Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea
Yıl: 2021 Cilt: 27 Sayı: 3 Sayfa Aralığı: 271 - 277 Metin Dili: İngilizce DOI: 10.9775/kvfd.2020.24894 İndeks Tarihi: 03-10-2021
Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea
Öz: The aim of this study was to investigate the relationship between serum homocysteine (HCY), and creatinine, urea, venous blood gas andelectrolytes values in neonatal calves with diarrhea. The study was conducted on a total of 30 calves, 20 with diarrhea and 10 healthy (control),with diarrhea complaints, of diff erent races, sexes and ages ranging from 2-24 days. According to the venous blood gas results, the pCO2 andbase deficit values of calves with diarrhea were significantly higher (P<0.001) compared to the control group values, while pH, pO2 and HCO3values were significantly lower (P<0.001). While serum Na+ and Cl- concentrations in diarrheic calves did not show any statistical changewhen compared to the control group (P>0.05), serum K+ concentrations were statistically higher (P<0.001). Serum HCY, folate and vitaminB12 concentration values of diarrheic calves were significantly higher (P<0.001) when compared to the control group. As a result; in neonatalcalves with diarrhea, it has been concluded that homocystein excretion is disrupted by low renal excretion due to decrease in glomerularfiltration rate that caused hyperhomocysteine. In addition, it is thought that this study will shed light on studies that will reveal the eff ect ofhyperhomocysteinemia in the cardiovascular system in diarrheic calves.
Anahtar Kelime: Yenidoğan İshalli Buzağılarda Homosistein Düzeylerinin Değerlendirilmesi
Öz: Bu çalışmanın amacı ishalli yenidoğan buzağılarda serum homosistein (HCY) ile kreatinin, üre, venöz kan gazı ve elektrolit değerleri arasındaki ilişkiyi araştırmaktır. Araştırma, ishal şikayeti olan, farklı ırk ve cinsiyette ve yaşları 2-24 gün arasında değişen 20 ishalli ve 10 sağlıklı (kontrol) olmak üzere toplam 30 buzağı üzerinde yürütüldü. Venöz kan gazı sonuçlarına göre, ishalli buzağıların pCO2 ve baz açığı değerleri kontrol grubu değerlerine göre önemli (P<0.001) düzeyde yüksek belirlenirken, pH, pO2 ve HCO3 değerleri anlamlı (P<0.001) düzeyde düşük saptandı. İshalli buzağılarda Na+ ve Cl-elektrolit konsantrasyonlarının seviyeleri kontrol grubuna göre anlamlı bulunmazken, serum K+ elektrolit konsantrasyon seviyeleri kontrol grubuna göre önemli düzeyde (P<0.001) yüksek tespit edildi. İshalli buzağıların serum HCY, folat ve vitamin B12 konsantrasyon değerleri kontrol grubuna göre anlamlı olarak yüksek (P<0.001) bulundu. Sonuç olarak; yenidoğan ishalli buzağılarda sıvı kaybına bağlı olarak dolaşımdaki sıvı hacmi azalmakta ve böbreklerin glomüler filtrasyon hızı düşmektedir. Böbreklerde düşen glomüler filtrasyon hızına bağlı olarak homosisteinin böbrek yoluyla atılımı aksamakta ve sonucunda da hiperhomosisteine neden olmaktadır. Ayrıca ishal vakalarında artan homosistein konsantrasyonlarının kardiyovasküler sistemde bozukluklara neden olup olmadığına yönelik yapılacak araştırmalara ışık tutacaktır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | kozat S, OZKAN C, okman e (2021). Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. , 271 - 277. 10.9775/kvfd.2020.24894 |
| Chicago | kozat Süleyman,OZKAN CUMALI,okman eda Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. (2021): 271 - 277. 10.9775/kvfd.2020.24894 |
| MLA | kozat Süleyman,OZKAN CUMALI,okman eda Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. , 2021, ss.271 - 277. 10.9775/kvfd.2020.24894 |
| AMA | kozat S,OZKAN C,okman e Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. . 2021; 271 - 277. 10.9775/kvfd.2020.24894 |
| Vancouver | kozat S,OZKAN C,okman e Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. . 2021; 271 - 277. 10.9775/kvfd.2020.24894 |
| IEEE | kozat S,OZKAN C,okman e "Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea." , ss.271 - 277, 2021. 10.9775/kvfd.2020.24894 |
| ISNAD | kozat, Süleyman vd. "Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea". (2021), 271-277. https://doi.org/10.9775/kvfd.2020.24894 |
| APA | kozat S, OZKAN C, okman e (2021). Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 27(3), 271 - 277. 10.9775/kvfd.2020.24894 |
| Chicago | kozat Süleyman,OZKAN CUMALI,okman eda Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 27, no.3 (2021): 271 - 277. 10.9775/kvfd.2020.24894 |
| MLA | kozat Süleyman,OZKAN CUMALI,okman eda Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.27, no.3, 2021, ss.271 - 277. 10.9775/kvfd.2020.24894 |
| AMA | kozat S,OZKAN C,okman e Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2021; 27(3): 271 - 277. 10.9775/kvfd.2020.24894 |
| Vancouver | kozat S,OZKAN C,okman e Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2021; 27(3): 271 - 277. 10.9775/kvfd.2020.24894 |
| IEEE | kozat S,OZKAN C,okman e "Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 27, ss.271 - 277, 2021. 10.9775/kvfd.2020.24894 |
| ISNAD | kozat, Süleyman vd. "Evaluation of Homocysteine Levels in Neonatal Calves with Diarrhea". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 27/3 (2021), 271-277. https://doi.org/10.9775/kvfd.2020.24894 |
