In the history of Modern Turkish Literature, Kemaletin Kamu (1901-1948) and Gultekin Samanoglu (1927-2003) are two prominent figures of Republican period poetry of Modern Turkish Literature. Two poets show similarities regarding their understanding of art, individual sensitivities, the themes they focused on and their worlds of thought. It is seen that Kamu had influence in certain ways on his successor, Sâmanoğlu. Thus, the two poets’ similar life stories, aesthetical sensitivities and choices of themes necessitate a comparative study. In this study, ‘the theme of absence from home’ that two contemporaries, Kemalettin Kamu and Gültekin Samanoglu, reflected in their works was comparatively studied. In the article, firstly the concept and methodology of comparative literature is emphasized, and the importance of the comparison of the artists living in the same culture is mentioned. Then, a brief evaluation was made about the way homesickness was reflected in Turkish poetry. Later on, the poets’ lives, their understanding of arts, their positions in literary history, and their thematic resources were explained by referring to the similarities and differences. The theme of absence from home reflected by either poet was handled individually, and their approach to this theme and the way they reflected it in their poems were tried to be explained. Similarities and differences in the way the poets handled the theme of of absence from home were stated under a separate heading. It is also understood that Kamu influenced Samanoğlu in transferring the sentiments of homesickness, and the similarities and identicalness of the two poets’ sensitiveness and way of saying as to the theme of sickness are striking. It is also possible to say that poets have certain differences in their handling of the theme of absence from home because of their life experiences.