TY  - JOUR
TI  - Familial Mediterranean fever: Health-related quality of life and associated variables in a national cohort
AB  - Objectives: This study aims to evaluate the effectivity of Familial Mediterranean Fever Quality of Life (FMF-QoL) Scale for the measurement of QoL in patients with FMF and to perform correlations between related clinical variables in Turkish patients.Patients and methods: This multicenter prospective study performed between December 2017 and November 2018 included 974 FMF patients (334 males, 640 females; median age: 35; range, 26 to 45 years). Sociodemographic characteristics and clinical features were recorded. All participants were asked to complete the FMF-QoL Scale, Short Form-36 (SF-36), Hospital Anxiety and Depression Scale (HADS), Health Assessment Questionnaire (HAQ), and Functional Assessment of Chronic Illness Therapy (FACIT) Scale.Results: The median FMF-QoL Scale score was 26. Higher FMF-QoL Scale scores were shown to be related to female sex, illiteracy or primary education, monthly low-income (US$<300), smoking, late-onset FMF (>20 years), a higher number of attacks per month (>1/month), and severe disease. FMF-QoL Scale scores were correlated negatively with subscales of SF-36, and positively with HADS-anxiety and HADS-depression scores, HAQ and FACIT.Conclusion: Female sex, smoking, lower educational status, more severe disease, fatigue, and functional impairment were associated with poor QoL. FMF-QoL Scale was noted as a valid and simple patient-reported outcome instrument and correlated with the SF-36 scale.
AU  - gurer, gülcan
AU  - Bodur, Hatice
AU  - Alkan Melikoglu, Meltem
AU  - Keskin, Yaşar
AU  - Çağlayan, Gökhan
AU  - ÇEVİK, REMZİ
AU  - KAPLAN, HÜSEYİN
AU  - ketenci, sertaç
AU  - YURDAKUL, Ozan Volkan
AU  - NAYIMOGLU, MEHMET
AU  - Sarifakioglu, Banu
AU  - Ecesoy, Hilal
AU  - günendi, zafer
AU  - cengiz, ahmet kivanc
AU  - Duruöz, Mehmet Tuncay
AU  - Uçar, Ülkü
AU  - Altıntaş, Duygu
AU  - Sargın, Betül
AU  - Sezer, Ilhan
AU  - ataman, sebnem
AU  - Calis, Mustafa
AU  - DEVECI, HÜLYA
AU  - AYDIN, YILDIRAY
AU  - Çay, Hasan Fatih
AU  - Şen, Nesrin
AU  - NAS, Kemal
AU  - karahan, ali yavuz
AU  - toprak, murat
AU  - demir, ali nail
AU  - hizmetli, sami
AU  - Yurdakul, Fatma
DO  - 10.46497/ArchRheumatol.2021.8215
PY  - 2021
JO  - Archives of Rheumatology
VL  - 36
IS  - 2
SN  - 2148-5046
SP  - 159
EP  - 166
DB  - TRDizin
UR  - http://search/yayin/detay/445721
ER  -