TY  - JOUR
TI  - Evaluation of kidney function in children with Hashimoto’sThyroiditis
AB  - Aim: Thyroid hormones have various effects on kidney function and both hypothyroidism and hyperthyroidism may result in clinically important alterations in kidney function. Therefore, we evaluated kidney functions and changes in kidney functions over time in children with Hashimoto thyroiditis (HT) who treated or not treated with thyroid hormone replacement therapy. Materials and Methods: The patients were divided into three groups. Group 1 included patients who had hypotroidism and received treatment, group 2 included patients who had euthyroid goiter and received treatment and group 3 consisted of patients who were clinically euthyroid and not received any treatment. All participants were followed prospectively. Serum creatinine (Cr), albumin and serum cystatin C (CysC) levels, estimated glomerular filtration rate eGFR, and urine protein to creatinine ratio (PCR) were measured at the time of diagnosis and one and six months after diagnosis Results: There were significant differences between baseline and follow-up characteristics of the group 1 in terms of serum Cr, urine PCR, CysC and eGFR. The baseline and follow-up characteristics of groups 2 and 3 were not statistically significant. Conclusion: Children with HT may present with kidney dysfunction and proteinuria, which improve with thyroid hormone replacement. We think that clinicians who follow children with HT should pay attention to this issue.
AU  - Hatipoglu, Nihal
AU  - Dursun, Ismail
AU  - OKDEMIR, DENIZ
AU  - Gündüz, Zübeyde
AU  - Yel, Sibel
AU  - Dusunsel, Ruhan
AU  - Yılmaz, Kenan
AU  - baş, veysel
DO  - 10.5455/annalsmedres.2020.05.467
PY  - 2021
JO  - Annals of Medical Research
VL  - 28
IS  - 7
SN  - 2636-7688
SP  - 1302
EP  - 1307
DB  - TRDizin
UR  - http://search/yayin/detay/458389
ER  -