COVID-19 and Phytotherapy

Akcakaya, Adem; AKBAŞ, Melike Nur

doi:10.14235/bas.galenos.2020.4962

COVID-19 and Phytotherapy

Adem AKÇAKAYA, (Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, İstanbul, Türkiye)

Melike Nur AKBAŞ (Bezmialem Vakıf Üniversitesi, Bitki Eczanesi, İstanbul, Türkiye)

Bezmiâlem Science

5 1

Yıl: 2020 Cilt: 8 Sayı: 4 Sayfa Aralığı: 428 - 437 Metin Dili: İngilizce DOI: 10.14235/bas.galenos.2020.4962 İndeks Tarihi: 09-11-2021

COVID-19 and Phytotherapy

Öz:

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus2), emerging in Wuhan city, China, causing COVID-19 disease,has been described as a pandemic by WHO (World HealthOrganization), leading to outbreaks of pneumonia. The COVID-19pandemic continues to affect millions of people worldwide. SARSCOV-2 enters the cell via ACE-2 (Angiotensin-converting enzyme2) receptor. These receptors are predominantly found in lung, smallintestine, and vascular endothelial cells. Since ACE 2 is found morefrequently in these tissues, common clinical symptoms includefever, cough, sore throat, fatigue, dyspnea, and diarrhea. Currently,although symptomatic treatments are applied for COVID-19, thereis no specific treatment yet. It takes a long time before targetedtherapies can be found. For this reason, it is necessary to developemergency treatment or methods that can quickly control thedisease. Phytotherapeutic compositions offer a potentially valuableresource for this purpose. Many countries, especially China,aimed to reduce morbidity and mortality by using phytotherapythroughout COVID-19 patients. Phytotherapeutic products areknown to be safe and tolerable with their background knowledge.In this regard, the use of phytotherapy as a complementarytreatment in COVID-19 patients is very important. In this review,phytotherapeutic approaches related to symptoms that may occur inthe clinical course of COVID-19 disease will be discussed.

Anahtar Kelime:

COVID-19 ve Fitoterapi

Öz:

Çin’in Wuhan şehrinde ortaya çıkan ve COVID-19 hastalığına sebep olan SARS-CoV-2 (Şiddetli Akut Solunum Sendromu Korona Virüsü 2), pnömoni salgınlarına yol açarak DSÖ (Dünya Sağlık Örgütü) tarafından pandemi olarak nitelendirilmiştir. COVID-19 pandemisi dünya genelinde milyonlarca kişiyi etkilemeye devam etmektedir. SARS-COV-2, ACE-2 (Anjiyotensin dönüştürücü enzim 2) reseptörünü kullanarak hücre içine giriş yapmaktadır. Bu reseptörler ağırlıklı olarak akciğer, ince barsak ve vasküler endotel hücrelerinde bulunmaktadır. ACE 2’nin bu dokularda daha sık bulunması sebebiyle, yaygın görülen klinik semptomlar arasında ateş, öksürük, boğaz ağrısı, yorgunluk, dispne ve ishal yer almaktadır. Şu anda, COVID-19 için semptomatik tedaviler uygulansa da henüz spesifik bir tedavisi bulunmamaktadır. Hedefe yönelik tedavilerin bulunabilmesi için çok uzun bir zaman geçmesi gerekmektedir. Bu sebeple acil tedavi veya hızlı bir şekilde hastalığı kontrol altına alabilecek yöntemler geliştirilmesi gerekmektedir. Fitoterapötik bileşimler, bu amaçla potansiyel olarak değerli bir kaynak sunmaktadır. Başta Çin olmak üzere pek çok ülke COVID-19 hastalarında, tedavi seyri boyunca fitoterapiyi uygulayarak morbiditeyi ve mortaliteyi azaltabilmeyi amaçlamıştır. Fitoterapötik ürünler geçmişten gelen bilgi birikimi ile birlikte güvenli ve tolere edilebilir olduğu bilinmektedir. COVID-19 hastalığında tamamlayıcı tedavi olarak kullanımı bu açıdan çok önemlidir. Bu derlemede COVID-19 hastalığının klinik seyrinde ortaya çıkabilecek semptomlara ilişkin fitoterapötik yaklaşımlardan bahsedilecektir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Diğer Erişim Türü: Erişime Açık

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APA	Akcakaya A, AKBAŞ M (2020). COVID-19 and Phytotherapy. , 428 - 437. 10.14235/bas.galenos.2020.4962
Chicago	Akcakaya Adem,AKBAŞ Melike Nur COVID-19 and Phytotherapy. (2020): 428 - 437. 10.14235/bas.galenos.2020.4962
MLA	Akcakaya Adem,AKBAŞ Melike Nur COVID-19 and Phytotherapy. , 2020, ss.428 - 437. 10.14235/bas.galenos.2020.4962
AMA	Akcakaya A,AKBAŞ M COVID-19 and Phytotherapy. . 2020; 428 - 437. 10.14235/bas.galenos.2020.4962
Vancouver	Akcakaya A,AKBAŞ M COVID-19 and Phytotherapy. . 2020; 428 - 437. 10.14235/bas.galenos.2020.4962
IEEE	Akcakaya A,AKBAŞ M "COVID-19 and Phytotherapy." , ss.428 - 437, 2020. 10.14235/bas.galenos.2020.4962
ISNAD	Akcakaya, Adem - AKBAŞ, Melike Nur. "COVID-19 and Phytotherapy". (2020), 428-437. https://doi.org/10.14235/bas.galenos.2020.4962

APA	Akcakaya A, AKBAŞ M (2020). COVID-19 and Phytotherapy. Bezmiâlem Science, 8(4), 428 - 437. 10.14235/bas.galenos.2020.4962
Chicago	Akcakaya Adem,AKBAŞ Melike Nur COVID-19 and Phytotherapy. Bezmiâlem Science 8, no.4 (2020): 428 - 437. 10.14235/bas.galenos.2020.4962
MLA	Akcakaya Adem,AKBAŞ Melike Nur COVID-19 and Phytotherapy. Bezmiâlem Science, vol.8, no.4, 2020, ss.428 - 437. 10.14235/bas.galenos.2020.4962
AMA	Akcakaya A,AKBAŞ M COVID-19 and Phytotherapy. Bezmiâlem Science. 2020; 8(4): 428 - 437. 10.14235/bas.galenos.2020.4962
Vancouver	Akcakaya A,AKBAŞ M COVID-19 and Phytotherapy. Bezmiâlem Science. 2020; 8(4): 428 - 437. 10.14235/bas.galenos.2020.4962
IEEE	Akcakaya A,AKBAŞ M "COVID-19 and Phytotherapy." Bezmiâlem Science, 8, ss.428 - 437, 2020. 10.14235/bas.galenos.2020.4962
ISNAD	Akcakaya, Adem - AKBAŞ, Melike Nur. "COVID-19 and Phytotherapy". Bezmiâlem Science 8/4 (2020), 428-437. https://doi.org/10.14235/bas.galenos.2020.4962