Introduction: This study aimed to evaluate the frequency and types ofmedication-related problems in older adults receiving home health care servicesthat were identified through clinical pharmacist-led medication review.Materials and Methods: This pilot study was conducted in patients ≥65 yearsof age who were on polypharmacy and receiving home health care services fromMay 15th, 2019 through October 30th, 2019 in Turkey. A multidisciplinary homecare team, including physicians, nurses and clinical pharmacist, performed thehome visits. Scores on the drug burden index, medication regimen complexityindex, and medication appropriateness index, present of potentially inappropriatemedications, and the medication-related problems were assessed.Results: Among 100 older adults (74 females) with a mean age of 78.5±7.9 years,the median number of medications used was 7 (interquartile range: 5-9); the medianscores of the drug burden index, medication regimen complexity, and medicationappropriateness index were 0.5 (interquartile range: 0-0.8), 21 (interquartile range:17-31), and 13 (interquartile range: 6-16.9), respectively. The problems identifiedwere those related to ‘drug selection’ (66%), ‘education and information’ (58%) and‘monitoring’ (33%). The health care team accepted 84.2% of the recommendationsmade by the clinical pharmacists.Conclusions: The results suggested that clinical pharmacist-led cognitiveservices in a home health care services team could reduce medication-relatedproblems in older adults on polypharmacy.