TY  - JOUR
TI  - Clinical Characteristics of 46,XX Males with Congenital Adrenal Hyperplasia
AB  - Objective: To retrospectively evaluate the follow-up data in patients with 46,XX congenital adrenal hyperplasia (CAH) who were raisedmale.Methods: A national database was created. The data of patients were asked to be recorded in the data form.Results: The median (range) age of diagnosis was three (0.1-18.3) years in 44 patients. Twenty nine cases were diagnosed after the ageof two years. Most (95.4%) cases were stage 4-5 virilized. Hysterectomy and bilateral salpingoopherectomy, at a median age of 7.25(2.4-25.3) years, was performed in 35 cases. Testicular prostheses were placed in 11 (25%) cases at a median age of 11.2 (2.8-17) years.The median final height was 149.2 (132.8-172) cms in 38 patients, including simple virilizing (n=18), salt-wasting (n=6), and 11-betahydroxylase (n=12). Of the 16 patients above the age of eighteen, university education was completed in 25%.Conclusion: It was seen that most (65.9%) of the 46,XX CAH cases raised male were diagnosed after two years of age. In these cases,hysterectomy and bilateral salpingoopherectomy, genital corrective surgeries and testicular prosthesis operations were performed in avery wide age rage.
AU  - berberoglu, merih
AU  - aycan, zehra
AU  - gürbüz, fatih
AU  - Öztürk, Ayşe Pınar
AU  - Poyrazoglu, Sukran
AU  - demiral, meliha
AU  - Ozbek, Mehmet Nuri
AU  - Çetinkaya, Semra
AU  - SAVAS ERDEVE, SENAY
AU  - Özsu, Elif
AU  - siklar, zeynep
AU  - unal, edip
AU  - Bas, Firdevs
AU  - akyurek, nesibe
AU  - Darendeliler, Feyza
AU  - Evliyaoğlu, Olcay
AU  - yuksel, bilgin
DO  - 10.4274/jcrpe.galenos.2020.2020.0216
PY  - 2021
JO  - Journal of Clinical Research in Pediatric Endocrinology
VL  - 13
IS  - 2
SN  - 1308-5727
SP  - 180
EP  - 186
DB  - TRDizin
UR  - http://search/yayin/detay/460324
ER  -