Yıl: 2021 Cilt: 30 Sayı: 3 Sayfa Aralığı: 243 - 246 Metin Dili: İngilizce DOI: 10.5152/turkjnephrol.2021.4755 İndeks Tarihi: 27-10-2021

Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury

Öz:
Sodium phosphate-based enema preparations are low-volume, hyperosmotic agents commonly used in bowel preparation for sigmoidoscopy/colonoscopy and surgical operation. Although generally safe and well tolerated in adults, severemetabolic complications have been reported with use. The patient in this case report was admitted to the general surgerydepartment with complaints of nausea, vomiting, and abdominal pain after oral sodium phosphate solution. After clinicalevaluation, hemodialysis was started for acute kidney injury (AKI). Clinicians should be alert using sodium phosphate solution for bowel cleansing before sigmoidoscopy/colonoscopy and surgical operation, in terms of acute kidney damage andelectrolyte imbalance.
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  • 1. Tooson JD, Gates Jr LK. Bowel preparation before colonoscopy. Choosing the best lavage regimen. Postgrad Med. 1996;100(2):203- 4, 207. [CrossRef]
  • 2. Martin RR, Lisehora GR, Braxton M, Barcia PJ. Fatal poisoning from sodium phosphate enema. Case report and experimental study. JAMA. 1987;257(16):2190-2192. [CrossRef]
  • 3. Oxnard SC, O'Bell J, Grupe WE. Severe tetany in an azotemic child related to a sodium phosphate enema. Pediatrics. 1974;53(1):105-106.
  • 4. Davis RF, Eichner JM, Bleyer WA, Okamoto G. Hypocalcemia, hyperphosphatemia and dehydration following a single hypertonic phosphate enema. J Pediatr. 1977;90(3):484-485. [CrossRef]
  • 5. Reedy JC, Zwiren GT. Enema-induced hypocalcemia and hyperphosphatemia leading to cardiac arrest during induction of anesthesia in an outpatient surgery center. Anesthesiology. 1983;59(6):578-579. [CrossRef].
  • 6. Gonlusen G, Akgun H, Ertan A, Olivero J, Truong LD. Renal failure and nephrocalcinosis associated with oral sodium phosphate bowel cleansing: clinical patterns and renal biopsy findings. Arch Pathol Lab Med. 2006;130(1):101-106. [CrossRef]
  • 7. Hookey LC, Depew WT, Vanner S. The safety profile of oral sodium phosphate for colonic cleansing before colonoscopy in adults. Gastrointest Endosc. 2002;56(6):895-902. [CrossRef]
  • 8. Tan HL, Liew QY, Loo S, Hawkins R. Severe hyperphosphataemia and associated electrolyte and metabolic derangement following the administration of sodium phosphate for bowel preparation. Anaesthesia. 2002;57(5):478-483. [CrossRef]
  • 9. Markowitz GS, Nasr SH, Klein P, et al. Renal failure due to acute nephrocalcinosis following oral sodium phosphate bowel cleansing. Hum Pathol. 2004;35(6):675-684. [CrossRef]
  • 10. Markowitz GS, Whelan J, D’Agati VD. Renal failure following bowel cleansing with a sodium phosphate purgative. Nephrol Dial Transplant. 2005;20(4):850-851. [CrossRef]
  • 11. Gray RW, Wilz DR, Caldas AE, Lemann J Jr. The importance of phosphate in regulating plasma 1,25-(OH)2-vitamin D levels in humans: studies in healthy subjects in calcium-stone formers and in patients with primary hyperparathyroidism. J Clin Endocrinol Metab. 1977;45(2):299-306. [CrossRef]
  • 12. Biberstein M, Parker BA. Enema-induced hyperphosphatemia. Am J Med. 1985;79(5):645-646. [CrossRef]
  • 13. Markowitz GS, Stokes MB, Radhakrishnan J, D’Agati VD. Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an underrecognized cause of chronic renal failure. J Am Soc Nephrol. 2005;16(11):3389-3396. [CrossRef]
  • 14. Pitcher DE, Ford RS, Nelson MT, Dickinson WE. Fatal hypocalcemic, hyperphosphatemic, metabolic acidosis following sequential sodium phosphate-based enema administration. Gastrointest Endosc. 1997;46(3):266-268. [CrossRef]
  • 15. Knobel B, Petchenko P. Hyperphosphatemic hypocalcemic coma caused by hypertonic sodium phosphate(Fleet)enema intoxication. J Clin Gastroenterol. 1996;23(3):217-219. [CrossRef]
  • 16. Fine A, Patterson J. Severe hyperphosphatemia following phosphate administration for bowel preparation in patients with renal failure: two cases and a review of the literature. Am J Kidney Dis. 1997;29(1):103-105. [CrossRef]
  • 17. Fass R, Do S, Hixson LJ. Fatal hyperphosphatemia following Fleet Phospo-Soda in a patient with colonic ileus. Am J Gastroenterol. 1993;88(6):929-932.
  • 18. Vukasin P, Weston LA, Beart RW. Oral Fleet Phospho-Soda laxativeinduced hyperphosphatemia and hypocalcemic tetany in an adult:report of a case. Dis Colon Rectum. 1997;40(4):497-499. [CrossRef]
  • 19. Ori Y, Rozen-Zvi B, Chagnac A, et al. Fatalities and severe metabolic disorders associated with the use of sodium phosphate enemas: a single center's experience. Arch Intern Med. 2012;172(3):263-265. [CrossRef]
APA Koyuncu s, TUTUŞ B, akgun h, KOÇYİĞİT I, SİPAHİOĞLU M, OYMAK O, Tokgoz B (2021). Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. , 243 - 246. 10.5152/turkjnephrol.2021.4755
Chicago Koyuncu sumeyra,TUTUŞ Büşra,akgun hulya,KOÇYİĞİT Ismail,SİPAHİOĞLU Murat,OYMAK Oktay,Tokgoz Bulent Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. (2021): 243 - 246. 10.5152/turkjnephrol.2021.4755
MLA Koyuncu sumeyra,TUTUŞ Büşra,akgun hulya,KOÇYİĞİT Ismail,SİPAHİOĞLU Murat,OYMAK Oktay,Tokgoz Bulent Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. , 2021, ss.243 - 246. 10.5152/turkjnephrol.2021.4755
AMA Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. . 2021; 243 - 246. 10.5152/turkjnephrol.2021.4755
Vancouver Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. . 2021; 243 - 246. 10.5152/turkjnephrol.2021.4755
IEEE Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B "Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury." , ss.243 - 246, 2021. 10.5152/turkjnephrol.2021.4755
ISNAD Koyuncu, sumeyra vd. "Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury". (2021), 243-246. https://doi.org/10.5152/turkjnephrol.2021.4755
APA Koyuncu s, TUTUŞ B, akgun h, KOÇYİĞİT I, SİPAHİOĞLU M, OYMAK O, Tokgoz B (2021). Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. Turkish journal of nephrology (Online), 30(3), 243 - 246. 10.5152/turkjnephrol.2021.4755
Chicago Koyuncu sumeyra,TUTUŞ Büşra,akgun hulya,KOÇYİĞİT Ismail,SİPAHİOĞLU Murat,OYMAK Oktay,Tokgoz Bulent Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. Turkish journal of nephrology (Online) 30, no.3 (2021): 243 - 246. 10.5152/turkjnephrol.2021.4755
MLA Koyuncu sumeyra,TUTUŞ Büşra,akgun hulya,KOÇYİĞİT Ismail,SİPAHİOĞLU Murat,OYMAK Oktay,Tokgoz Bulent Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. Turkish journal of nephrology (Online), vol.30, no.3, 2021, ss.243 - 246. 10.5152/turkjnephrol.2021.4755
AMA Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. Turkish journal of nephrology (Online). 2021; 30(3): 243 - 246. 10.5152/turkjnephrol.2021.4755
Vancouver Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury. Turkish journal of nephrology (Online). 2021; 30(3): 243 - 246. 10.5152/turkjnephrol.2021.4755
IEEE Koyuncu s,TUTUŞ B,akgun h,KOÇYİĞİT I,SİPAHİOĞLU M,OYMAK O,Tokgoz B "Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury." Turkish journal of nephrology (Online), 30, ss.243 - 246, 2021. 10.5152/turkjnephrol.2021.4755
ISNAD Koyuncu, sumeyra vd. "Severe Complication of Iatrogenic Sodium Phosphate Enema Overdose: Acute Kidney Injury". Turkish journal of nephrology (Online) 30/3 (2021), 243-246. https://doi.org/10.5152/turkjnephrol.2021.4755