Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler

MANCAK, METHİYE; koca, ufuk; Durbilmez, Gökşen Dilşat

doi:10.5336/jtracom.2020-76256

Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler

Gökşen Dilşat DURBİLMEZ, (Gazi Üniversitesi, Eczacılık Fakültesi, Farmakognozi Amabilim Dalı, Ankara, Türkiye)

Methiye MANCAK KARAKUŞ, (Gazi Üniversitesi, Eczacılık Fakültesi, Farmakognozi Amabilim Dalı, Ankara, Türkiye)

Ufuk KOCA-ÇALIŞKAN (Gazi Üniversitesi, Eczacılık Fakültesi, Farmakognozi Amabilim Dalı, Ankara, Türkiye)

Geleneksel ve Tamamlayıcı Tıp Dergisi

28 4

Yıl: 2021 Cilt: 4 Sayı: 1 Sayfa Aralığı: 131 - 146 Metin Dili: Türkçe DOI: 10.5336/jtracom.2020-76256 İndeks Tarihi: 28-09-2021

Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler

Öz:

Tiroid bezi, larinksin sonu ve trakeanın başlangıcının 2 tarafındasağda ve solda bulunan, oldukça vasküler yapılı bir bezdir. Tiroidhormonlarını [triyodotironin (T3) ve tiroksin (T4)] üretir, depolar vesalgılar. Tiroid hormonları büyüme, gelişme ve metabolizma için de oldukçaönemlidir. Hipotiroidizm, hipertiroidizm, ötiroid, guatr, tiroidnodülleri, tiroidit ve tiroid kanserleri tiroid bezi fonksiyon bozukluklarındankaynaklanmaktadır. Tiroid hormonu sentezlenmesi ve salgılanmasısırasında meydana gelen herhangi bir problem, bu hastalıklarasebep olabilir. Tiroid hormonlarının sentezi ve salınımındaki anomaliler,hem bazal metabolik oranın değişmesine hem de buna bağlı olarakpek çok sağlık problemine yol açmaktadır. Farklı sebeplerle ortayaçıkan tiroid semptomlarının düzelmesi için insanlar, bitkilerle tedavigibi doğal yöntemlere başvurmaktadırlar. Literatür incelemeleri sonucunda,bitkilerin tiroid fonksiyon bozuklarında etkili ve güvenilir şekildekullanımıyla ilgili az sayıda klinik çalışma tespit edilmiştir. Buderlemede, bu klinik çalışmalar ve daha detaylı olarak bitkilerin etnobotanikve etnofarmakolojik verileri incelenmiştir. Kullanım amacınabağlı olarak, tıbbi bitkilerin tiroid bezi metabolizmasına, tiroid hormonlarınave tiroid bezi fonksiyon bozukluklarının tedavisine olan etkilerineyer verilmiştir. Çalışmamızda, tiroid fonksiyon bozukluklarındafaydalı olduğu düşünülen 42 farklı familyadan, 68 farklı bitki bulunmaktadır.Konuyla ilgili yaklaşık 36 bitki üzerinde in vivo çalışma yapıldığıtespit edilmiştir. Bu bitkilerin, genellikle hipotiroidi veyahipertiroidide etkili olduğu gösterilmiştir. Literatür incelemeleri sonucunda,halk tarafından genellikle bitkilerin yapraklarından hazırlanansulu ekstrelerin kullanıldığı belirlenmiştir. Bu derlemenin, tiroid fonksiyonbozukluklarının bitkisel ilaçlarla tedavisine yönelik ileride yapılacakaraştırmalara ışık tutabileceği düşünülmektedir.

Anahtar Kelime:

Phytotherapeutic Options in Thyroid Function Disorders

Öz:

Thyroid gland is vascular gland located on the right and left sides of the end of the larynx the beginning of the trachea. It produces, stores, secretes thyroid hormones. Thyroid hormones are important for growth, development, metabolism. Thyroid gland dysfunctions: hypothyroidism, hyperthyroidism, euthyroid, goiter, thyroid nodules, thyroiditis, thyroid cancers. Any problems in the synthesis, secretion of thyroid hormone may be the cause of these diseases. Abnormalities in the synthesis, secretion of thyroid hormones lead to both changes in the basal metabolic rate and health problems. People resort to natural methods such as treatment with plants to improve thyroid symptoms that occur for different reasons. As a result of the literature reviews, few clinical studies have been identified regarding the effective and reliable use of plants in thyroid dysfunction. In this review, these clinical studies and ethnobotanical, ethnopharmacological data of these plants were examined in more detail. Depending on the intended use, the effects of medicinal plants on thyroid gland metabolism, thyroid hormones, treatment of thyroid gland dysfunctions are included. In our study, there are 68 different plants from 42 different families that are thought to be beneficial in thyroid dysfunction and 36 in vivo studies. These plants have generally been found to be effective in hypothyroidism or hyperthyroidism. As a result of literature reviews, it is determined that the leaves of plants are used for water extracts. It is thought that this review may shed some light on further research on the treatment of thyroid dysfunction with herbal medicines.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Durbilmez G, MANCAK M, koca u (2021). Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. , 131 - 146. 10.5336/jtracom.2020-76256
Chicago	Durbilmez Gökşen Dilşat,MANCAK METHİYE,koca ufuk Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. (2021): 131 - 146. 10.5336/jtracom.2020-76256
MLA	Durbilmez Gökşen Dilşat,MANCAK METHİYE,koca ufuk Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. , 2021, ss.131 - 146. 10.5336/jtracom.2020-76256
AMA	Durbilmez G,MANCAK M,koca u Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. . 2021; 131 - 146. 10.5336/jtracom.2020-76256
Vancouver	Durbilmez G,MANCAK M,koca u Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. . 2021; 131 - 146. 10.5336/jtracom.2020-76256
IEEE	Durbilmez G,MANCAK M,koca u "Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler." , ss.131 - 146, 2021. 10.5336/jtracom.2020-76256
ISNAD	Durbilmez, Gökşen Dilşat vd. "Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler". (2021), 131-146. https://doi.org/10.5336/jtracom.2020-76256

APA	Durbilmez G, MANCAK M, koca u (2021). Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. Geleneksel ve Tamamlayıcı Tıp Dergisi, 4(1), 131 - 146. 10.5336/jtracom.2020-76256
Chicago	Durbilmez Gökşen Dilşat,MANCAK METHİYE,koca ufuk Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. Geleneksel ve Tamamlayıcı Tıp Dergisi 4, no.1 (2021): 131 - 146. 10.5336/jtracom.2020-76256
MLA	Durbilmez Gökşen Dilşat,MANCAK METHİYE,koca ufuk Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. Geleneksel ve Tamamlayıcı Tıp Dergisi, vol.4, no.1, 2021, ss.131 - 146. 10.5336/jtracom.2020-76256
AMA	Durbilmez G,MANCAK M,koca u Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. Geleneksel ve Tamamlayıcı Tıp Dergisi. 2021; 4(1): 131 - 146. 10.5336/jtracom.2020-76256
Vancouver	Durbilmez G,MANCAK M,koca u Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler. Geleneksel ve Tamamlayıcı Tıp Dergisi. 2021; 4(1): 131 - 146. 10.5336/jtracom.2020-76256
IEEE	Durbilmez G,MANCAK M,koca u "Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler." Geleneksel ve Tamamlayıcı Tıp Dergisi, 4, ss.131 - 146, 2021. 10.5336/jtracom.2020-76256
ISNAD	Durbilmez, Gökşen Dilşat vd. "Tiroid Fonksiyon Bozukluklarında Fitoterapötik Seçenekler". Geleneksel ve Tamamlayıcı Tıp Dergisi 4/1 (2021), 131-146. https://doi.org/10.5336/jtracom.2020-76256