Yıl: 2021 Cilt: 27 Sayı: 2 Sayfa Aralığı: 117 - 120 Metin Dili: İngilizce DOI: 10.4274/tod.galenos.2020.26918 İndeks Tarihi: 01-10-2021

Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature

Öz:
Cystic fibrosis is a common genetic disease of the white population with autosomal recessive inheritance. It may present with sinopulmonary,gastrointestinal, genitourinary, bone and joint findings. Osteoporosis, osteopenia, and fractures are musculoskeletal problems related to thedisease. Although vertebral fractures are common, non-vertebral fractures have been reported rarely. In this case report, we present the caseof a 9-year-old girl with osteopenia-induced femoral neck stress fracture caused by cystic fibrosis. During hospitalization for sinopulmonaryinfection, the patient presented to our clinic with left thigh pain without trauma. The left hip joint was examined and found to be clear.Anterior posterior X-ray examination of the patient, who had difficulty in stepping, revealed no displaced fracture. The patient was laterdiagnosed with type 2 Fullerton & Snowdy fracture, and surgical fixation was ruled out. The patient was successfully treated with non-steroidalanti-inflammatory drugs and immobilization.
Anahtar Kelime:

Pediatrik Femur Boyun Stres Kırığı Olan Kistik Fibroz: Bir Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Öz:
Kistik fibrozis otozomal resesif geçişli, beyaz ırkın sık görülen bir genetik hastalığıdır. Sinopulmoner, gastrointestinal, genitoüriner, kemik ve eklem bulguları ile karşımıza çıkabilir. Osteoporoz, osteopeni ve kırıklar hastalığa bağlı kas-iskelet sistemi sorunlarıdır. Vertebra kırıkları sık görülmekle birlikte nadiren vertebra dışı kırıklar bildirilmiştir. Biz olgu sunumumuzda kistik fibrozisin yol açtığı osteopeniye bağlı femur boyun stres kırığı olan 9 yaşındaki bir kız hastayı sunmaktayız. Sinopulmoner enfeksiyon nedeni ile yatışı esnasında, travmasız sol uyluk ağrısı ve yük vermede zorluk nedeni ile tarafımıza danışılan hastanın anterior posterior radyografik değerlendirmesinde patolojik bulguya rastlanmayıp, manyetik rezonans görüntüleme sonucunda sol femur boynunda deplase olmayan kırık görüntüsü saptandı. Fullerton & Snowdy tip 2 olarak değerlendirilen hastaya cerrahi fiksasyon düşünülmedi. Non-steroid anti-enflamatuvar ilaç ve immobilizasyon ile başarılı şekilde tedavi edildi. Anahtar kelimeler: Kistik fibrozis, stres kırığı, çocuk femur boyun kırığı
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Paccou J, Zeboulon N, Combescure C, Gossec L, Cortet B. The prevalence of osteoporosis, osteopenia, and fractures among adults with cystic fibrosis: a systematic literature review with metaanalysis. Calcif Tissue Int 2010;86:1-7.
  • 2. Haworth CS, Selby PL, Webb AK, Dodd ME, Musson H, McL Niven R, et al. Low bone mineral density in adults with cystic fibrosis. Thorax 1999;54:961-7.
  • 3. Elkin SL, Fairney A, Burnett S, Kemp M, Kyd P, Burgess J, et al. Vertebral deformities and low bone mineral density in adults with cystic fibrosis: a cross-sectional study. Osteoporos Int 2001;12:366- 72.
  • 4. Beaty JH, Kasser JR. Rockwood and Wilkins. Fractures in Children. Philadelphia: Lippincott, William &Wilkins; 2010. p. 769-96.
  • 5. Palocaren T. Femoral Neck Fractures in Children: A Review. Indian J Orthop 2018;52:501-6.
  • 6. Haddad FS, Bann S, Hill RA, Jones DH. Displaced stress fracture of the femoral neck in an active amenorrhoeic adolescent. Br J Sports Med 1997;31:70-2.
  • 7. Scott MP, Finnoff JT, Davis BA. Femoral neck stress fracture presenting as gluteal pain in a marathon runner: case report. Arch Phys Med Rehabil 1999;80:236-8.
  • 8. Warden SJ, Burr DB, Brukner PD. Stress fractures: pathophysiology, epidemiology, and risk factors. Curr Osteoporos Rep 2006;4:103-9.
  • 9. Umans H, Pavlov H. Stress fractures of the lower extremities. Semin Roentgenol 1994;29:176-93.
  • 10. Conway SP, Morton AM, Oldroyd B, Truscott JG, White H, Smith AH, et al. Osteoporosis and osteopenia in adults and adolescents with cystic fibrosis: prevalence and associated factors. Thorax 2000;55:798-804.
  • 11. Bianchi ML, Romano G, Saraifoger S, Costantini D, Limonta C, Colombo C. BMD and body composition in children and young patients affected by cystic fibrosis. J Bone Miner Res 2006;21:388-96.
  • 12. Sermet-Gaudelus I, Souberbielle JC, Ruiz JC, Vrielynck S, Heuillon B, Azhar I, et al. Low bone mineral density in young children with cystic fibrosis. Am J Respir Crit Care Med 2007;175:951-7.
  • 13. Elkin SL, Vedi S, Bord S, Garrahan NJ, Hodson ME, Compston JE. Histomorphometric analysis of bone biopsies from the iliac crest of adults with cystic fibrosis. Am J Respir Crit Care Med 2002;166:1470-4.
  • 14. King SJ, Topliss DJ, Kotsimbos T, Nyulasi IB, Bailey M, Ebeling PR, et al. Reduced bone density in cystic fibrosis: DeltaF508 mutation is an independent risk factor. Eur Respir J 2005;25:54-61.
  • 15. Werntz JR, Lane JM. The biology of pathologic fracture repair. In: Lane JM, Healey JH, (editors). Diagnosis and management of pathologic fractures. New York: Raven; 1993; p. 1-11.
  • 16. Pouilles JM, Bernard J, Tremollières F, Louvet JP, Ribot C. Femoral bone density in young male adults with stress fractures. Bone 1989;10:105-8.
  • 17. Consensus development conference: prophylaxis and treatment of osteoporosis. Am J Med 1991;90:107-10.
  • 18. Fullerton LR Jr, Snowdy HA. Femoral neck stress fractures. Am J Sports Med 1988;16:365-77.
  • 19. Robertson GA, Wood AM. Femoral Neck Stress Fractures in Sport: A Current Concepts Review. Sports Med Int Open 2017;1:E58-E68.
  • 20. Biz C, Berizzi A, Crimì A, Marcato C, Trovarelli G, Ruggieri P. Management and treatment of femoral neck stress fractures in recreational runners: a report of four cases and review of the literature. Acta Biomed 2017;88:96-106.
  • 21. Lim AY, Isopescu S, Thickett KM, Gumery LB, Darby AJ, Honeybourne D, et al. Bilateral fractured neck of the femur in an adult patient with cystic fibrosis. Eur J Intern Med 2003;14:196-8.
  • 22. Haworth CS, Freemont AJ, Webb AK, Dodd ME, Selby PL, Mawer EB, et al. Hip fracture and bone histomorphometry in a young adult with cystic fibrosis. Eur Respir J 1999;14:478-9.
APA Sahbat Y, Akgülle A (2021). Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. , 117 - 120. 10.4274/tod.galenos.2020.26918
Chicago Sahbat Yavuz,Akgülle Ahmet Hamdi Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. (2021): 117 - 120. 10.4274/tod.galenos.2020.26918
MLA Sahbat Yavuz,Akgülle Ahmet Hamdi Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. , 2021, ss.117 - 120. 10.4274/tod.galenos.2020.26918
AMA Sahbat Y,Akgülle A Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. . 2021; 117 - 120. 10.4274/tod.galenos.2020.26918
Vancouver Sahbat Y,Akgülle A Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. . 2021; 117 - 120. 10.4274/tod.galenos.2020.26918
IEEE Sahbat Y,Akgülle A "Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature." , ss.117 - 120, 2021. 10.4274/tod.galenos.2020.26918
ISNAD Sahbat, Yavuz - Akgülle, Ahmet Hamdi. "Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature". (2021), 117-120. https://doi.org/10.4274/tod.galenos.2020.26918
APA Sahbat Y, Akgülle A (2021). Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. Türk Osteoporoz Dergisi, 27(2), 117 - 120. 10.4274/tod.galenos.2020.26918
Chicago Sahbat Yavuz,Akgülle Ahmet Hamdi Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. Türk Osteoporoz Dergisi 27, no.2 (2021): 117 - 120. 10.4274/tod.galenos.2020.26918
MLA Sahbat Yavuz,Akgülle Ahmet Hamdi Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. Türk Osteoporoz Dergisi, vol.27, no.2, 2021, ss.117 - 120. 10.4274/tod.galenos.2020.26918
AMA Sahbat Y,Akgülle A Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. Türk Osteoporoz Dergisi. 2021; 27(2): 117 - 120. 10.4274/tod.galenos.2020.26918
Vancouver Sahbat Y,Akgülle A Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature. Türk Osteoporoz Dergisi. 2021; 27(2): 117 - 120. 10.4274/tod.galenos.2020.26918
IEEE Sahbat Y,Akgülle A "Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature." Türk Osteoporoz Dergisi, 27, ss.117 - 120, 2021. 10.4274/tod.galenos.2020.26918
ISNAD Sahbat, Yavuz - Akgülle, Ahmet Hamdi. "Cystic Fibrosis with Paediatric Femoral Neck Stress Fracture: A Case Report and the Review of Literature". Türk Osteoporoz Dergisi 27/2 (2021), 117-120. https://doi.org/10.4274/tod.galenos.2020.26918