TY  - JOUR
TI  - Diagnostic value of ultrasonograpy and 99mTc-MIBIscintigraphy for preoperative localization of parathyroidadenomas
AB  - Aim: The primary treatment of primary hyperparathyroidism (PHPT) is parathyroidectomy. With its shorter operative time and healing period, lesser general anesthesia duration, lesser hypoparathyroidism risk and better cosmetic results minimally invasive parathyroidectomy is the most commonly performed contemporary surgical procedure. However, in order for this procedure to be successful, it is important to know the location of the parathyroid adenoma. The purpose of this study was to determine the diagnostic value of Ultrasonography (USG) and technetium methoxyisobutylisonitrile scintigraphy (99mTc-MIBI) in the preoperative localization of parathyroid adenoma.Materials and Methods: Fifty-two patients diagnosed with parathyroid adenoma were included in the study. Preoperative parathyroid USG and 99mTc-MIBI were performed on all patients. All patients’ preoperative serum calcium, phosphorus, parathormone and Vitamin D levels, parathyroid USG and 99mTc-MIBI, intraoperative parathyroid lesion location and histopathological examination results were recorded. Results: Patients aged between 22 and 81 (51.7±15.6) were eventually enrolled. When USG was used alone, the site of the adenoma was correctly determined in 26 of the 52 patients with a sensitivity of 52% and a positive predictive value of 92.8%. When scintigraphy was performed alone, the site of the adenoma was correctly identified in 39 of the 52 patients. Sensitivity was thus 76.4% and positive predictive value 97.5%. When USG and scintigraphy were assessed together, adenoma location was correctly identified in 45 of the 52 patients. Sensitivity for the two tests employed together was 88.2% and positive predictive value was 97.8%. Conclusions: Due to the high sensitivity of combined use of USG and 99mTc-MIBI, we recommend the two tests to be assessed together before parathyroid surgery.
AU  - BİLEN, Habib
AU  - BİLEN, Arzu
AU  - Kılıç, Korhan
AU  - Aktan, Bulent
AU  - Sakat, Muhammed Sedat
AU  - Şengöz, Furkan
AU  - Şahin, Abdulkadir
DO  - 10.5455/annalsmedres.2020.06.635
PY  - 2021
JO  - Annals of Medical Research
VL  - 28
IS  - 7
SN  - 2636-7688
SP  - 1351
EP  - 1354
DB  - TRDizin
UR  - http://search/yayin/detay/458432
ER  -