese Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. Türk Psikiyatri Dergisi 31, no.4 (2020): 239 - 243. 10.5080/u25205
MLA dayi ali,dayi ozlem,kurt emel,Yorguner Nese Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. Türk Psikiyatri Dergisi, vol.31, no.4, 2020, ss.239 - 243. 10.5080/u25205
AMA dayi a,dayi o,kurt e,Yorguner N Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. Türk Psikiyatri Dergisi. 2020; 31(4): 239 - 243. 10.5080/u25205
Vancouver dayi a,dayi o,kurt e,Yorguner N Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları. Türk Psikiyatri Dergisi. 2020; 31(4): 239 - 243. 10.5080/u25205
IEEE dayi a,dayi o,kurt e,Yorguner N "Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları." Türk Psikiyatri Dergisi, 31, ss.239 - 243, 2020. 10.5080/u25205
ISNAD dayi, ali vd. "Kannabis Kullanan Olgularda Optik Koherens Tomografi Bulguları". Türk Psikiyatri Dergisi 31/4 (2020), 239-243. https://doi.org/10.5080/u25205