TY  - JOUR
TI  - Outcomes of COVID-19 Patients Hospitalized in a University Hospital, Turkey
AB  - Background: We aimed to assess the risk factors for severe COVID-19 and investigate thedifferences between intensive care unit (ICU) and non-ICU patients.Method: The clinical, radiological, and laboratory characteristics of confirmed COVID-19patients between March 15, 2020, and May 30, 2020, were evaluated retrospectively.Results: A total of 157 patients were included in the study. The median age of the patientswas 47, and 55% were male. Seventeen of them were treated in ICU. All of the patientswho were followed up in ICU were over 50 years old, and 70% were over 65 years old. Themost common comorbid diseases were hypertension (HT) (20%) and diabetes mellitus (DM)(14%). The rates of HT and DM were significantly higher in ICU patients (p <0.001 and p =0.003).The most-reported symptom was cough (58%). Lymphocyte and thrombocyte levels ofICU patients were lower than non-ICU patients, and median AST, ALT, blood urea nitrogen(BUN), creatinine and LDH levels were significantly higher (p <0.001).Hydroxychloroquine was initiated to all patients; however, the treatment duration waslonger in ICU patients (p <0.001). Favipravir treatment was applied in 94% of the ICUpatients, while 15% of the non-ICU patients (p <0.001). A nosocomial infection developed in58% of the patients in the ICU. Twelve (71%) of the ICU patients received invasive mechanicalventilation, and nine died. The intensive care fatality rate was 59%, while the total fatalityrate was 6%.Conclusion: The patients with a confirmed diagnosis of COVID-19 who needed ICU hadolder age and higher comorbidity. Lymphopenia, thrombocytopenia, liver function testdisorder, and high D-dimer, CRP, and troponin levels may be significant for the severity ofthe disease.
AU  - TÜRE, Zeynep Ture
AU  - YILDIZ, ORHAN
AU  - Temel, Şahin
AU  - gökahmetoğlu, selma
AU  - tutar, nuri
AU  - baran ketencioğlu, burcu
AU  - TOK, TUĞBA
AU  - Zararsiz, Gokmen
AU  - Gündoğan, Kürşat
AU  - Kalin Unuvar, Gamze
AU  - Aygen, Bilgehan
DO  - 10.36519/idcm.2020.0020
PY  - 2020
JO  - Infectious diseases and clinical microbiology (Online)
VL  - 2
IS  - 2
SN  - 2667-646X
SP  - 61
EP  - 70
DB  - TRDizin
UR  - http://search/yayin/detay/452059
ER  -